Risk prediction and early intervention strategies for persistent SARS-CoV-2 infection in patients with non-Hodgkin lymphoma: a retrospective cohort study.

Background: Patients with non-Hodgkin lymphoma (NHL) face heightened mortality and accelerated disease progression when persistently infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This critical situation underscores the urgent need to identify risk factors and establish early intervention strategies tailored to this vulnerable population. The primary aim of this study was to investigate the risk factors associated with persistent SARS-CoV-2 infection in NHL patients during the COVID-19 pandemic.

Arthroscopic Upper Third Subscapularis Tendon Repair Using H-Loop Technique: A Case Series.

Objective: Arthroscopic repair of upper one-third subscapularis tendon tears remains challenging due to suture management difficulties and repair quality limitations. We proposed a simpler knotless technique-the H-Loop technique. This study evaluates its early clinical and imaging outcomes.

Phenylpropanoids of Eleutherococcus senticosus (Rupr. & maxim.) maxim. Alleviate oxidative stress in Alzheimer's disease in vitro and in vivo models by regulating Mst1 and affecting the Nrf2/Sirt3 pathway.

Alzheimer's disease (AD) is a common neurodegenerative disorder, and oxidative stress plays a significant role in its progression. Owing to its nourishing effects, Eleutherococcus senticosus (Rupr. & maxim.

Exploring the influence of individual digitalization on technostress in Chinese IT remote workers: The mediating role of Information Processing demands and the Job Complexity.

This research study explores the connection between individual digitalization and technostress among Chinese IT remote workers, focusing on the mediating roles of Information Processing volume and Job Complexity. Concurrently, the escalation in both the volume of Information Processing and the Job Complexity necessitates higher levels of individual digitalization, potentially influencing technostress. The study specifically examines how the digitalization levels of remote workers relate to their work-related stress, as well as the potential mediating role of Information Processing demands, encompassing Job Complexity and the quantity of Information Processing.

Size-dependent interactions between calciprotein particles and vascular endothelium.

The underlying mechanisms governing the interactions between nanoparticles and vascular endothelial barrier remain largely unexplored, which is crucial for the optimal design of nanoparticles for clinical applications. In this study, the size-dependent interactions between calciprotein particles (CPPs) and endothelial cells (ECs) were investigated using a rat model of chronic kidney disease (CKD) induced by 5/6 nephrectomy. Two primary types of CPP1 were studied: small-sized CPP1 (S-CPP1, <50 nm) and larger CPP1 (L-CPP1, <100 nm), detected three and five weeks post-surgery, respectively.

Postoperative pneumonia in isolated coronary artery bypass grafting: A comprehensive study of epidemiology, etiology, and disease burden from China (2020-2023).

Objective: To investigate the epidemiological trends,etiological profiles and disease burden metrics related to postoperative pneumonia following isolated coronary artery bypass grafting (CABG).

Methods: A retrospective analysis was conducted on data from 518 patients who developed postoperative pneumonia following isolated CABG between January 1, 2020, and November 30, 2023.

Results: Postoperative pneumonia occurred at a rate of 11.

Focus-Driven Augmented Feedback: Enhancing Focus and Maintaining Engagement in Upper Limb Virtual Reality Rehabilitation.

Integrating biofeedback technology, such as real-time eye-tracking, has revolutionized the landscape of virtual reality (VR) rehabilitation games, offering new opportunities for personalized therapy. Motivated to increase patient focus during rehabilitation, the Focus-Driven Augmented Feedback (FDAF) system was developed to enhance focus and maintain engagement during upper limb VR rehabilitation. This novel approach dynamically adjusts augmented visual feedback based on a patient's gaze, creating a personalised rehabilitation experience tailored to individual needs.

Effects of empathy on the perspectives of respectful and disrespectful maternity care among nursing and midwifery students in China: A cross-sectional study.

Background: Empathy is a crucial attribute in healthcare, benefiting both professionals and patients. It also plays an important role in the midwife-woman relationship, contributing to the implementation of respectful maternity care. Witnessing acts of disrespect towards childbearing women in the clinical setting may impair students' perceptions of respectful maternity care, as they may come to view disrespect as normative.

HNRNPC promotes progression of non-small cell lung cancer by maintaining TFAP2A mRNA stability.

Background: HNRNPC is an RNA-binding protein that is overexpressed in a variety of cancers and is well known as an m6A "reader", but its specific function and molecular mechanism in NSCLC have not been fully understood. This study aimed to discuss molecular mechanism of HNRNPC in NSCLC.

Methods: HNRNPC expression and clinically relevant data in pan-cancer and LUAD were extracted through these websites, including UALCAN, TIMER2 and GEPIA.

Highly Stereoselective 1,2-cis-Xylosylation Enabled by Reagent Modulation, Remote Participation, and Electron-Withdrawing Synergistic Effects.

Stereoselective constructions of 1,2-cis-glycosidic bonds are long-standing challenges in chemical synthesis. In particular, achieving highly stereoselective 1,2-cis-xylosylation remains a difficult task in carbohydrates chemistry. Here, we report that highly stereoselective 1,2-cis-xylosylation could be achieved via synergistic combinations of reagent modulation, remote participation, and electron-withdrawing effects.

New 14,15-dinor--clerodane and -clerodane diterpenoids from Wall. ex benth.

One new diterpenoid possessing a rare 14,15-dinor--clerodane framework, ajugamacrin H (), and one new -clerodane diterpenoid, ajugamacrin I (), along with seven known analogues (-), were obtained from Wall. ex Benth..

Successful pregnancy following cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in patients with peritoneal malignancies.

Background: Cytoreductive surgery (CRS) with Hyperthermic Intra-peritoneal Chemotherapy (HIPEC) has become a successful, potentially curative, treatment option for peritoneal surface malignancies (PSM). CRS and HIPEC (CRS/HIPEC) are performed with curative intent for several intra-peritoneal pathologies. An increasing number of patients with PSM are diagnosed at a relatively young age.

The Naples prognostic score as a new predictive index of severe abdominal aortic calcification: a population-based study.

Purpose: Abdominal aortic calcification (AAC) is related to inflammation and nutritional status. The Naples prognostic score (NPS) is an innovative biological marker capable of reflecting systemic inflammation and nutritional status. This research seeks to investigate the correlation of NPS with severe abdominal aortic calcification (SAAC).

Interaction of glycosylated legumin with EGCG and quercetin: structure and stability analysis.

Background: Polyphenols have a strong binding capacity with proteins, but the binding behavior of polyphenols with glycosylated proteins and the effects of binding on the structure of glycosylated proteins have been less studied.

Results: This study used enzymatic modification to prepare an oligochitosan-legumin complex (OLC) to investigate its interaction with (-)-epigallocatechin gallate (EGCG) and quercetin. Fluorescence spectroscopy experiments showed that the binding site of OLC to EGCG was 27.

Energy Metabolism Supports Molecular and Functional Heterogeneity of Reactive Astrocytes in Central Nervous System Disorders.

Astrocytes undergo a reactive transformation in central nervous system (CNS) disorders, manifesting significant heterogeneity in morphology, molecules, function, and spatial distribution. Just like all cells, astrocytes necessitate energy for their basic functions. Energy production proves critical for the survival and development of astrocytes, as well as their fate determination and functional diversity.

The combined effect between environmental exposure and oxidative stress-related susceptible gene polymorphisms on human semen quality.

Purpose: The aim of the current study was to investigate the relationship between environmental factors and metabolic gene genotypes related to semen quality.

Methods: A total of 341 men were recruited and classified into normal or abnormal semen quality groups according to the World Health Organization's 2010 criteria. Alcohol and tobacco use among men was self-reported.

A Human-Prosthesis Coupled Musculoskeletal Model for Transtibial Amputees.

In this paper, we present a human-prosthesis coupled full-body musculoskeletal model that integrates the dynamics of the muscle-driven human body and a motor-driven robotic prosthesis. This model can be used to perform the inverse kinematics and dynamics calculation based on measurements for amputees wearing a force-controlled or position-controlled prosthesis. As a result, we can analyze the impacts of prostheses on amputee kinetic states, such as joint torques and muscle forces.

Long-Term Feature Extraction via Frequency Prediction for Efficient Reinforcement Learning.

Sample efficiency remains a key challenge for the deployment of deep reinforcement learning (RL) in real-world scenarios. A common approach is to learn efficient representations through future prediction tasks, facilitating the agent to make farsighted decisions that benefit its long-term performance. Existing methods extract predictive features by predicting multi-step future state signals.

MixSA: Training-free Reference-based Sketch Extraction via Mixture-of-Self-Attention.

Current sketch extraction methods either require extensive training or fail to capture a wide range of artistic styles, limiting their practical applicability and versatility. We introduce Mixture-of-Self-Attention (MixSA), a training-free sketch extraction method that leverages strong diffusion priors for enhanced sketch perception. At its core, MixSA employs a mixture-of-self-attention technique, which manipulates self-attention layers by substituting the keys and values with those from reference sketches.

Portable analytical system integrating purge and trap and microplasma optical emission spectrometry for online discriminative detection of NO.

Pollution caused by nitrogen oxides (NO, mainly NO and NO) has attracted considerable attention due to its negative implications on the environment and human health. Herein, a novel, portable, and battery-operated system integrating a purge and trap (P&T) system with a miniaturized point discharge optical emission spectrometer (μPD-OES) was developed for monitoring atmospheric NO. Among NO, NO can be selectively and directly absorbed by sodium hydroxide (NaOH) solution and converted to nitrite (NO).

Risk Factors and An Interpretability Tool of In-hospital Mortality in Critically Ill Patients with Acute Myocardial Infarction.

Purpose: We aim to develop and validate an interpretable machine-learning model that can provide critical information for the clinical treatment of critically ill patients with acute myocardial infarction (AMI).

Methods: All data was extracted from the multi-centre database (training and internal validation cohorts: MIMIC-III/-IV, external validation cohort: eICU). After comparing different machine-learning models and several unbalanced data processing methods, the model with the best performance was selected.

Hotspots and Trends in Spinal Cord Stimulation Research for Spinal Cord Injury: A Bibliometric Analysis with Emphasis on Motor Function Recovery (2014-2024).

Background: Spinal cord stimulation (SCS) has emerged as a key therapeutic strategy for enhancing motor recovery in spinal cord injury (SCI). This study employs bibliometric analysis to explore research trends and hotspots in SCS for motor recovery, highlighting advances and emerging directions over the past decade.

Methods: This cross-sectional bibliometric study retrieved publications on SCS for motor recovery from the Web of Science Core Collection database (2014-2024).

Three-branch feature enhancement and fusion network for focal cortical dysplasia lesions segmentation using multimodal imaging.

Objective: Conventional multimodal imaging, including MRI and fluorodeoxyglucose positron emission tomography (FDG-PET), has difficulty in accurately detecting subtle or blurred focal cortical dysplasia (FCD) lesions. Morphometric maps assist localization by highlighting abnormal regions, whereas wavelet-filtered images emphasize texture and edge details. Therefore, we propose a three-branch feature enhancement and fusion network (TBFEF-Net) that integrates conventional multimodal imaging, morphometric maps, and wavelet-filtered images to enhance the accuracy of FCD localization.

Down-regulation of PCK2 enhanced the radioresistance phenotype of nasopharyngeal carcinoma.

Purpose: Radiotherapy is the main treatment for non-distant metastatic nasopharyngeal carcinoma (NPC). However, about 15% of NPC patients still experience local tumor recurrence after radiotherapy. The mechanisms underlying the radioresistance of NPC have not been fully understood.