Publications by authors named "Yangxue Sun"

Objectives: Coronary artery bypass grafting (CABG) is often performed alongside type A aortic dissection (TAAD) repair. However, the association between concomitant CABG and the clinical outcomes of TAAD repair remains uncertain.

Methods: This study included 1,002 consecutive TAAD patients who underwent total aortic arch replacement (TAR) with frozen elephant trunk (FET) from June 2019 to January 2024.

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Article Synopsis
  • The study aimed to compare the surgical performance of a new large-diameter composite polycarbonate polyurethane graft to a traditional polyester graft in patients undergoing thoracic aortic prosthesis replacement.
  • A review of 14 patients from 2016 to 2021 showed that the polycarbonate polyurethane graft group had significantly shorter operation times and less postoperative drainage and hospital stays compared to the polyester graft group.
  • The findings suggest that the new graft has promising properties, but further testing in a larger, multi-center trial is necessary for confirmation.
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Background: For acute type A aortic dissection involving the aortic root with root diameter no more than 45 mm, there are various aortic root repair techniques. In this study, a novel surgical technique using a pericardial autograft for aortic root repair was introduced. We described its surgical steps in detail and compare its clinical outcomes with direct suture technique.

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  • The study aimed to evaluate various treatment strategies for proximal isolated subclavian artery aneurysms (PISAAs) at a specific institution over a six-year period.
  • It involved a retrospective analysis of 15 patients who underwent different types of procedures, including cervical reconstruction, thoracotomy reconstruction, and endovascular treatment, with a focus on success rates and postoperative outcomes.
  • Results showed high success rates for cervical and thoracotomy reconstructions but highlighted longer operation times and greater blood loss in thoracotomy; endovascular treatment had lower reconstruction rates for related arteries but fewer complications post-surgery.
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Background: This study was designed to evaluate the clinical outcomes of our modified cuff wrapping Bentall (M-Bentall) procedure, which uses a cuff wrapping technique with remnant aortic root tissue.

Methods: From July 2017 to December 2021, a total of 136 patients met the inclusion criteria for this study. Among them, patients who underwent the modified Bentall procedure using the cuff wrapping technique were included in the M-Bentall group (n=46), while patients who underwent the classic Bentall (C-Bentall) procedure were categorized into the C-Bentall group (n=90).

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Background: The outcomes after septal myectomy in young children and infants with hypertrophic obstructive cardiomyopathy (HOCM) are not clear. The study sought to report the outcomes after septal myectomy in young children and infants and identify the mechanisms of residual or recurrent obstruction after surgery.

Methods: The authors performed an observational cohort study of children and infants under the age of 14 who underwent septal myectomy for HCOM from January 2013 to December 2020.

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Article Synopsis
  • The study examined factors influencing the outcomes of 148 children with pulmonary valve atresia treated with balloon dilation, finding that 138 survived over a 5-year period and 10 died.
  • Statistical analysis revealed significant factors affecting prognosis, including height, weight, body surface area, oxygen saturation, and the degree of tricuspid regurgitation.
  • A nomogram prediction model was developed to help clinicians assess prognosis, showing a good fit with a C-index of 0.667, providing a tool for identifying cases at higher risk for poor outcomes.
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Thoracic aortic pseudoaneurysm caused by Brucella melitensis is extremely rare with extremely few cases reported to date. Herein, we present the case of a 65 year-old man with a huge pseudoaneurysm of the proximal descending thoracic aorta, involving the left subclavian artery and distal arch. Surgery was performed to replace the proximal descending aorta with a self-made bovine pericardial duct and the left subclavian artery with a 10 mm artificial vessel under deep hypothermic circulatory arrest; the patient recovered uneventfully.

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Background: The recommendation of the European Society for Vascular Surgery (ESVS) is that vertebral revascularization combined with ipsilateral CEA (carotid endarterectomy) should not be performed in the same operation. ESVS believes that vertebral revascularization combined with ipsilateral CEA increases perioperative death/stroke rates. In our opinion, revascularization of the first segment of vertebral artery (V1) combined with ipsilateral CEA is safe compared to vertebral V1 revascularization in the perioperative period.

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The most commonly used arterial cannulation sites for type A aortic dissection are right axillary artery, femoral artery and both. Direct central aortic cannulation has also been reported. In rare cases, it is extremely difficult to choose an arterial cannulation site for type A aortic dissection due to involvement of the right axillary and both femoral arteries.

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Objective: Several surgical techniques for repair of a complete atrioventricular septal defect have been developed. However, the postoperative complications with these methods may lead to reoperation during follow-up. The aim of this report is to share our experience with a modified surgical technique for complete atrioventricular septal defect that has anatomic advantages postoperatively and could reduce the reoperation rate.

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Noonan syndrome (NS) is a genetic syndrome causing obstructive hypertrophic cardiomyopathy (HCM) in infants. Studies of cardiac surgery in pediatric HCM patients with NS (NS-HCM) are lacking. We aim to characterize the early disease course of young NS-HCM patients before adolescence and assess their complications and survival condition after septal myectomy.

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Background: The most common materials of artificial blood vessels are polyethylene terephthalate and polytetrafluoroethylene. But polycarbonate polyurethane (PCU) is an ideal material for vascular prostheses because of their excellent characteristics. As far as we know, our artificial blood vessel is the first type of hybrid PCU/polyester three-layered large-diameter artificial blood vessel in the world.

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Background: Cyanotic congenital heart disease (CCHD) is one of the most common birth anomalies, in which chronic hypoxia is the basic pathophysiological process.

Methods: To investigate the heart's metabolic remodeling to hypoxia, we performed an untargeted metabolomic analysis of cardiac tissue from 20 CCHD patients and 15 patients with acyanotic congenital heart disease (ACHD).

Results: A total of 71 (63%) metabolites from 113 detected substances in cardiac tissue differed between the CCHD and ACHD groups.

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Background: This study investigated a 2-stage arterial switch operation (ASO) to treat transposition of the great arteries (TGA) with intact ventricular septum (TGA-IVS) in late referral patients.

Methods: We retrospectively analyzed patients with TGA-IVS or TGA with restricted ventricular septal defects who had undergone 2-stage ASO at our institution from February 2007 to August 2018. Included were 41 patients: 21 (51.

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