Antioxidant and antiaging activities of the polysaccharide ZJP-04M from Ziziphus jujuba in Caenorhabditis elegans.

Aging is a social problem that people pay particular attention to. Oxidative stress is closely related to aging. Natural polysaccharides have numerous biological activities, and they show good application prospect in preventing oxidative stress and aging prospects.

Challenges and strategies toward oncolytic virotherapy for leptomeningeal metastasis.

Meningeal metastasis (LM) is commonly seen in the advanced stages of cancer patients, often leading to a rapid decline in survival time and quality of life. Currently, there is still a lack of standardized treatments. Oncolytic viruses (OVs) are a class of emerging cancer therapeutics with the advantages of selectively replicating in cancer cells, delivering various eukaryotic transgenes, inducing immunogenic cell death, and promoting anti-tumor immunity.

Risk of COVID-19 infection in patients with NSCLC receiving EGFR-TKI targeted therapy during the first wave in China.

Objective: We examined the factors influencing hospitalization and prognosis among patients with non-small cell lung cancer receiving epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) targeted therapy during the first wave of the coronavirus disease 2019 (COVID-19) pandemic.

Methods: In total, 267 patients diagnosed with NSCLC who were receiving treatment with third-generation EGFR-TKIs were included in our retrospective study. Data on patients' demographics, clinical characteristics, and survival were collected and analyzed.

The Effects of Abnormal Exposure on Individual Dose Monitoring with TLD Dosimeters.

Objectives: To analyze the effects of normal x-ray inspection, machine washing, and machine drying on thermoluminescent dosimeter (TLD) measurements during external individual monitoring and to provide suggestions for determining individual monitoring measurements under the mentioned abnormal situations. In this study, we focused on three abnormal situations: x-ray inspection, machine washing, and machine drying, which are common in external individual dose monitoring. We measured and compared the doses from TLD with and without 11, 23, 35, and 50 security checks.

Fast prediction of patient-specific organ doses in brain CT scans using support vector regression algorithm.

. This study aims to develop a method for predicting patient-specific head organ doses by training a support vector regression (SVR) model based on radiomics features and graphics processing unit (GPU)-calculated reference doses..

Does home and community-based services use reduce hospital utilization and hospital expenditure among disabled elders? Evidence from China.

Introduction: In the background of aging in place, home and community-based services (HCBS) have been playing an increasingly important role in long-term care (LTC) security systems. However, it is still uncertain whether and how HCBS use affects hospital utilization and the corresponding expenditures.

Methods: Using data from the China Health and Retirement Longitudinal Survey (CHARLS) and the China City Statistical Yearbook, the instrumental variable (IV) approach is applied to identify the causal effects of HCBS use on hospital utilization and hospital expenditure among disabled elders.

Health effects of long-term care insurance on spouses of disabled people: a quasi-experimental study.

Background: It is still uncertain whether and how formal long-term care (LTC) systems affect the health status of family members. This paper examines the health effects of long-term care insurance (LTCI) on spouses of disabled people in China.

Methods: The data is from China Health and Retirement Longitudinal Survey (CHARLS), a longitudinal survey of a nationally representative sample of Chinese residents aged 45 or older and their spouses, and China City Statistical Yearbook.

Elucidation of the Reinforcing Spleen Effect of Jujube Fruits Based on Metabolomics and Intestinal Flora Analysis.

Jujube ( Mill.) fruit (JF) is widely consumed as food in Asian countries due to its potential effects for human health. As a traditional Chinese medicine, JF is often used to treat anorexia, fatigue and loose stools caused by spleen deficiency syndromes in China, but the mechanism underlying this effect has not been thoroughly elucidated.

Isolation, structural characterization and bioactivities of polysaccharides from Laminaria japonica: A review.

Laminaria japonica is a familiar marine plant and is often used as food due to its abundant carbohydrates, vitamins and minerals. As one of the main types of active substances in L. japonica, polysaccharides are widely used in the food and chemical industries and in medicine and healthcare due to their health benefits, such as immunoregulatory, antioxidant, and antidiabetic effects.

Synthesis of starch nanoparticles with controlled morphology and various adsorption rate for urea.

Starch nanoparticles (SNPs) with different morphology and particle size can be prepared by modulating the reaction conditions over SNPs preparation. This study was to synthesize various SNPs by using ultrasound assisted nanoprecipitation method, and characterized by particle size analysis, SEM and XRD performing. SNPs were successfully produced via nanoprecipitation and the particle size were controlled in the range of 95 to 150 nm.

Trends in radiation exposure from clinical nuclear medicine procedures in Shanghai, China.

Objectives: This study was designed to assess the trends in the frequencies of nuclear medicine procedures in Shanghai, China, and to determine their contributions to the per capita effective dose to the Shanghai population. The mean activities of radionuclides administered by nuclear medicine departments were compared with the Chinese national guidelines on diagnostic reference levels.

Methods: On the basis of the three surveys carried out by Shanghai Municipal Center for Disease Control and Prevention in 1996, 1998, and 2008, the typically administered radiopharmaceuticals, levels of activity, the number of procedures, and population were systematically analyzed to assess the frequencies of nuclear medicine procedures and the per capita effective dose.

Patient doses in different projections of conventional diagnostic X-ray examinations.

The entrance surface doses (ESDs) of six commonly performed diagnostic X-ray projections were surveyed in four public hospitals, and an experimental formula was derived for estimating the ESD from the exposure parameters of different projections. In-phantom measurements of the organ doses were also performed for the six projections, and the effective doses were evaluated using different sets of tissue weighting factors recommended by the International Commission on Radiological Protection (ICRP). For the chest radiograph, compared with the low tube potential technique, lower ESD was observed in the high tube potential technique; however, no significant difference of effective doses was found between the two techniques.

Cross-section measurements for (n, 2n) and (n, alpha) reactions on yttrium at neutron energies from 13.5 to 14.6 MeV.

The cross sections for the reactions (89)Y(n, 2n) (88m+g)Y and (89)Y(n, alpha) (86m+g)RB induced by 14MeV neutrons have been measured using the activation technique and a coaxial HPGe gamma-ray detector. Spectroscopically pure Y(2)O(3) powder was used. Fast neutrons were produced by the T(d, n) (4)He reaction.

Cross-section measurements for the reactions of 14 MeV neutrons on indium isotopes.

The cross sections for the reactions (115)In(n, p)(115g)Cd, (115)In(n, alpha)(112)Ag, (115)In(n, 2n)(114m)In, (113)In(n, 2n)(112m)In, (115)In(n, n')(115m)In, and (113)In(n, n')(113m)In induced by 14 MeV neutrons have been measured by activation relative to the (27)Al(n, alpha)(24)Na. Measurements were carried out by gamma-detection using a coaxial HPGe detector. As samples, natural indium has been used.

Cross-section measurements for the 128Te(n,2n) 127mTe reaction induced by neutrons around 14 MeV.

The cross sections of 128Te(n,2n) 127mTe reaction induced by neutrons around 14 MeV were measured using activation technique and calculated by a previously developed formula. 737+/-69 and 853+/-82 mb at the neutron energies of 14.1+/-0.