Publications by authors named "Yaning Li"
Brainstem opioid peptidergic neurons regulate cough reflexes in mice.
Innovation (Camb)
November 2024
Article Synopsis
- - Coughing serves as a protective reflex to remove harmful substances from the airway, but how the brain processes this reflex isn't fully understood.
- - Researchers created a method to quantitatively assess cough-like reflexes in mice and discovered that specific neurons in the nucleus of the solitary tract (NTS) play a critical role in these reflexes.
- - The activation of these NTS neurons, which receive signals from vagal sensory neurons, triggers respiratory responses similar to coughing, highlighting their importance in initiating cough-like reflexes via a specific neural pathway to the cough center in the brain.
Article Synopsis
Article Synopsis
GeneCompass: deciphering universal gene regulatory mechanisms with a knowledge-informed cross-species foundation model.
Xiaodong Yang Guole Liu Guihai Feng Dechao Bu Pengfei Wang Zhongming Liang Yaning Li Zheng Li Yana Liu Wenhao Liu Cong Li Ao Li Lina Cui Handong Li Liqun Zhong Fei Li Jing Liu Xin Li
Cell Res
December 2024
Article Synopsis
- Understanding gene regulation across different species can greatly enhance our knowledge of life and improve clinical applications, but traditional research limits itself by focusing on single organisms without cross-species integration.
- This study created a massive dataset of over 101 million single-cell transcriptomes from humans and mice, leading to the development of an AI model called GeneCompass, which incorporates various biological knowledge to improve gene regulation understanding.
- GeneCompass not only performed better than existing models in single-species tasks but also facilitated new research avenues across species, identifying gene factors that can influence human embryonic stem cell differentiation into specific cell types.
Strain-tunable electronic anisotropy of the AlSb double-layer honeycomb structure.
Phys Chem Chem Phys
October 2024
Two-dimensional (2D) materials show promising applications in nanoelectronic devices due to their excellent physical and chemical properties, large specific surface area, and good flexibility. 2D AlSb, a representative of a new class of two-dimensional materials with a double-layer honeycomb (DLHC) structure was recently obtained in experiments and was reported to be a direct band gap semiconductor. Strain engineering is an effective way of tuning the properties of 2D materials.
View Article and Find Full Text PDFArticle Synopsis
- - The study examines how two nitro explosives, LLM-105 and NQ, affect the thermal decomposition of DNTF by simulating their interactions at various temperatures.
- - Results show that the presence of LLM-105 and NQ alters DNTF's decomposition mechanism, leading to different reaction pathways and the stability of products compared to pure DNTF systems.
- - The analysis utilizes advanced computational methods (CP2K and GFNI-xTB) to accurately model and calculate the behaviors of the DNTF mixtures, revealing significant differences in how these materials break down under heat.