Publications by authors named "Yanjiao Hou"
Article Synopsis
- Non-small cell lung cancer (NSCLC) shows poor response to traditional therapies, leading researchers to explore the impact of MHC I expression on immunotherapy effectiveness.
- Low-dose Suberoylanilide hydroxamic acid (SAHA), an HDAC inhibitor, was found to enhance CD8 T cell activity by increasing MHC I levels in NSCLC cells without harming cell viability.
- The study demonstrated that high MHC I levels stimulated specific CD8 T cells, improving their activation and antitumor effects, implicating potential strategies for NSCLC treatment enhancement through IFI modulation.
Background: This study aimed to investigate the neural substrates of processing depression emotion in premenstrual syndrome (PMS) and healthy subjects of college students using blood oxygenation level-dependent functional magnetic resonance imaging (BOLD-fMRI).
Methods: During BOLD-fMRI scanning, 13 PMS patients and 15 healthy controls (HC) performed a picture visual stimulation task during luteal and follicular phases, in which participants and HC were asked to see pictures containing depression and non-depression emotions. Simultaneously, self-rating depression scales (SDS) were employed to evaluate the emotional status of participants.
Aims: Non-small cell lung cancer (NSCLC) is considered a highly fatal tumor. Importantly, angiogenesis is critical for tumor progression. Long non-coding RNAs (lncRNAs), which are untranslatable, control cell functions through different pathways.
View Article and Find Full Text PDFAlthough oxaliplatin serves as one of the first-line drugs prescribed for treating colorectal cancer (CRC), the therapeutic effect is disappointing due to drug resistance. So far, the molecular mechanisms mediating oxaliplatin resistance remain unclear. In this study, we found the chemoresistance in oxaliplatin-resistant HCT116 cells (HCT116/OXA) was mediated by the upregulation of ERCC1 expression.
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