Continuous Disentangled Joint Space Learning for Domain Generalization.

Domain generalization (DG) aims to learn a model on one or multiple observed source domains that can generalize to unseen target test domains. Previous approaches have focused on extracting domain-invariant information from multiple source domains, but domain-specific information is also closely tied to semantics in individual domains and is not well-suited for generalization to the target domain. In this article, we propose a novel DG method called continuous disentangled joint space learning (CJSL), which leverages both domain-invariant and domain-specific information for more effective DG.

Geometric Correspondence-Based Multimodal Learning for Ophthalmic Image Analysis.

Color fundus photography (CFP) and Optical coherence tomography (OCT) images are two of the most widely used modalities in the clinical diagnosis and management of retinal diseases. Despite the widespread use of multimodal imaging in clinical practice, few methods for automated diagnosis of eye diseases utilize correlated and complementary information from multiple modalities effectively. This paper explores how to leverage the information from CFP and OCT images to improve the automated diagnosis of retinal diseases.

Consistent representation via contrastive learning for skin lesion diagnosis.

Background: Skin lesions are a prevalent ailment, with melanoma emerging as a particularly perilous variant. Encouragingly, artificial intelligence displays promising potential in early detection, yet its integration within clinical contexts, particularly involving multi-modal data, presents challenges. While multi-modal approaches enhance diagnostic efficacy, the influence of modal bias is often disregarded.

Deep Neural Network Augments Performance of Junior Residents in Diagnosing COVID-19 Pneumonia on Chest Radiographs.

Chest X-rays (CXRs) are essential in the preliminary radiographic assessment of patients affected by COVID-19. Junior residents, as the first point-of-contact in the diagnostic process, are expected to interpret these CXRs accurately. We aimed to assess the effectiveness of a deep neural network in distinguishing COVID-19 from other types of pneumonia, and to determine its potential contribution to improving the diagnostic precision of less experienced residents.

Contrastive domain adaptation with consistency match for automated pneumonia diagnosis.

Pneumonia can be difficult to diagnose since its symptoms are too variable, and the radiographic signs are often very similar to those seen in other illnesses such as a cold or influenza. Deep neural networks have shown promising performance in automated pneumonia diagnosis using chest X-ray radiography, allowing mass screening and early intervention to reduce the severe cases and death toll. However, they usually require many well-labelled chest X-ray images for training to achieve high diagnostic accuracy.

A Feature Space-Restricted Attention Attack on Medical Deep Learning Systems.

Deep neural network has shown a powerful performance in the medical image analysis of a variety of diseases. However, a number of studies over the past few years have demonstrated that these deep learning systems can be vulnerable to well-designed adversarial attacks, with minor disruptions added to the input. Since both the public and academia have focused on deep learning in the health information economy, these adversarial attacks would prove more important and raise security concerns.

Adversarial multimodal fusion with attention mechanism for skin lesion classification using clinical and dermoscopic images.

Accurate skin lesion diagnosis requires a great effort from experts to identify the characteristics from clinical and dermoscopic images. Deep multimodal learning-based methods can reduce intra- and inter-reader variability and improve diagnostic accuracy compared to the single modality-based methods. This study develops a novel method, named adversarial multimodal fusion with attention mechanism (AMFAM), to perform multimodal skin lesion classification.

Diagnostic Performance of a Deep Learning Model Deployed at a National COVID-19 Screening Facility for Detection of Pneumonia on Frontal Chest Radiographs.

(1) Background: Chest radiographs are the mainstay of initial radiological investigation in this COVID-19 pandemic. A reliable and readily deployable artificial intelligence (AI) algorithm that detects pneumonia in COVID-19 suspects can be useful for screening or triage in a hospital setting. This study has a few objectives: first, to develop a model that accurately detects pneumonia in COVID-19 suspects; second, to assess its performance in a real-world clinical setting; and third, by integrating the model with the daily clinical workflow, to measure its impact on report turn-around time.

WDCCNet: Weighted Double-Classifier Constraint Neural Network for Mammographic Image Classification.

The early detection and timely treatment of breast cancer can save lives. Mammography is one of the most efficient approaches to screening early breast cancer. An automatic mammographic image classification method could improve the work efficiency of radiologists.

Deep Supervised Domain Adaptation for Pneumonia Diagnosis From Chest X-Ray Images.

Pneumonia is one of the most common treatable causes of death, and early diagnosis allows for early intervention. Automated diagnosis of pneumonia can therefore improve outcomes. However, it is challenging to develop high-performance deep learning models due to the lack of well-annotated data for training.

Deep adversarial domain adaptation for breast cancer screening from mammograms.

The early detection of breast cancer greatly increases the chances that the right decision for a successful treatment plan will be made. Deep learning approaches are used in breast cancer screening and have achieved promising results when a large-scale labeled dataset is available for training. However, they may suffer from a dramatic decrease in performance when annotated data are limited.

A Dual Simple Recurrent Network Model for Chunking and Abstract Processes in Sequence Learning.

Although many studies have provided evidence that abstract knowledge can be acquired in artificial grammar learning, it remains unclear how abstract knowledge can be attained in sequence learning. To address this issue, we proposed a dual simple recurrent network (DSRN) model that includes a surface SRN encoding and predicting the surface properties of stimuli and an abstract SRN encoding and predicting the abstract properties of stimuli. The results of Simulations 1 and 2 showed that the DSRN model can account for learning effects in the serial reaction time (SRT) task under different conditions, and the manipulation of the contribution weight of each SRN accounted for the contribution of conscious and unconscious processes in inclusion and exclusion tests in previous studies.

Feature-Sensitive Deep Convolutional Neural Network for Multi-Instance Breast Cancer Detection.

To obtain a well-performed computer-aided detection model for detecting breast cancer, it is usually needed to design an effective and efficient algorithm and a well-labeled dataset to train it. In this paper, first, a multi-instance mammography clinic dataset was constructed. Each case in the dataset includes a different number of instances captured from different views, it is labeled according to the pathological report, and all the instances of one case share one label.

Deep Manifold Preserving Autoencoder for Classifying Breast Cancer Histopathological Images.

Classifying breast cancer histopathological images automatically is an important task in computer assisted pathology analysis. However, extracting informative and non-redundant features for histopathological image classification is challenging due to the appearance variability caused by the heterogeneity of the disease, the tissue preparation, and staining processes. In this paper, we propose a new feature extractor, called deep manifold preserving autoencoder, to learn discriminative features from unlabeled data.

Breast cancer cell nuclei classification in histopathology images using deep neural networks.

Purpose: Cell nuclei classification in breast cancer histopathology images plays an important role in effective diagnose since breast cancer can often be characterized by its expression in cell nuclei. However, due to the small and variant sizes of cell nuclei, and heavy noise in histopathology images, traditional machine learning methods cannot achieve desirable recognition accuracy. To address this challenge, this paper aims to present a novel deep neural network which performs representation learning and cell nuclei recognition in an end-to-end manner.