Research on EV Crawler-Type Soil Sample Robot Using GNSS Information.

In Japan, the decline in the number of agricultural workers and the aging of the workforce are problems, and there is a demand for more efficient and labor-saving work. Furthermore, in order to correct the rising price of fertilizer and the increasing burden on the environment caused by fertilizer, there is a demand for more efficient fertilization. Therefore, we aim to develop an electric soil sampling robot that can run autonomously using Global Navigation Satellite System (GNSS) information.

Photothermal-enhanced silver nanocluster bioactive glass hydrogels for synergistic antimicrobial and promote wound healing.

Antibacterial hydrogels are promising for combating infections and promoting wound healing. Nevertheless, excessive antibiotics induce resistance, and high metal ion levels cause cytotoxicity, complicating healing. Here, we introduce a hydrogel incorporating polydopamine-coated bioactive glass (BGs@PDA) on reduced graphene oxide (rGO) with photothermal therapy (PTT) and silver nanoclusters (AgNCs) for synergistic antibacterial treatment.

Development of a Grape Cut Point Detection System Using Multi-Cameras for a Grape-Harvesting Robot.

Harvesting grapes requires a large amount of manual labor. To reduce the labor force for the harvesting job, in this study, we developed a robot harvester for the vine grapes. In this paper, we proposed an algorithm that using multi-cameras, as well as artificial intelligence (AI) object detection methods, to detect the thin stem and decide the cut point.

Novel decision-level fusion strategies combined with hyperspectral imaging for the detection of soybean protein content.

Soybeans are used for human consumption or animal feed due to their abundant protein content. In this study, visible-near infrared (VNIR) hyperspectral imaging (HSI) and short-wave infrared HSI combined with three-levels data fusion methods were employed to detect the protein content of soybean seeds, including measurement-level fusion, feature-level fusion, and decision-level fusion. Additionally, three novel decision-level fusion methods were proposed, including binary linear regression, feature-based multiple linear regression (MLR), and model-based MLR.

Association between various cathepsins and uterine leiomyoma: A Mendelian randomization analysis.

Emerging evidence suggests a tentative association between cathepsins and uterine leiomyoma (UL). Previous investigations have predominantly focused on the role of cathepsins in the metastasis and colonization of gynecological malignancies. Still, observational studies may lead to confounding and biases.

Underlying Mechanism of Lysosomal Membrane Permeabilization in CNS Injury: A Literature Review.

Lysosomes play a crucial role in various intracellular pathways as their final destination. Various stressors, whether mild or severe, can induce lysosomal membrane permeabilization (LMP), resulting in the release of lysosomal enzymes into the cytoplasm. LMP not only plays a pivotal role in various cellular events but also significantly contributes to programmed cell death (PCD).

Acid Neutralization by Composite Lysine Nanoparticles for Spinal Cord Injury Recovery through Mitigating Mitochondrial Dysfunction.

After spinal cord injury (SCI), significant alterations in the tissue microenvironment lead to mitochondrial dysfunction, inducing apoptosis and inhibiting the remodeling of neural circuits, thereby impeding recovery. Although previous studies have demonstrated a marked decrease in pH at the injury site, creating an acidic microenvironment, the impact of improving this acidic microenvironment on SCI recovery has not been investigated. This study prepared a lysine@hollow mesoporous silica nanoparticle/gelatin methacrylate (GelMA) (L@H/G) composite hydrogel.

Evaluating the pro-survival potential of apoptotic bodies derived from 2D- and 3D- cultured adipose stem cells in ischaemic flaps.

In the realm of large-area trauma flap transplantation, averting ischaemic necrosis emerges as a pivotal concern. Several key mechanisms, including the promotion of angiogenesis, the inhibition of oxidative stress, the suppression of cell death, and the mitigation of inflammation, are crucial for enhancing skin flap survival. Apoptotic bodies (ABs), arising from cell apoptosis, have recently emerged as significant contributors to these functions.

Runx2 Suppresses Astrocyte Activation and Astroglial Scar Formation After Spinal Cord Injury in Mice.

After spinal cord injury, astrocytes undergo a reactive process and form an astroglial scar, which impedes the regeneration of axons. The role of Runx2 in promoting the transformation of astrocytes in the central nervous system is well-established. However, it remains unclear whether Runx2 also plays a role in the development of astroglial scar, and the precise underlying mechanism has yet to be identified.

Exploring the role of parthanatos in CNS injury: Molecular insights and therapeutic approaches.

Background: Central nervous system (CNS) injury causes severe organ damage due to both damage resulting from the injury and subsequent cell death. However, there are currently no effective treatments for countering the irreversible loss of cell function. Parthanatos is a poly (ADP-ribose) polymerase 1 (PARP-1)-dependent form of programmed cell death that is partly responsible for neural cell death.

B(CF)-Catalyzed Formal ( + 3) ( = 5 and 6) Cycloaddition of Bicyclo[1.1.0]butanes to Medium Bicyclo[.1.1]alkanes.

Herein, a B(CF)-catalyzed formal ( + 3) ( = 5 and 6) cycloaddition of bicyclo[1.1.0]butanes (BCBs) with imidazolidines/hexahydropyrimidines is described.

Endoscopic Supracerebellar Infratentorial Transpineal Approach for Posterior-Medial Thalamic Lesions: Surgical Technique and Clinical Experience.

Background And Objectives: Accessing lesions in the posterior-medial thalamus can be challenging because of their deep location and intricate neurovascular anatomy. This study aims to describe the techniques and feasibility of the endoscopic supracerebellar infratentorial transpineal approach for treating posterior-medial thalamus lesions.

Methods: We reviewed and analyzed the clinical outcomes and endoscopic surgical experience of 11 patients with posterior-medial thalamic lesions.

Calculation and program realization of coal pillar setting parameters in Huainan mining area.

Coal pillar retention plays a crucial role in ensuring safety and minimizing ground deformation in coal mining operations. However, accurately and efficiently determining the optimal size of protective pillars, reducing coal pillar pressure, and addressing challenges such as limited access to retention parameters, lengthy observation times, and high labor costs are challenges that must be addressed. In this paper, we presented a methodology using Huainan mine as a case study to address these challenges.

The Status of Wildlife Damage Compensation in China.

The conservation management of natural ecosystems in China has significantly improved in recent decades, resulting in the effective protection of wildlife and the restoration of habitats. With the rapid growth in wildlife populations and corresponding range expansions, incidents of human-wildlife conflict have notably increased across China. However, only a few studies have paid adequate attention to wildlife damage management and compensation.

Catalytic Enantioselective Nucleophilic α-Chlorination of Ketones with NaCl.

Catalytic enantioselective α-chlorination of ketones is a highly desirable process. Different from the conventional approaches that employ corrosive electrophilic chlorination reagents, the process disclosed here employs nucleophilic chloride, aqueous NaCl solution, and even seawater, as green inexpensive chlorine sources. This mechanistically distinct and electronically opposite approach provides facile access to diverse highly enantioenriched acyclic α-chloro ketones that are less straightforward by conventional approaches.

Visual identification of three kinds of human decidual tissues from elective termination of pregnancy.

Introduction: The decidua can be classified into the decidua basalis, decidua capsularis and decidua parietalis. This study aimed to visually identify these three kinds of decidual tissues from fresh samples obtained in early pregnancy based on their macroscopic appearances, which can be discerned visually.

Methods: Decidual samples were collected from 15 pregnant women between 6 and 8 weeks of gestation after elective termination of pregnancy.

Association Between Dysmenorrhea and Risk of Epilepsy in East Asian Populations: A Bidirectional Two-Sample Mendelian Randomization Study.

Dysmenorrhea is associated with epilepsy. Existing evidence is mostly limited to observational studies, which are liable to confounding and bias. This study investigated the causal relevance of dysmenorrhea on epilepsy using Mendelian randomization (MR).

Analysis of Diffusion-Weighted and T2-Weighted Imaging in the Prediction of Distinct Granulation Patterns of Somatotroph Adenomas.

Objective: The heterogeneity of the somatotroph adenomas, especially for sparsely granulated (SG) and densely granulated (DG) subtypes, has attracted great attention in identifying their imaging biomarker. The purpose of the current study was to compare the diagnostic performance of diffusion-weighted and T2-weighted magnetic resonance imaging (MRI) sequences for preoperatively distinguishing the granulation patterns of somatotroph adenomas.

Methods: Thirty-two patients with a clinical diagnosis of somatotroph adenomas from October 2018 to March 2023 were included in this study.

Role of endoscopic third ventriculostomy in patients undergoing resection of pulvinar area lesions: Preliminary clinical results.

Background: Patients with pulvinar area lesions may develop hydrocephalus at any stage. The role of endoscopic third ventriculostomy (ETV) in this setting remains unclear.

Method: We retrospectively enrolled 15 patients with a mean age of 43 years who underwent endoscopic resection of pulvinar area lesions using the supracerebellar infratentorial approach (SCITA).

DADLE promotes motor function recovery by inhibiting cytosolic phospholipase A mediated lysosomal membrane permeabilization after spinal cord injury.

Background And Purpose: Autophagy is a protective factor for controlling neuronal damage, while necroptosis promotes neuroinflammation after spinal cord injury (SCI). DADLE (D-Ala , D-Leu ]-enkephalin) is a selective agonist for delta (δ) opioid receptor and has been identified as a promising drug for neuroprotection. The aim of this study was to investigate the mechanism/s by which DADLE causes locomotor recovery following SCI.

Chemotaxis of Response to Rhizosphere Bacteria.

Rhizosphere microorganisms and the volatile organic compounds (VOCs) produced by them take part in the regulation of the chemotaxis of nematodes. A total of 150 strains of rhizosphere bacteria were screened via a chemotaxis experiment with . Some isolates affected the behavior of the nematodes, including attraction, randomness, and repulsion.