Validation of a system for automatic quantitative analysis of laboratory mice behavior based on locomotor pose.

Automatic recognition and accurate quantitative analysis of rodent behavior play an important role in brain neuroscience, pharmacological and toxicological. Currently, most behavior recognition systems used in experiments mainly focus on the indirect measurements of animal movement trajectories, while neglecting the changes of animal body pose that can indicate more psychological factors. Thus, this paper developed and validated an hourglass network-based behavioral quantification system (HNBQ), which uses a combination of body pose and movement parameters to quantify the activity of mice in an enclosed experimental chamber.

Enhancing methanogenesis from anaerobic digestion of propionate with addition of Fe oxides supported on conductive carbon cloth.

In this study, a FeO supported on conductive carbon cloth (FC) was prepared and supplemented into anaerobic digestion reactors to improve propionate degradation. In the FC-supplemented reactors, the cumulative methane production and propionate degradation increased by 15.4% and 19.

Glucagon secretion is increased in patients with Type 2 diabetic nephropathy.

Aims: Currently little is known about the relationship between renal function, albuminuria and glucagon; we analyzed the secretion of glucagon (GLA) and C-peptide in Type 2 diabetic patients with different degrees of nephropathy.

Methods: 357 patients with Type 2 diabetes including 119 cases without nephropathy and 238 cases with nephropathy were divided into four groups according to the stages of diabetic nephropathy. Patients with diabetic nephropathy were further classified according to the level of estimated glomerular filtration rate (eGFR).

[Correlation study between obesity and dawn phenomenon in patients with type 2 diabetes].

Objective: To investigate the correlation between the frequency of dawn phenomenon and obesity in patients with type 2 diabetes.

Methods: This study was conducted in 98 patients with type 2 diabetes admitted to the Metabolic Disease Hospital of Tianjin Medical University from 2011 to 2014. The subjects were divided into 3 groups according to BMI: the normal weight (BMI 18.

[Association between retinopathy and sleep disorder in patients with type 2 diabetes mellitus].

Objective: To explore the association between retinopathy and sleep disorder in patients with type 2 diabetes mellitus (T2DM).

Methods: A total of 440 patients with T2DM treated from July 2011 to July 2013 in Metabolic Disease Hospital of Tianjin Medical University were divided into 2 groups according to Pittsburgh Sleep Quality Index: non-sleep disorder group (258 cases) and sleep disorder group (182 cases). Biochemical parameters including hepatorenal function, blood lipids, glycosylated hemoglobin (HbA1c), fructosamine and hemorrheology were detected.

[Association between sleep disorder and osteoporosis in elderly female patients with type 2 diabetes mellitus].

Objective: To explore the association between sleep disorder and osteoporosis in elderly female patients with type 2 diabetes mellitus (T2DM).

Methods: A total of 536 elderly female T2DM patients from July 2011 to July 2014 were divided into two groups of patients without sleep disorder and those with sleep disorder based upon the Pittsburgh Sleep Quality Index. The bone mineral density of femoral neck, Wards triangle, greater trochanter and lumbar spines (L2-L4) were measured by dual-energy X-ray absorptiometry.

[Association between sleep disorders and dawn phenomenon in patients with type 2 diabetes mellitus].

Objective: To explore the association between sleep disorders and dawn phenomenon in patients with type 2 diabetes mellitus (T2DM).

Methods: From July 2011 to July 2014 at Metabolic Disease Hospital, Tianjin Medical University, 316 T2DM patients on continuous glucose monitoring were divided into two groups according to the Pittsburgh Sleep Quality Index, i.e.

Effects of 24-week treatment with acarbose on glucagon-like peptide 1 in newly diagnosed type 2 diabetic patients: a preliminary report.

Background: Treatment with the alpha-glucosidase inhibitor (AGI) acarbose is associated with a significant reduction the risk of cardiovascular events. However, the underlying mechanisms of this effect are unclear. AGIs were recently suggested to participate in stimulating glucagon-like peptide 1 (GLP-1) secretion.

Predicting the risk of secondary lung malignancies associated with whole-breast radiation therapy.

Purpose: The risk of secondary lung malignancy (SLM) is a significant concern for women treated with whole-breast radiation therapy after breast-conserving surgery for early-stage breast cancer. In this study, a biologically based secondary malignancy model was used to quantify the risk of secondary lung malignancies (SLMs) associated with several common methods of delivering whole-breast radiation therapy (RT).

Methods And Materials: Both supine and prone computed tomography simulations of 15 women with early breast cancer were used to generate standard fractionated and hypofractionated whole-breast RT treatment plans for each patient.