Publications by authors named "Yangfa Zeng"

To investigate the pattern and threshold of physiological growth, defining as axial length (AL) elongation that results in little refraction progression, among Chinese children and teenagers, a total of 916 children aged between 7 and 18 years from a 6-year longitudinal cohort study were included for analysis. Ocular biometry, cycloplegic refraction and demographic data were obtained annually. Physiological growth was calculated based on myopic progression and Gullstrand eye model, respectively.

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Article Synopsis
  • The study looked at how effective and safe laughter exercises are for people suffering from dry eye disease.
  • It was conducted at a big eye clinic in China with participants aged 18-45 who had symptoms of dry eyes.
  • Participants were divided into two groups: one did laughter exercises while the other used regular eye drops, and they were monitored for changes in their symptoms over eight weeks.
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Aims: To document longitudinal changes in spherical equivalent refraction (SER) and related biometric factors during early refractive development.

Methods: This was a prospective cohort study of Chinese children, starting in 2018 with annual follow-ups. At each visit, children received cycloplegic autorefraction and ocular biometry measurements.

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Background: Myopia is a leading cause of visual impairment in Asia and worldwide. However, accurately predicting the progression of myopia and the high risk of myopia remains a challenge. This study aims to develop a predictive model for the development of myopia.

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Article Synopsis
  • - The study aimed to observe changes in subfoveal choroidal thickness (SFCT) in children aged 3 to 14 in Guangzhou, China, over two years, categorizing them into groups based on their refractive status: persistent non-myopia, persistent myopia, and newly developed myopia.
  • - Findings showed that SFCT decreased significantly in newly myopic children while showing variability in thickness among persistent non-myopic and myopic groups, with specific patterns of thickening and thinning depending on their refractive progression or stability.
  • - Ultimately, the research concluded that SFCT increased in stable, non-myopic children and remained stable in myopic children with stable refraction, while it decreased in children with
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Purpose: To evaluate the association of body stature with ocular biometrics and refraction in preschool children.

Methods: A cross-sectional, school-based study was conducted in Shenzhen, China. Preschool children aged 3 to 6 from 10 randomly-selected kindergartens were recruited.

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Purpose: Long-term axial length (AL) shortening in myopia is uncommon but noteworthy. Current understanding on the condition is limited due to difficulties in case collection. The study reported percentage, probability, and time course of long-term AL shortening in myopic orthokeratology based on a large database.

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Importance: The beneficial effects of increasing outdoor physical activity time on children's myopia onset and physical well-being are widely acknowledged. However, in countries with competitive educational systems, such as China, parents and school administrators may be relatively reluctant to increase the extracurricular physical activity time for children due to concerns that this action will compromise children's academic performance.

Objective: To investigate whether additional extracurricular physical activity time after school compromises the academic performance of schoolchildren.

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Purpose: Visual impairment from cataracts is closely associated with low income, but trial evidence regarding the impact of surgery on income is lacking. We investigated whether cataract surgery could increase personal income.

Design: A 2-arm, parallel-group, open-label, randomized controlled trial (ClinicalTrials.

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Purpose: To assess the longitudinal changes in crystalline lens in persistent non-myopic and myopic children.

Methods: Four cohorts of children were recruited from Guangzhou, China, from first year of kindergarten (G0, n = 1129), first year of primary school (G1, n = 1324), fourth year of primary school (G4, n = 1854), and first year of junior high school (G7, n = 867) in 2018 and followed up annually for 2 years. All children received cycloplegic autorefraction and ocular biometry measurement.

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Background: The physical process of axial length growth among children and its role in the occurrence of myopia remain insufficiently explored. In this study, we investigate the patterns of ocular axial growth among persistent myopia (PM) and persistent non-myopia (PNM) children aged 3 to 15 years. Methods: A group of 6353 children aged 3 to 15 years, selected from rural schools in China, were followed up annually for 2 years.

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Introduction: Myopia is the common cause of reduced uncorrected visual acuity among school-age children. It is more prevalent in urban than in rural areas. Although many myopia studies have focused on the effect of urbanisation, it remains unclear how visual experience in urban regions could affect childhood myopia.

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Objectives: To investigate the prevalence of and risk factors for Demodex mite infestation of the eyelashes in Chinese children.

Methods: A total of 1,575 children were surveyed from June 2017 to January 2019 and stratified into two age groups: 3 to 6 and 7 to 14 years. All subjects underwent routine eye examination and lash epilation for Demodex mite identification and counting using microscopy.

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Background: We investigated whether specific appointments for quality-assured care could increase referral uptake, often low in China, in children's vision screening.

Methods: We randomized children aged 4-7 years in Yudu, Jiangxi, China, by school to Control (free school-based eye screening, parents of children failing screening recommended for further examination [usual practice]) or Intervention (identical examinations, with parents additionally provided with specific appointments for further examinations by quality-assured doctors at a designated local hospital). Both groups could select any hospital for referral exams, which were not free.

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Purpose: To document the distribution of ocular biometry and to evaluate its associations with refraction in a group of Chinese preschoolers.

Design: Population-based cross-sectional study.

Participants: A total of 1133 preschoolers 3 to 6 years of age from 8 representative kindergartens.

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Purpose: To compare the education effect of video demonstrations and conventional teaching on the prevention and control of myopia.

Methods: Eighty students were randomly divided into an experimental (n = 40) and a control (n = 40) group, and each group was split into two classes of 40 students. The students in the experimental group attended classes mainly based on video demonstration and those in the control group received conventional teaching.

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Importance: Myopia has reached epidemic levels in parts of East and Southeast Asia. However, there is no effective intervention to prevent the development of myopia.

Objective: To assess the efficacy of increasing time spent outdoors at school in preventing incident myopia.

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Purpose: To document the distribution of uncorrected visual acuity (UCVA) in a defined population of Chinese preschoolers and to discuss its implications for vision referral.

Methods: Preschoolers aged 3 to 6 years old were recruited from kindergartens in Shenzen. Uncorrected visual acuity was estimated by using Early Treatment Diabetic Retinopathy Study Tumbling E charts, followed by cycloplegic refraction and ocular examination.

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Importance: This article provides, to our knowledge, the first longitudinal population-based data on refractive error (RE) in Chinese persons.

Objective: To study cohort effects and changes associated with aging in REs among Chinese adults.

Design, Setting, And Participants: A 2-year, longitudinal population-based cohort study was conducted in southern China.

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Purpose: To compare the repeatability and consistency of anterior segment optical coherence tomography (AS-OCT) and ultrasound biomicroscopy (UBM) in measuring iris parameters in patients with primary angle closure glaucoma.

Methods: Twenty-two patients (38 eyes) with primary angle closure glaucoma, including 5 eyes with acute angle closure glaucoma, 10 fellow eyes of acute angle closure glaucoma, and 23 eyes with chronic angle closure glaucoma, were recruited consecutively in our hospital. All subjects underwent anterior scanning by AS-OCT and UBM.

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Purpose: To investigate gender differences in lens thickness (LT) and central anterior chamber depth (ACD) in normal subjects, and to assess age associated changes in these measures.

Methods: The anterior chamber depth (ACD), and lens thickness (LT), of 150 normal subjects (150 eyes) was measured by anterior segment optical coherence tomography (AS- OCT). Gender differences were assessed by independent t-test, and correlation analysis was used to examine the effect of age.

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Objective: To study the population distribution and longitudinal changes in anterior chamber angle width and its determinants among Chinese adults.

Design: Prospective cohort, population-based study.

Participants: Persons aged 35 years or more residing in Guangzhou, China, who had not previously undergone incisional or laser eye surgery.

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Article Synopsis
  • - This study investigates how surgical peripheral iridectomy (SPI) affects the anterior segment configuration in patients with primary acute angle closure glaucoma (PAACG) using anterior segment optical coherence tomography (AS-OCT).
  • - Researchers analyzed data from 37 eyes, measuring several factors like anterior chamber depth and angle opening before and after SPI, finding significant increases in most parameters except for anterior chamber depth and crystalline lens rise.
  • - The results indicate that SPI effectively helps manage PAACG, leading to improved measurements of angle and chamber volume, but does not significantly change anterior chamber depth or crystalline lens position.
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Objective: To compare visual and refractive outcomes between self-refracting spectacles (Adaptive Eyecare, Ltd, Oxford, UK), noncycloplegic autorefraction, and cycloplegic subjective refraction.

Design: Cross-sectional study.

Participants: Chinese school-children aged 12 to 17 years.

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Objective: To examine factors influencing adherence to spectacle wear and perceived value within a prospective 1-month trial of ready-made and custom spectacles in school-aged children with uncorrected refractive error in urban China.

Methods: A total of 428 students aged 12 to 15 years with at least 1 diopter of uncorrected refractive error were given free spectacles and evaluated 1 month later at an unannounced visit. Demographic factors, vision, optical effects, and perceptions were modeled as predictors of observed use and perceived value using logistic regression adjusted for spectacle allocation.

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