[Analysis of prenatal phenotype and pathogenetic variant in a fetus with Papillorenal syndrome].

Objective: To determine the carrier rate of deafness-related genetic variants among 53 873 newborns from Zhengzhou.

Methods: Heel blood samples of the newborns were collected with informed consent from the parents, and 15 loci of 4 genes related to congenital deafness were detected by microarray.

Results: In total 2770 newborns were found to carry deafness-related variants, with a carrier rate of 5.