Chemical characterization of a PD-1/PD-L1 inhibitory activity fraction of the ethanol extract from .

Searching for PD-1/PD-L1 inhibitor from medicinal plants has become a potential method to discover small molecular cancer immunotherapy drugs. Using PD-1/PD-L1 inhibitory activity assay , a bioactive fraction was obtained from the ethanol extract of . A sensitive UPLC-HRMS/MS method was established for the rapid screening and identification of compositions from bioactive fraction.