Analysis of drivers' deceleration behavior based on naturalistic driving data.

As one of the bases for designing a humanlike brake control system for the intelligent vehicle, drivers' deceleration behavior needs to be understood. There are two modes for drivers' deceleration behavior: (i) brake pedal input, by applying brake system to reduce the speed; (ii) no pedal input, by releasing the accelerator pedal without pressing the brake pedal, thus decelerating by naturalistic driving resistance. The deceleration behavior that drivers choose to press the brake pedal has been investigated in previous studies.

Enantiospecific determination of arotinolol in rat plasma by LC-MS/MS: application to a stereoselective pharmacokinetic study.

A highly sensitive and selective liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed and fully validated for quantification of arotinolol enantiomers in rat plasma using haloperidol as the internal standard. After solid phase extraction of 50.0 μL rat plasma in 96 well plate, a baseline resolution of arotinolol enantiomers was achieved on a CHIRALPAK AD-H column using the mobile phase of n-hexane and ethanol in 0.

Rapid and sensitive liquid chromatography with tandem mass spectrometry method for the simultaneous determination of 11 major components of Yuanhu-Baizhi herb-pair in rat perfusion fluids.

A rapid and sensitive liquid chromatography with tandem mass spectrometry method has been developed and validated for the simultaneous quantification of 11 major compounds in Yuanhu-Bazhi herb-pair from a rat intestinal perfusion experiment, including eight alkaloids and three coumarins using diazepam as the internal standard. The analysis was performed on an Agilent Poroshell 120EC-C18 column using a gradient elution of acetonitrile/H2 O with 0.0015% formic acid and 2 mM ammonium formate buffer additive (pH 4.