In this study, 14 abietene and pimarene diterpenoids were isolated from the woods of Agathis dammara. Among them, 4 new compounds, dammarone A-C and dammaric acid A (1-4), were firstly reported, respectively. The structure of the new compounds was determined by HR ESI-MS and 1D/2D NMR spectroscopy, and their absolute configuration was determined by electronic circular dichroism (ECD) exciton chirality method.
View Article and Find Full Text PDFIn this study, two new kaurane diterpenes (16, 17), together with 12 lignans (1-12), a triterpene (15), and two other compounds (13, 14) were isolated from the woods of Agathis dammara. The structure of the new compound was determined by HR ESIMS and 1D/2D NMR spectroscopy, and its absolute configuration was determined by electronic circular dichroism (ECD) exciton chirality method. Compounds 5, 11, 14 exhibit significant hypoglycaemic activity in zebrafish, and their mechanism of action is to enhance glucose uptake in zebrafish.
View Article and Find Full Text PDFIn this study, three new compounds, roxburic acid A () and two flavone glycosides isorhamnetin-3--rhamnosyl-(1→6)--glucopyranose-(1→3)--glucopyranoside (), and kaempferol-7--glucopyranosyl-(1→3)--glucopyranoside () were isolated from an ethanol extract of the fresh (Wall.) Lindl., together with 10 known compounds ().
View Article and Find Full Text PDFJuniperus formosana Hayata (J. formosana) is a commom needlebush cultivar growing in China. Six new compounds (1-6), including four cadinene sesquiterpenoids (1-4), one abietane diterpenoid (5), and one β-naphthol derivative (6), along with 18 known compounds (7-24) were isolated and identified through phytochemical investigation on the heartwood of J.
View Article and Find Full Text PDF