Publications by authors named "Yanli Qian"
Genome-wide DNA methylation profiling of gastric cardia cancer.
J Gastroenterol Hepatol
February 2023
Background And Aim: Aberrant DNA methylation has been found in various cancer types including gastric cancer, yet the genome-wide DNA methylation profile of gastric cardia cancer (GCC) remains unclear. Therefore, we aimed to profile the DNA methylation pattern of GCC and identify promising diagnostic epigenetic biomarkers.
Methods: We investigated the genome-wide DNA methylation pattern in eight pairs of GCC and adjacent normal tissues using Illumina 850K microarrays.
Article Synopsis
- Salinity causes oxidative damage in plants, and flavonoids serve as antioxidants that help manage reactive oxygen species (ROS) in these conditions.
- The study focuses on the tobacco protein NtMYB4, which is suppressed by high salinity and when overexpressed, leads to decreased salt tolerance in transgenic plants.
- The findings suggest that NtMYB4 negatively regulates flavonoid accumulation, notably rutin, leading to reduced ROS-scavenging ability and increased oxidative stress under salinity conditions.