Levamisole Ameliorates Rheumatoid Arthritis by Downregulating the PI3K/Akt Pathway in SD Rats.

Rheumatoid arthritis (RA) is a systemic chronic autoimmune disease characterized by a protracted course, high rates of morbidity, and disability yet lacks effective therapeutic modalities. Levamisole (LVM), an immunomodulatory drug, has been clinically reported for its potential in RA treatment, while its therapeutic mechanism toward RA remains to be elucidated. Hence, this study provides theoretical support for the application of LVM in the treatment of RA.

An acute gastric volvulus in a child with congenital left diaphragmatic hernia: a case report.

Background: Acute complete gastric volvulus is a rare and life-threatening disease, which is prone to gastric wall ischemia, perforation, and necrosis. If it is not treated by surgery in time, the mortality rate can range from 30 to 50%. Clinical presentations of acute gastric volvulus are atypical and often mimic other abdominal conditions such as gastritis, gastroesophageal reflux, gastric dilation, and pancreatitis.

"Our City Will Be the First to Hold Both Summer and Winter Olympics": A comparative analysis of how media coverage and public opinion were framed on social media in the lead up to the Beijing 2022 winter Olympic games.

Introduction: Beijing is the first city to host both the Summer and Winter Olympic Games. Mega sporting events such as the Olympic Games, which attract mass audiences, benefit greatly from social media. This article examines how the news coverage and public opinion about the Beijing 2022 were articulated on social media in the lead up to the Beijing 2022.

Near-Infrared Trapping by Surface Plasmons in Randomized Platinum-Ceramic Metamaterial for Thermal Barrier Coatings.

As the operation temperature of next generation gas turbine is targeted to be 1800 °C toward a higher efficiency and lower carbon emission, the near-infrared (NIR) thermal radiation becomes a major concern for the durability of the metallic turbine blades. Although thermal barrier coatings (TBCs) are applied to provide thermal insulations, they are translucent to the NIR radiation. It is a major challenge for TBCs to achieve optically thick with limited physical thickness (usually < 1 mm) for effectively shielding the NIR radiation damage.

Customer agility, market orientation, and brand image in the context of Chinese market.

Introduction: Customer agility (CA) and market orientation have been widely discussed in prior research. Also, the role of brand image in business making-decision has been emphasized. However, the current analysis lacks integrating the relationship among the three concepts.

Ultra-dense dislocations stabilized in high entropy oxide ceramics.

Dislocations are commonly present and important in metals but their effects have not been fully recognized in oxide ceramics. The large strain energy raised by the rigid ionic/covalent bonding in oxide ceramics leads to dislocations with low density (∼10 mm), thermodynamic instability and spatial inhomogeneity. In this paper, we report ultrahigh density (∼10 mm) of edge dislocations that are uniformly distributed in oxide ceramics with large compositional complexity.

The Kinetics of Aging and Reducing Processes of Cr(VI) in Two Soils.

To investigate the aging process and reduction of Cr(VI) in two soils. The adsorption behavior of the soils demonstrated that the paddy soil had higher adsorption capacity for Cr(VI), but the capacity was lower for Cr(III), which contrasted the results for fluro-aquic soil. The mobilizable Cr was assessed using EDTA extraction.