Chronic disease associated with bullous pemphigoid risk: A systematic review and meta-analysis.

Background: Bullous pemphigoid (BP) is a chronic autoimmune blistering disease prevalent in the elderly, often accompanied by renal comorbidities. Immune dysregulation can lead to secondary BP and increased mortality rates in those already diagnosed.

Methods: A literature review identified studies on the association between kidney disease and other comorbidities with BP.

Implantation of a permanent pacemaker following orthotopic heart transplantation: a systematic review and meta-analysis.

Background: Orthotopic heart transplant (OHT) is among the final armamentariums for end-stage heart disease. Many patients who have had OHT require a post-transplant permanent pacemaker (PPM) implantation due to an abnormal conduction system. We aimed to evaluate the risk of mortality and acute rejection in patients with OHT who had received PPM compared to patients without PPM and to determine predictors for PPM placement in this population.