Publications by authors named "Yanggang Ouyang"
Background: The treatment of unstable scaphoid fracture and nonunion remains a challenging problem for hand surgeons. Minimally invasive treatment has become the preferred method of treatment.
Purpose: This study introduces the arthroscopic technique with two headless compression screws (HCS) fixation and distal radius bone grafting for the treatment of unstable scaphoid fracture and nonunion, aiming to evaluate its clinical and radiological outcomes.
TP53 protein is lost or mutated in about half of all types of human cancers and small molecules to regulate mutant p53 repair, or interrupt ubiquitination degradation of p53 induced by E3-ubiquitin ligase Mdm2 have a potential application in clinical application. To inhibit the deubiquitinase activity of 19S proteasome and restore the p53 protein level, in this study, we utilized p53 knockout mice to test the anti-cancer effect of a specific USP14 and UCH37 inhibitor b-AP15. Our results show that UCHL5, USP14 and COPS5 are upregulated in p53-related tumors, and higher expression of these genes results in a shorter overall survival in patients with p53 deficiency.
View Article and Find Full Text PDF[Effectiveness analysis of maintaining the stability between the fourth and the fifth metacarple base during the treatment in the hamate-metacarpal joint injury].
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
August 2018
Article Synopsis
- The study aimed to assess how maintaining stability between the fourth and fifth metacarpal bases impacts treatment outcomes for hamate-metacarpal joint injuries.
- Between September 2015 and June 2017, 13 patients (12 males, 1 female) with varying levels of metacarpal injuries were treated, with most injuries stemming from heavy boxing and falls.
- Post-operative results showed no complications, with all fractures healing properly within an average of 6.3 weeks and hand function largely rated as excellent or good after a 6-month recovery period.