CRISPR-Cas13 in malaria parasite: Diagnosis and prospective gene function identification.

Malaria caused by is still a serious public health problem. Genomic editing is essential to understand parasite biology, elucidate mechanical pathways, uncover gene functions, identify novel therapeutic targets, and develop clinical diagnostic tools. Recent advances have seen the development of genomic diagnostic technologies and the emergence of genetic manipulation toolbox comprising a host of several systems for editing the genome of at the DNA, RNA, and protein level.