[The relationship between percentage body fat, waist-hip ratio and cardiovascular function in the adult females of Heilongjiang province].

Objective: To analyze the relationship between body fat mass and distribution and cardiovascular function in the adult females of Heilongjiang province.

Methods: Based on the statistic variable random sampling principal, we selected 1903 healthy adult females with ages of 18 - 70 years old in Heilongjiang province to conduct the study. The height, body weight, waist, chest measurement and waist-hip ratio (WHR) were measured.

[Comparison of the systemic vascular resistance and the correlative factors in Han and Korean populations of China.].

In the present study, the differences in systemic vascular resistance (SVR) and the correlated risk factors between Han and Korean residents were investigated. 1 647 Hans and 876 Koreans from Mudanjiang and Hailin areas of Heilongjiang Province were examined with BIOZ Cardio Dynamics Monitor. A series of factors were determined, including SVR, systemic vascular resistance index (SVRI), systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), cardiac output (CO), cardiac output index (CI) and heart rate (HR).

[Study on expression of PS1 in APP-PS1 double gene stably transfected cell lines and its relation to gamma-secretase].

Objective: To study the role of presenilin1 (PS1) in the processing of beta-amyloid precursor protein (APP) to amyloid beta-peptide (Abeta) and its relation to gamma-secretase in the pathogenesis of Alzheimer's disease (AD).

Methods: Several CHO cell lines stably transfected with either wide-type or mutant PS1 (M(146)L) along with APP(751) genes were established. The expression of PS1 and its half-life were determined by immunoprecipitation, Western blotting and pulse-chase experiment.