Ultrasound-assisted enzymatic extraction of hydroxy-sanshool compounds from the hydrodistillation residue of two Sichuan peppers: optimization, quantification and pungent taste contribution evaluation.

Hydroxy-sanshool compounds were extracted from the hydrodistillation residue of Maxim. pericarp (ZBM) and DC. pericarp (ZADC) by using ethanol-water extraction and extractions assisted with (i) enzymes, (ii) ultrasound, and (iii) enzymes and ultrasound.

A multiplex loop-mediated isothermal amplification assay for rapid detection of Bacillus cereus and Staphylococcus aureus.

Bacillus cereus (B. cereus) and Staphylococcus aureus (S. aureus) are major human food-borne pathogens that may produce a variety of toxins and cause diarrhea, food poisoning, and even death.

Enhanced osteoinductivity of porous biphasic calcium phosphate ceramic beads with high content of strontium-incorporated calcium-deficient hydroxyapatite.

Further biomimicking natural bone and enhancing osteoinductivity to meet the requirements of regenerative medicine is the key development direction of biphasic calcium phosphate (BCP) ceramics. Bone mineral is a kind of Ca-deficient hydroxyapatite (CDHA) with many kinds of trace ions incorporated; however, little is actually known regarding the incorporation of trace ions in CDHA, and trace-ions-incorporated CDHA in BCP ceramics has seldom been studied. The present study introduces an effective approach to fabricate porous BCP ceramic beads with a high content of strontium (Sr)-incorporated CDHA (BCP-Sr), and investigated its biological performance, especially with regard to osteoinductivity.

Stabilization of Ca-deficient hydroxyapatite in biphasic calcium phosphate ceramics by adding alginate to enhance their biological performances.

It is of significance to further improve the bioactivity of existing calcium phosphate (Ca-P) biomaterials to satisfy the needs of regenerative medicine. Due to its compositional similarity to natural bone mineral, calcium-deficient hydroxyapatite (CDHA) is supposed to possess excellent bioactivity. However, it is difficult to fabricate Ca-P ceramics with a high amount of CDHA, as CDHA is easy to decompose during the sintering process.

Fabrication and Properties of Ca-P Bioceramic Spherical Granules with Interconnected Porous Structure.

Spherical calcium phosphate (Ca-P) granules show advantages in filling bone cavity defects. In this study, gelatinizing technology combined with microsphere-sintering and gas-foaming methods was applied to fabricate porous spherical Ca-P bioceramic granules. The obtained three kinds of Ca-P granules (i.