Publications by authors named "Yangtian Ye"
Article Synopsis
- Metal-organic frameworks (MOFs) are gaining attention for enzyme immobilization due to their high surface areas and specific pore structures, but most research has focused on model enzymes rather than practical applications.
- The study explores immobilizing the ketoreductase KmCR2 onto zeolitic imidazolate framework (ZIF) using a controlled co-precipitation method, resulting in a mostly amorphous biocomposite (KmCR2@ZIF).
- The KmCR2@ZIF demonstrated enhanced thermal and storage stability compared to the free enzyme and successfully catalyzed the stereoselective reduction of diarylmethanones with high conversion rates and optical purities, while retaining its unique stereospecificity.
Background: Several studies showed that androgen deprivation therapy (ADT) plus local treatment of prostate could improve metastatic prostate cancer (mPCa) patients' survival. To date there are few studies analyzed the value of prostate cryoablation in mPCa. The objective of our analysis is to evaluate the oncological results and clinical value of prostate cryoablation combined with ADT compared with ADT alone in newly diagnosed mPCa patients.
View Article and Find Full Text PDF