Publications by authors named "Yangchen Wang"
Article Synopsis
- This study investigates the effects of Panax notoginseng saponins (PNS) on diabetic kidney disease (DKD) using network pharmacology, molecular docking, and animal experiments.
- Key targets identified for PNS include AKT1, STAT3, and others, with relevant pathways related to cancer and signaling highlighted in the analysis.
- Animal trials showed that PNS significantly lowered blood glucose levels and improved kidney damage in diabetic mice, indicating its potential therapeutic effect on DKD.
We present an intelligent photothermal therapy agents by functionalizing gold nanoparticles with specific nucleic acid sequences. Hairpin nucleic acids are modified to the nanoparticles, forming AuNPs-1 and AuNPs-2. Upon infiltrating cancer cells, these nanoparticles undergo catalytic hairpin assembly in the presence of target miRNA, leading to aggregation and subsequent photothermal conversion.
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