Effect of different modes of administration of esketamine combined with supraclavicular brachial plexus block on the incidence of rebound pain after upper limb fracture surgery: study protocol for a single-centre, double-blinded, randomised controlled trial.

Background: Supraclavicular brachial plexus block (SCB) is a common regional analgesic technique for upper limb fracture surgery, but it often leads to rebound pain. Our primary aim is to determine whether different administration methods of esketamine can reduce rebound pain in patients undergoing SCB for upper limb fracture surgery.

Methods/design: This study is designed as a single-centre, double-blinded, prospective, randomised controlled trial.

Atomically Dispersed Cobalt Anchored on Hollow Tubular Carbon Nitride Mediates Direct Electron Transfer and Oxygen-Related Active Species Path for Activation of Permonosulfate.

Atomically dispersed catalysts anchored on nitrogen-rich substrates present promising application potential for the persulfate-based advanced oxidation process. Nevertheless, efficient activation efficiency and a clear activated mechanism of persulfate remain challenging in carbon nitride-based single-atom catalysts (SACs). To these, combined with the regulation strategy of metal-ligand section and carrier's architecture, an atomically dispersed Co single-atom catalyst anchored on regular hollow tubular carbon nitride (Co/TCN SAC) herein was devised and utilized to activate permonosulfate.

Characteristics of the top 100 cited original studies on extracorporeal membrane oxygenation: a bibliometric analysis.

Background: Extracorporeal membrane oxygenation (ECMO) has been widely used as a life support for different kinds of acute cardiopulmonary dysfunction. The present study aimed at presenting the global trend of the top 100 cited original studies related to ECMO.

Methods: Bibliometric analysis was the primary methodology for this study.

Emerging Trends and Hot Topics of Non-Invasive Electroencephalography Research in the Elderly: A Bibliometric Analysis from 2014 to 2023.

Background: Electroencephalography (EEG) has been rapidly developed and is widely used in both clinical and scientific fields. Original studies on non-invasive EEG in the elderly have been of great importance owing to the global aging trend. The present study aimed to provide a bibliometric overview on current status and trends in this research field.

Role of lumbar puncture level on the onset of epidural labor analgesia: a randomized controlled trial.

Objective: To compare the speed of achieving painless uterine contractions in parturients undergoing epidural analgesia at different lumbar puncture levels.

Methods: This study is a randomized controlled trial at a tertiary A hospital with a history of over 80 years in Sichuan Province, China. Parturients aged 22-40 years old scheduled for vaginal delivery under epidural analgesia were recruited.

Schottky Junctions with Bi@BiMoO Core-Shell Photocatalysts toward High-Efficiency Solar N-to-Ammonnia Conversion in Aqueous Phase.

The photocatalytic nitrogen reduction reaction (NRR) in aqueous solution is a green and sustainable strategy for ammonia production. Nonetheless, the efficiency of the process still has a wide gap compared to that of the Haber-Bosch one due to the difficulty of N activation and the quick recombination of photo-generated carriers. Herein, a core-shell Bi@BiMoO microsphere through constructing Schottky junctions has been explored as a robust photocatalyst toward N reduction to NH.

Photothermal Synergistic Catalysis over Defective ZnInS for CO Fixation.

Carbon dioxide (CO) cycloaddition not only produces highly valued cyclic carbonate but also utilizes CO as C1 resources with 100% atomic efficiency. However, traditional catalytic routes still suffer from inferior catalytic efficiency and harsh reaction conditions. Developing multienergy-field catalytic technology with expected efficiency offers great opportunity for satisfied yield under mild conditions.

Mineralization versus polymerization pathways in heterogeneous Fenton-like reactions.

Fenton reaction has been widespread application in water purification due to the excellent oxidation performances. However, the poor cycle efficiency of Fe(III)/Fe(II) is one of the biggest bottlenecks. In this study, graphite (GP) was used as a green carbon catalyst to accelerate Fenton-like (HO/Fe and persulfate/Fe) reactions by promoting ferric ion reduction and intensifying diverse peroxide activation pathways.

The Effects of Different Puncture Points on Labor Analgesia Onset: Study Protocol for a Randomized Controlled Trial.

Purpose: Parturients suffer severe pain during the stages of labor, especially the first and second. Epidural anesthesia is an effective method to alleviate labor pain. L2-3, L3-4 and L4-5 spaces have been reported to be the recommendable puncture points owing to the adequate analgesia effect and high safety.

Thermodynamic and Kinetic Behaviors of Persulfate-Based Electron-Transfer Regime in Carbocatalysis.

A carbon-based advanced oxidation process is featured for the nonradical electron-transfer pathway (ETP) from electron-donating organic compounds to activated persulfate complexes, enabling it as a green technology for the selective oxidation of organic pollutants in complex water environments. However, the thermodynamic and kinetic behaviors of the nonradical electron-transfer regime had been ambiguous due to a neglect of the influence of pH on the mechanisms. In this study, three kinds of organic pollutants were divided in the carbon-based ETP regime: (i) physio-adsorption, (ii) adsorption-dominated ETP (oxidation rate slightly surpasses adsorption rate), and (iii) oxidation-dominated ETP (oxidation rate outpaces the adsorption rate).

BiOI/BiMoO p-n Junction to Enhance Visible Light Photocatalytic Activity toward Environmental Remediation.

Photocatalytic degradation of organic pollutants via semiconductors with high visible light response and effective carrier separation is an economical and green route to greatly achieve environmental remediation. Herein, an efficient BiOI/BiMoO p-n heterojunction was in situ fabricated through hydrothermal method by substituting MoO species for I ions. The characteristic p-n heterojunction exhibited a strongly enhanced visible light responsive absorption from 500 to 700 nm owing to the narrow band gap of BiOI and a greatly effective separation of photoexcited carriers because of the built-in electric field on the interface between BiOI and BiMoO.

Nanostructured conversion-type anode materials of metal-organic framework-derived spinel XMnO (X = Zn, Co, Cu, Ni) to boost lithium storage.

Bimetallic spinel transition metal oxides play a major part in actualizing eco-friendly electrochemical energy storage systems (ESSs). However, structural precariousness and low electrochemical capacitance restrict their actual implementation in lithium-ion batteries (LIBs). To address these demerits, the sacrificial template approach has been considered as a prospective way to strengthen electrochemical stability and rate performance.

Mu-opioid receptor alleviated ferroptosis in hepatic ischemia-reperfusion injury via the HIF-1α/ axis.

Ferroptosis is the ideal therapeutic target for hepatic ischemia and reperfusion injury (HIRI). The μ opioid receptor (MOR) is associated with ferroptosis in HIRI. We aimed to determine the ferroptosis-related therapeutic mechanism of MOR in HIRI.

Enhanced Photo-Assisted Fenton Degradation of Antibiotics over Iron-Doped Bi-Rich Bismuth Oxybromide Photocatalyst.

Herein, combining photocatalysis and Fenton oxidation, a photo-assisted Fenton system was conducted using Fe-doped BiOBr as a highly efficient photocatalyst to realize the complete degradation of Tetracycline antibiotics under visible light. It has been observed that the optimized photocatalyst 5%Fe-doped BiOBr exhibits a degradation efficiency of 100% for Tetracycline with HO after 3 h visible-light irradiation, while a degradation percentage of 59.8% over the same photocatalyst and 46.

Silencing lncRNA KCNQ1OT1 reduced hepatic ischemia reperfusion injury-induced pyroptosis by regulating miR-142a-3p/HMGB1 axis.

Background: Based on pre-existing evidence, KCNQ1OT1 has been pointed out to be closely related to myocardial and cerebral ischemia reperfusion injury diseases. Herein, the objective of our study is to probe into the potential function as well as the underlying mechanism of KCNQ1OT1 on hepatic ischemia reperfusion injury (HIRI).

Methods: Using C57BL/6 J mice and primary mouse hepatocytes were conducted to establish HIRI model in vivo and in vitro.

Electron-transfer-based peroxymonosulfate activation on defect-rich carbon nanotubes: Understanding the substituent effect on the selective oxidation of phenols.

Nanocarbon-based persulfate oxidation technologies are promising for green elimination of phenolic pollutants. Previous studies revealed the electron transfer via defective carbon nanotube (CNTs) for selective oxidation of various phenols. However, an underlying relationship between the molecular structure of phenols and the selectivity of electron transfer-induced oxidation has not been well understood.

Preparation, Characterization and Application of Epitaxial Grown BiOBr (110) Film on ZnFeO Surface with Enhanced Photocatalytic Fenton Oxidation Properties.

A novel BiOBr photocatalyst was epitaxially grown in situ onto the surface of ZnFeO, a ferroelectric material with a strong polarization effect. The formatted BiOBr/ZnFeO composite (BOB/ZFO) showed excellent photocatalytic degradation performance of tetracycline antibiotics (TCs). One of the composites with ZnFeO content of 10% (BOB/ZFO-10) showed the best properties; the degradation efficiency of TCs upon visible light irradiation for 180 min was 99.

Octreotide ameliorates hepatic ischemia-reperfusion injury through SNHG12/TAF15-mediated Sirt1 stabilization and YAP1 transcription.

Background: Hepatic ischemia-reperfusion (HIR) injury is a pathological condition initiated by interrupted hepatic blood supply and exaggerated after reperfusion, which is one of the most lethal risks in liver transplantation and other liver surgeries. We aimed to investigate the protective mechanism of octreotide (Oct) against HIR injury.

Methods: The function of Oct was evaluated in the in vivo mouse model of HIR injury.

Vertical tank capacity measurement based on Monte Carlo method.

Vertical tanks are commonly used appliances for liquids, and its capacity is very important for quantitative liquid ratio and liquid trade. In order to measure the capacity of vertical tanks more conveniently, this paper proposes a vertical tank capacity measurement method based on Monte Carlo Method. The method arranges a plurality of sensor points on the inner surface of the tank, and then performs Monte Carlo tests by generating a large number of random sample points, and finally calculates the capacity by counting the sample points that meet the criterion.

Sufentanil postoperative analgesia reduce the increase of T helper 17 (Th17) cells and FoxP3 regulatory T (Treg) cells in rat hepatocellular carcinoma surgical model: A randomised animal study.

Background: Surgery-related pain and opioids might exacerbate immune defenses in immunocompromised cancer patients which might affect postoperativd overall survival. Sufentanil is a good postoperative pain control drug,the present study aimed to figure out whether it effect T cell immunity in rat hepatocellular carcinoma surgical model.

Methods: A rat hepatocellular carcinoma (HCC) models was established by N-nitrosodiethylamine.

Construction of an Inducible CRISPR/Cas9 System for CXCR4 Gene and Demonstration of its Effects on MKN-45 Cells.

The CRISPR/Cas9 system is an effective tool for gene editing. However, this conventional expression system cannot control the timing of gene editing and does not utilize resistance screening markers. Therefore, carrying out CRISPR/Cas9 experiments is extremely inconvenient.

Visible-near-infrared-responsive g-CNH reduced decatungstate with excellent performance for photocatalytic removal of petroleum hydrocarbon.

The development of photocatalysts making full use of natural light sources is highly desired for the remediation of marine oil spill pollution, which is full of challenges. Herein, we demonstrate a well-defined visible-near-infrared-responsive g-CNH reduced decatungstate charge-transfer salt (RCD-CTS), which possess efficient light-absorption ability ranging from visible light to the near infrared region. The RCD-CTS photocatalyst exhibits excellent performance for photocatalytic removal of petroleum hydrocarbon.

The stromal cell-derived factor 1/C-X-C chemokine receptor type 4 axis is important in neutrophil migration caused by cardiopulmonary bypass in children.

Objectives: Acute lung injury caused by cardiopulmonary bypass (CPB) is characterized by massive neutrophil migration to the lungs. Neutrophil migration may be closely related to stromal cell-derived factor 1 (SDF-1)/C-X-C chemokine receptor Type 4 (CXCR4) axis activation, which plays an essential role in modulating the trafficking of neutrophils. We investigated the changes in the expression of SDF-1/CXCR4 axis components before and after CPB as well as the role of the axis in driving the migration of neutrophils in patients with congenital heart disease.

Roux-en-Y gastric bypass improves glucose homeostasis, reduces oxidative stress and inflammation in livers of obese rats and in Kupffer cells via an AMPK-dependent pathway.

Background: Oxidative stress and inflammation are implicated in the pathogenesis of steatohepatitis. We hypothesize that Roux-en-Y gastric bypass reduces oxidative stress and inflammation in the liver of obese rats via activation of AMPK-α.

Methods: Obese Sprague-Dawley male rats underwent either sham operation or Roux-en-Y gastric bypass.