Publications by authors named "Yangzhong Guo"
Article Synopsis
- * Fungal metabolites may contribute to cancer onset, and antifungal treatments can interact with cancer therapies, potentially influencing their effectiveness and side effects.
- * The study suggests that analyzing fungal profiles in patients (mycobiota) could serve as useful diagnostic tools, while exploring new ways to adjust these fungal communities may enhance cancer treatment outcomes.
A variety of abnormal epithelial cells and immature and mature immune cells in thymic epithelial tumors (TETs) affect histopathological features, the degree of malignancy, and the response to treatment. Here, gene expression, trajectory inference, and T cell antigen receptor (TCR)-based lineage tracking are profiled in TETs at single-cell resolution. An original subpopulation of KRT14 progenitor cells with a spindle cell phenotype is shown.
View Article and Find Full Text PDFBackground: Lactate dehydrogenase (LDH) has emerged as a promising biomarker for cancer. However, the current understanding of LDH and circulating LDH expression in thymic epithelial tumour (TET) is lacking.
Methods: A comprehensive literature review and meta-analysis were performed to evaluate the clinical significance of circulating LDH levels in patients with TET.
Background: The advantages of radiotherapy for head and neck squamous cell carcinoma (HNSCC) depend on the radiation sensitivity of the patient. Here, we established and verified radiological factor-related gene signature and built a prognostic risk model to predict whether radiotherapy would be beneficial.
Methods: Data from The Cancer Genome Atlas, Gene Expression Omnibus, and RadAtlas databases were subjected to LASSO regression, univariate COX regression, and multivariate COX regression analyses to integrate genomic and clinical information from patients with HNSCC.