Publications by authors named "Yanhao Chu"

Introduction And Aims: Finite element analysis (FEA) is an incrementally practical and precise tool for the prediction of stress effects on different tissue structures and has therefore interested dental researchers for decades. This bibliometric and visualized study was aimed to assess the research progress related to FEA in the dental sciences in terms of research trends and frontiers.

Methods: The articles about FEA studies in this field during 1999 to 2024 were obtained from Web of Science Core Collection.

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Metasurfaces, composed of sub-wavelength structures, have a powerful capability to manipulate light propagations. However, metasurfaces usually work either in pure reflection mode or pure transmission mode. Achieving full-space manipulation of light at will in the optical region is still challenging.

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Correction of chromatic aberration is an important issue in color imaging and display. However, realizing broadband achromatic imaging by a singlet lens with high comprehensive performance still remains challenging, though many achromatic flat lenses have been reported recently. Here, we propose a deep-learning-enhanced singlet planar imaging system, implemented by a 3 mm-diameter achromatic flat lens, to achieve relatively high-quality achromatic imaging in the visible.

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Article Synopsis
  • Metasurfaces can enhance lenses by eliminating color distortions (chromaticity) when paired with traditional refractive lenses, but often leave some residual distortion due to limitations in the available metasurface designs.
  • The authors propose a new design method that combines both the refractive elements and metasurface as a single unit to create a large-scale, achromatic hybrid lens without any residual dispersion.
  • A successful prototype of this lens is demonstrated at a centimeter scale, showcasing improved performance compared to previous lens designs, providing valuable insights for future high-quality achromatic metalenses.
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Introduction: Clinical studies have revealed the existence of circadian rhythms in pain intensity and treatment response for chronic pain, including orofacial pain. The circadian clock genes in the peripheral ganglia are involved in pain information transmission by modulating the synthesis of pain mediators. However, the expression and distribution of clock genes and pain-related genes in different cell types within the trigeminal ganglion, the primary station of orofacial sensory transmission, are not yet fully understood.

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Odontoblastic differentiation of human dental pulp stem cells (hDPSCs) is crucial for the intricate formation and repair processes in dental pulp. Until now, the literature is not able to demonstrate the role of ubiquitination in the odontoblastic differentiation of hDPSCs. This study investigated the role of F-box-only protein 32 (FBXO32), an E3 ligase, in the odontoblastic differentiation of hDPSCs.

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Satellite glial cells (SGCs) play an important role in regulating the function of trigeminal ganglion (TG) neurons. Multiple mediators are involved in the bidirectional communication between SGCs and neurons in different physiological and pathological states. However, molecular insights into the transcript characteristics of SGCs are limited.

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Article Synopsis
  • * Twenty-five patients, aged 15 to 29, were analyzed to assess factors like midpalatal suture density and maturation, finding that older age negatively impacted bone and alveolar expansion.
  • * Results suggest that age, midpalatal suture maturation, and suture density should be considered for optimizing MARPE treatment outcomes.
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Background: The sympathetic nervous system (SNS) is suggested to be involved in some forms of pain, but the mechanisms of which are incompletely known. Moreover, there is a lack of information on the regulatory role of the SNS on macrophages in sensory ganglion, which plays an important role in pain development. The present study aims to investigate the effects of the SNS on orofacial inflammatory pain and examine, if any, how the SNS influences trigeminal ganglion (TG) macrophage responses.

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Trigeminal ganglion (TG) is the first station of sensory pathways in the orofacial region. The TG neurons communicate with satellite glial cells (SGCs), macrophages and other cells forming a functional unit that is responsible for processing of orofacial sensory information. Purinergic signaling, one of the most widespread autocrine and paracrine pathways, plays a crucial role in intercellular communication.

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Protein ubiquitination is a precisely controlled enzymatic cascade reaction belonging to the post-translational modification of proteins. In this process, E3 ligases catalyze the binding of ubiquitin (Ub) to protein substrates and define specificity. The neuronally expressed developmentally down-regulated 4 (NEDD4) subfamily, belonging to the homology to E6APC terminus (HECT) class of E3 ligases, has recently emerged as an essential determinant of multiple cellular processes in different tissues, including bone and tooth.

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Orofacial inflammation leads to transcriptional alterations in trigeminal ganglion (TG) neurons. However, diverse alterations and regulatory mechanisms following orofacial inflammatory pain in different types of TG neurons remain unclear. Here, orofacial inflammation was induced by injection of complete Freund's adjuvant (CFA) in mice.

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The circadian clock is a biochemical oscillator that is synchronized with solar time. Normal circadian rhythms are necessary for many physiological functions. Circadian rhythms have also been linked with many physiological functions, several clinical symptoms, and diseases.

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Background: Because racial discrepancies in dental characteristics are known to exist, designing preadjusted appliances according to racial normal occlusion data would be expected to improve treatment results. However, whether modifications based on racial characteristics can improve treatment outcomes in the clinic remains to be investigated.

Methods: To study the influence of prescription type on treatment outcomes, 91 patients treated with Chinese or Roth prescription appliances were selected as an initial sample.

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The purpose of this study is to provide a forensic reference data about estimating chronologic age by evaluating the third molar mineralization of Han in central southern China. The mineralization degree of third molars was assessed by Demirjian's classification with modification for 2519 digital orthopantomograms (1190 males, 1329 females; age 8-23 years). The mean ages of the initial mineralization and the crown completion of third molars were around 9.

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