Background: The prevention and treatment of perinatal depression are currently the focus of perinatal health care, with cognitive reactivity confirmed to be an important predictor. However, how cognitive reactivity mediates the relationship between psychosocial factors (e.g.
View Article and Find Full Text PDFBackground: The incidence of cardiovascular diseases among old individuals is on the rise with the growing trend of population aging. Coronary artery bypass grafting (CABG) is an important treatment modality for coronary heart diseases and is increasingly employed in older adults. However, concerns arise due to the poor prognosis following surgery in this population.
View Article and Find Full Text PDFBackground: Obstructive sleep apnea (OSA) is a common sleep-related breathing disorder that is closely associated with metabolic conditions. The Blood Urea Nitrogen to Creatinine Ratio(BUCR) is commonly utilized as a tool for evaluating renal function, particularly in cases where there are concerns about pre-renal or renal causes of azotemia. However, the connection between OSA and BUCR is not yet fully understood.
View Article and Find Full Text PDF4D radar has higher point cloud density and precise vertical resolution than conventional 3D radar, making it promising for adverse scenarios in the environmental perception of autonomous driving. However, 4D radar is more noisy than LiDAR and requires different filtering strategies that affect the point cloud density and noise level. Comparative analyses of different point cloud densities and noise levels are still lacking, mainly because the available datasets use only one type of 4D radar, making it difficult to compare different 4D radars in the same scenario.
View Article and Find Full Text PDFAutologous stem cell transplantation (ASCT) and chimeric antigen receptor T-cells (CAR-T) have been used as consolidation therapies for patients with refractory/relapsed B cell non-Hodgkin's lymphoma (R/R B-NHL) in remission after second-line chemotherapy or salvage therapy. However, patients with different pathological subtypes and remission states may benefit differently from ASCT or CAR-T cell therapy. Furthermore, consolidation treatment involving ASCT or CAR-T cells still poses a significant risk of disease relapse.
View Article and Find Full Text PDFPigs are vital genetic mixing vessels for human and avian influenza viruses because their tracheal epitheliums possess both sialic acid α-2,6-Gal and α-2,3-Gal receptors. Cross-species transmission of influenza A viruses from swine to humans occurs occasionally. The first case of human infection with the Eurasian avian-like H1N1 swine influenza virus (EAH1N1 SIVs) genotype G4 was detected in Jiangsu Province, China, in February 2023, and backtracking epidemiological investigations did not reveal a clear source of the infection.
View Article and Find Full Text PDFWith a prolonged refrigeration time, dough becomes syruped and the gluten strength is weakened, which negatively affects the texture of the dough. At the same time, differences in the growth and metabolism of different yeasts lead to large differences in the physicochemical properties of the dough and the final quality of the product. Therefore, in this study, suitable additives and non- were selected to minimize the effects of long-term refrigeration on the physicochemical properties and microstructure of fermented doughs.
View Article and Find Full Text PDFSuperovulation and embryo transfer are key technologies to improve the reproductive ability of female animals and enhance the efficiency of livestock production. However, poor-quality oocytes or abnormal fluctuations of hormone levels caused by superovulation affect the embryonic development environment, which may lead to a significant decline in the number and quality of transferable embryos, thus reducing the efficiency of superovulation. In this study, nicotinamide adenine dinucleotide (NAD) was injected into Huaxi cows during the superovulation period to observe the proliferation and apoptosis of transplanted embryos.
View Article and Find Full Text PDFHerbal patches are widely used in clinics for their good curative effects. However, due to the complexity of plant matrices and the extremely low content of transdermal components, the individuation of their effective bioactive compounds represents a challenge: there is then a great need for an efficient method to reveal the bioactive ingredients of herbal patches. In this work, a wide-screening approach is proposed to an individuation of transdermal bioactive components in herbal patches obtained by Spatholobus suberectus Dunn (S.
View Article and Find Full Text PDFCarcinoembryonic antigen (CEA) is among the earliest identified tumor markers and remains extensively utilized in the diagnosis and management of colorectal cancer. The detection of CEA presents considerable challenges in the field of analytical chemistry, given its complexity. The most prevalent detection approach is the immunoassay, including the chemiluminescence immunoassay commonly employed in clinical settings; however, discrepancies between various methods persist.
View Article and Find Full Text PDFWhile most recent autonomous driving system focuses on developing perception methods on ego-vehicle sensors, people tend to overlook an alternative approach to leverage intelligent roadside cameras to extend the perception ability beyond the visual range. We discover that the state-of-the-art vision-centric detection methods perform poorly on roadside cameras. This is because these methods mainly focus on recovering the depth regarding the camera center, where the depth difference between the car and the ground quickly shrinks while the distance increases.
View Article and Find Full Text PDFThe development of cost-effective bifunctional electrocatalysts remains a great challenge. In this work, high-performance FeP-CoMoP/NF catalysts were prepared using the strategy of constructing phosphide heterostructures with localized photothermal effect. At 10 mA·cm, the HER overpotential of FeP-CoMoP/NF is 30.
View Article and Find Full Text PDFStreptomyces albidoflavus is a widely used strain for natural product discovery and production through heterologous biosynthetic gene clusters (BGCs). However, the transcriptional regulatory network (TRN) and its impact on secondary metabolism remain poorly understood. Here, we characterize the TRN using independent component analysis on 218 RNA sequencing (RNA-seq) transcriptomes across 88 unique growth conditions.
View Article and Find Full Text PDFBackground: The increasing interest in acupuncture for promoting postoperative rehabilitation has encouraged its use in rehabilitation after total knee arthroplasty (TKA), but its effectiveness remains controversial.
Objective: This study aims to assess the efficacy of different models of acupuncture-related therapies on pain relief, motor function, inflammation, and overall rehabilitation of the knee after TKA.
Methods: Databases PubMed, Embase, Cochrane, Web of Science, Scopus, and Clinicaltrials.
Background: Transmembrane (TMEM) proteins are involved in fundamental biological processes such as material transport and signal transduction. TMEM115 is a member of the TMEM protein family, but its significance in hepatocellular carcinoma (HCC) remains unclear. In this study, we investigate the clinical predictive significance and potential functions of TMEM115 in HCC.
View Article and Find Full Text PDFBackground: TFE3 rearranged renal cell carcinoma (TFE3 rRCC), classified as a distinct entity of RCCs, exhibits aggressive biological behavior and possesses unique metabolic characteristics. In the present study, TFE3 rRCC with high expression of TFE3 fusion proteins was employed to investigate the features of lipid metabolism and its underlying mechanism in cancer progression.
Methods: Fluorescence microscope and flow cytometry were employed to detect lipid droplets (LDs).
Farming activities contribute to soil antibiotic pollution, posing health risks for rural farm workers, especially on small farms in impoverished regions. The effectiveness of large farms in reducing poverty-induced soil antibiotic exposure risk (SABER) remains uncertain. Here we integrate global datasets on concentration of soil antibiotics, rural farm-worker employments and on-farm working hours to quantify SABER.
View Article and Find Full Text PDFA feasible process for the degradation of psyllium arabinoxylan (AX) to arabino-xylo-oligosaccharides (AXOS) is proposed. A suspension of Trichoderma reesei mycelium suspension, acting on seed husks of psyllium as a carbon source, produced endo-β-1,4-xylanase (xynTR) and α-arabinofuranosidase (abfTR), with enzymatic activity levels of 11.09 ± 0.
View Article and Find Full Text PDFThe performance of decorated photocatalysts is highly dependent on the interfacial contact between the cocatalyst and the substrate photocatalyst, which is essentially determined by their fabrication routes. Herein, a simple one-pot preparation method based on low-temperature KSCN flux was developed for the synthesis of sulfide photocatalysts with MS/CdS (MS = CoS, NiS, CuS, SnS, MoS, and WS) as prototypes. The results indicate that a sulfidation of Cd and the cocatalyst precursors can be achieved successively in the reaction system, which facilitates the formation of a welded interface as the cocatalysts can grow epitaxially on the formed CdS surface.
View Article and Find Full Text PDFBackground And Aims: Past studies have shown a substantial overlap between irritable bowel syndrome (IBS) and gastroesophageal reflux disease (GERD). This study investigated the prevalence of DCPR-revised (DCPR-R) syndromes in patients with IBS alone and those with overlapping IBS-GERD. We also explored the relationship of these syndromes with various psychological scales.
View Article and Find Full Text PDFThe overuse of antibiotics in poultry farming has led to the emergence of multidrug-resistant pathogens, posing severe threats to animal health and public safety. Salmonella Pullorum (S. Pullorum), a host-specific pathogen targeting poultry, causes high mortality in chicks and disrupts intestinal health.
View Article and Find Full Text PDFIntroduction: Fruit color is a crucial quality factor strongly influencing consumer preference for citrus. The coloration of citrus fruit is primarily determined by carotenoids, which produce a range of hues. Gibberellic acid (GA) and ethylene are critical in fruit coloration during the ripening process.
View Article and Find Full Text PDFThe dynamic nature of protein conformations is central to their biological functions. Conventional structural biology techniques provide static snapshots, whereas a comprehensive understanding requires an analysis of the dynamic conformations. In this study, we develop a transient cross-linking mass spectrometry method using a photo-cross-linker DCD.
View Article and Find Full Text PDFIEEE Trans Vis Comput Graph
December 2024
Neural implicit fields, such as the neural signed distance field (SDF) of a shape, have emerged as a powerful representation for many applications, e.g., encoding a 3D shape and performing collision detection.
View Article and Find Full Text PDFIEEE Trans Neural Netw Learn Syst
November 2024
Graph representation learning has shown superior performance in numerous real-world applications, such as finance and social networks. Nevertheless, most existing works might make discriminatory predictions due to insufficient attention to fairness in their decision-making processes. This oversight has prompted a growing focus on fair representation learning.
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