Thickness-dependent surface reconstructions in non-van der Waals two-dimensional materials.

Bismuth oxychalcogenides (BiOX, X = S, Se, Te), a family of non-van der Waals (non-vdW) two-dimensional (2D) semiconductors, are attracting significant attention due to their outstanding semiconducting properties and huge potential in various applications of electronic and optoelectronic devices. Surface imperfections (, surface vacancies) and surface reconstructions are more likely to appear and may cause intriguing physical properties and novel phenomena in the non-vdW 2D materials than the vdW cases. Here, we explore the impacts of surface vacancies and surface reconstructions on the properties of the surfaces and 2D structures of BiOX by using the first-principles method.

First-principles study of the surface energies and electronic structures of γ-CsSnI surfaces.

All-inorganic perovskite CsSnI has attracted intense research interests due to its prominent optoelectronic properties, high thermal stability, and environmentally friendly character. The surface energies and electronic structures of black orthorhombic (γ) CsSnI surfaces are investigated by using first-principles methods. The anisotropic and termination-dependent surface energies of low-index surfaces (, the (110), (001), (100) and (101) surfaces) are obtained, providing important data for CsSnI, since these values are difficult to be measured in experiments.

Semantic-Electromagnetic Inversion With Pretrained Multimodal Generative Model.

Across diverse domains of science and technology, electromagnetic (EM) inversion problems benefit from the ability to account for multimodal prior information to regularize their inherent ill-posedness. Indeed, besides priors that are formulated mathematically or learned from quantitative data, valuable prior information may be available in the form of text or images. Besides handling semantic multimodality, it is furthermore important to minimize the cost of adapting to a new physical measurement operator and to limit the requirements for costly labeled data.

Semantic regularization of electromagnetic inverse problems.

Solving ill-posed inverse problems typically requires regularization based on prior knowledge. To date, only prior knowledge that is formulated mathematically (e.g.

Surface energy and surface stability of cesium tin halide perovskites: a theoretical investigation.

Lead halide perovskites have been widely studied in the fields of photovoltaics and optoelectronics for over a decade. The toxicity of lead poses a big challenge to the potential applications of the materials. In recent years, lead-free halide perovskites have received significant attention due to their excellent optoelectronic properties and environment-friendly character.

Diagnosis of keratoconus in a young male by electrophysiological test findings: A case report.

Rationale: The purpose of this report was to describe the diagnostic process of a case of keratoconus (KCN) after electrophysiological examination.

Patient Concerns: A 23-year-old male army officer presented with decreased visual acuity (VA) in the left eye for 5 months. Best-corrected VA was 20/20 in the right eye and 20/300 in the left eye.

The electrophysiological features of X-linked juvenile retinoschisis in a young male: a case report.

This case report describes the detailed electrophysiological features and the corresponding relationship with the structural changes in a case of X-linked juvenile retinoschisis (XLRS). A 25-year-old male presented with a history of several years of decreased visual acuity in both eyes. The best corrected visual acuity was 20/200 in oculus dexter (OD) and 20/80 in oculus sinister.

Acute lymphocytic leukemia with initial manifestation of serous retinal detachment and choroidal thickening: case report and literature review.

This report describes a patient who had acute lymphocytic leukemia with exudative retinal detachment (RD), which mimicked Vogt-Koyanagi-Harada disease (VKH). A 61-year-old woman presented with painless loss of vision in the left eye. Fundus examination revealed RD in her left eye.

A systematic review of opioid overdose interventions delivered within emergency departments.

Background: People with opioid use disorders are at higher risk of fatal opioid overdose and attend emergency departments (ED) more frequently compared to the general population. This review aimed to synthesise evidence on the ED-based delivery of opioid overdose prevention interventions.

Methods: Using the PRISMA guidelines, four databases (Medline; Embase; Scopus; PsycINFO) were searched for peer-reviewed articles on ED based interventions to prevent opioid overdose, published January 1998 to October 2018.

Guidelines for parenteral and enteral nutrition in geriatric patients in China.

Based on the expert consensus on parenteral and enteral nutrition support for geriatric patients in China in 2013, domestic multidisciplinary experts were gathered to summarize the new evidence in the field of elderly nutritional support at home and abroad. The 2013 consensus was comprehensively updated and upgraded to a guideline by referring to the World Health Organization (WHO) guidelines for the Grading of Recommendations Assessment, Development, and Evaluation system for grading evidence. These guidelines were divided into two parts: general conditions and common diseases.

Cascading detection model for prediction of apnea-hypopnea events based on nasal flow and arterial blood oxygen saturation.

Purpose: Sleep apnea and hypopnea syndrome (SAHS) seriously affects sleep quality. In recent years, much research has focused on the detection of SAHS using various physiological signals and algorithms. The purpose of this study is to find an efficient model for detection of apnea-hypopnea events based on nasal flow and SpO signals.

Fluvastatin Prevents Lung Adenocarcinoma Bone Metastasis by Triggering Autophagy.

Bone is one of the most preferred sites of metastasis in lung cancer. Currently, bisphosphonates and denosumab are major agents for controlling tumor-associated skeletal-related events (SREs). However, both bisphosphonates and denosumab significantly increase the risk for jaw osteonecrosis.

Cell apoptosis, autophagy and necroptosis in osteosarcoma treatment.

Osteosarcoma is the most common primary bone tumor in children and adolescents. Although combined therapy including surgery and multi-agent chemotherapy have resulted in great improvements in the overall survival of patients, chemoresistance remains an obstacle for the treatment of osteosarcoma. Molecular targets or effective agents that are actively involved in cell death including apoptosis, autophagy and necroptosis have been studied.

Status and prospects of percutaneous vertebroplasty combined with ¹²⁵I seed implantation for the treatment of spinal metastases.

Metastatic spinal tumours are the most common type of bone metastasis. Various methods have been used to treat metastatic spinal lesions, including radiotherapy, chemotherapy, isotope therapy, bisphosphonate therapy, analgesics, and surgery. Conservative treatments such as radiotherapy and chemotherapy are not appropriate and usually are ineffective in patients with vertebral fractures and/or spinal instability.

Minimal access versus open spinal surgery in treating painful spine metastasis: a systematic review.

Study Design: The study design of this paper is a systematic review of literature published in the recent 10 years.

Objective: It is the objective of this paper to compare the clinical efficacy and safety of minimal access (MIS) spinal surgery and open spinal surgery for treating painful spine metastasis.

Methods: Two research questions below were determined through a consensus among a panel of spine experts.

Safety of percutaneous vertebroplasty for the treatment of metastatic spinal tumors in patients with posterior wall defects.

Purpose: To assess the clinical effect of percutaneous vertebroplasty (PVP) in the treatment of metastatic spinal tumors in patients with posterior wall defect.

Methods: The treated vertebrae bodies were divided into four groups: group A, non-posterior vertebral wall defect; group B, posterior vertebral wall with cribriform defects; group C, posterior vertebral wall with local fragmentation defects; group D, posterior vertebral wall with severe defects. The injected volume of bone cement, visual analogue scale (VAS) score, Karnofsky Performance Scale (KPS), cement leakage and survival were analyzed.

[Effect of Panax notoginseng saponins on liver drug metablic enzyme activity, mRNA and protein expressions in rats].

To study the effect of Panax notoginseng saponins (PNS) on liver drug metabolic enzyme activity, mRNA and protein expressions in rats. Male Wistar rats were randomly divided into nine groups. After administration of the test drugs, their liver microsomes, liver total RNA and total protein were extracted to detect the regulating effect of PNS on liver drug metabolic enzyme activity-related subtype enzymatic activity, mRNA and protein expression by substrate probe, quantitative PCR and Western Blot technology.

Increased levels of β-catenin, LEF-1, and HPA-1 correlate with poor prognosis for acral melanoma with negative BRAF and NRAS mutation in BRAF exons 11 and 15 and NRAS exons 1 and 2.

To determine the expression of β-catenin, lymphoid enhancer-binding protein-1 (LEF-1), and heparanase-1 (HPA-1) and to evaluate these proteins' potential prognostic values in malignant acral melanoma without mutations in BRAF exons 11 and 15 and NRAS exons 1 and 2, specimens from 90 patients with wild-type BRAF and NRAS were assessed and analyzed by immunohistochemistry and western blotting. The positive expression of β-catenin, lymphoid enhancer-binding protein-1, and heparanase-1 was observed in 36 (72%), 31 (62%), and 32 (64%) of the detected acral melanomas, respectively. The expression of β-catenin, lymphoid enhancer-binding protein-1, and heparanase-1 was not correlated with gender, age, or diseased body parts (p>0.

Meta-analysis of differentially expressed genes in osteosarcoma based on gene expression data.

Background: To uncover the genes involved in the development of osteosarcoma (OS), we performed a meta-analysis of OS microarray data to identify differentially expressed genes (DEGs) and biological functions associated with gene expression changes between OS and normal control (NC) tissues.

Methods: We used publicly available GEO datasets of OS to perform a meta-analysis. We performed Gene Ontology (GO) enrichment analysis, Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis and Protein-Protein interaction (PPI) networks analysis.

Regulation of autophagy via PERK-eIF2α effectively relieve the radiation myelitis induced by iodine-125.

Radiation myelitis is the most serious complication in clinical radiotherapy for spinal metastases. We previously showed that (125)I brachytherapy induced apoptosis of spinal cord neurons accompanied by autophagy. In this study, we further investigated the mechanism by which (125)I radiation triggered autophagy in neural cells.

Genome-wide identification of bone metastasis-related microRNAs in lung adenocarcinoma by high-throughput sequencing.

Background: MicroRNAs (miRNAs) are a class of small noncoding RNAs that regulate gene expression at the post-transcriptional level. They participate in a wide variety of biological processes, including apoptosis, proliferation and metastasis. The aberrant expression of miRNAs has been found to play an important role in many cancers.

Percutaneous vertebroplasty combined with interstitial implantation of 125I seeds in banna mini-pigs.

Background: Although brachytherapy is one of the most effective ways to treat metastatic spinal tumor with little damage to surrounding healthy tissue, it may cause radiation myelopathy if an overdose occurs. Establishing a valuable animal model can help to find a method to overcome its complications. In the current study, we set up a banna mini-pig model to mimic percutaneous vertebroplasty with 125I seed implantation.