Background: Frailty and sarcopenia are typical geriatric conditions with a complex pathophysiology. Extracellular vesicles (EVs) are key regulators of age-related diseases, but the mechanisms underlying physical frailty, sarcopenia, and EVs are not well understood.
Methods: A systematic literature review was conducted to examine the evidence supporting an association between EVs and physical frailty and/or sarcopenia by searching the electronic databases, including the Cochrane Library, PubMed, and Embase, from January 2000 to January 2021.
Unlabelled: The purpose of this study was to apply a skin suspension to accelerate wound healing at the skin donor site.
Methods: A small fragment of skin was collected after skin transplantation had been performed. The skin suspension was prepared by mixing the small fragments of skin tissue with the same volume of normal saline.