Publications by authors named "Yanina Nikolaus"
Article Synopsis
- Cytology-histology correlation (CHC) is crucial for quality assurance in cytology labs, ensuring effective patient treatment and serving as an educational tool for lab staff.
- In a study analyzing cervical Pap smears (CPs) and cervical biopsies (CBs) from 2019, results showed that CPs and CBs conducted at the same institution had significantly fewer disagreements compared to those done at different institutions.
- The findings suggest that to improve CHC accuracy, it's preferable for CPs and CBs to be performed at the same facility, and if not, a review of CPs by the biopsy-performing institution should be recommended.
Objective: Mutations in the EIF1AX gene have been recently detected in a small percentage of benign and malignant thyroid lesions. We sought to investigate the prevalence and clinical significance of EIF1AX mutations and co-mutations in cytologically indeterminate thyroid nodules at our institution.
Materials And Methods: A 5-year retrospective analysis was performed on thyroid nodules with a cytologic diagnosis of Bethesda category III or IV, which had undergone testing by our in-house next generation sequencing panel.