Publications by authors named "Yang Kong"

The shuttling of lithium polysulfides (LiPSs), sluggish reaction kinetics, and uncontrolled lithium deposition/stripping remain the main challenges in lithium-sulfur batteries (LSBs), which are aggravated under practical working conditions, i.e., high sulfur loading and lean electrolyte in large-capacity pouch cells.

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Lithium-sulfur (Li-S) batteries exhibit great potential as the next-generation energy storage techniques. Application of catalyst is widely adopted to accelerate the redox kinetics of polysulfide conversion reactions and improve battery performance. Although significant attention has been devoted to seeking new catalysts, the problem of catalyst passivation remains underexplored.

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Article Synopsis
  • Fluspirilene, a classic anti-schizophrenic drug, shows significant potential as a treatment for human glioblastoma (GBM), outperforming perphenazine and sulpiride in anti-GBM effects.
  • Molecular studies show fluspirilene inhibits GBM cell proliferation and migration while increasing apoptosis, particularly affecting U87MG and U251 cell lines.
  • The drug's mechanism involves downregulating KIF20A through the oncogenic transcription factor FOXM1, indicating its role in the suppression of growth in GBM cells.
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Background: This study aims to investigate the relationship between older adults' perceived community services for the elderly (PCSE), life satisfaction (LS), and self-rated health (SRH).

Methods: Data from four rounds of the Chinese Longitudinal Healthy Longevity Survey (CLHLS) from 2008 to 2018 were used. A total of 2454 older adults were obtained.

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Objective: To compile a scale of Chinese college students' perception of teachers' differential behavior and to provide a reference for college students to establish correct life values, promote college students' physical and mental health, and reduce teachers' differential treatment.

Methods: Open-ended questionnaires and expert interviews were used to conduct interviews and correspondence with 58 college students, ten psychologists, and six psychologists to form an initial questionnaire. Then, the scale's exploratory factor analysis, confirmatory factor analysis, and reliability and validity test were conducted on 7053 college students from 18 universities in 6 provinces (municipalities directly under the Central Government).

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Aims: Surgical resection is the primary treatment option for patients diagnosed with nonfunctional pancreatic neuroendocrine tumors (NF-Pan-NETs). However, the postoperative prognostic evaluation for NF-Pan-NET patients remains obscure. This study aimed to construct an efficient model to predict the prognosis of NF-Pan-NET patients who have received surgical resection.

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  • Patient-specific induced pluripotent stem cell-derived (iPSC-derived) cell lines offer tailored therapies, enhancing treatment precision for conditions like Bietti crystalline dystrophy (BCD), a rare blinding disease affecting around 67,000 people globally.
  • The study utilized iPSC-derived retinal pigment epithelium (iRPE) cells from BCD patients to assess the effectiveness of adeno-associated virus (AAV)-mediated gene therapy, finding that this therapy can significantly reduce blue light-induced cell death in affected cells.
  • Additionally, the researchers discovered variability in cellular phenotypes linked to different genetic mutations, highlighting the importance of personalized treatment approaches in advancing therapies for BCD and potentially other diseases.
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Lithium-sulfur (Li-S) batteries enable a promising high-energy-storage system while facing practical challenges regarding lithium dendrites and lithium polysulfides (LiPSs) shuttling. Herein, a fascinating SOH-functionalized graphdiyne (SOGDY) was developed by grafting SOH onto GDY to modify the separator in Li-S batteries. It realizes structure-retained material transformation, that is, SOGDY retains the crystalline all-carbon network and uniform subnanopores from the initial GDY.

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The intriguing characteristics of two-dimensional (2D) heterostructures stem from their unique interfaces, which can improve ion storage capability and rate performance. However, there are still challenges in increasing the proportion of heterogeneous interfaces in materials and understanding the complex interaction mechanisms at these interfaces. Here, we have successfully synthesized confined CoSe within the interlayer space of TiCT through a simple solvothermal method, resulting in the formation of a superlattice-like heterostructures of CoSe@TiCT.

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Background: Bibliometric analysis of liver cancer research, particularly in immunotherapy, reveals crucial insights. The US leads in liver cancer mortality but ranks fifth globally.

Objective: Scopus database analysis identified 2,349 papers, with the top 100 ranging from 127 to 4,959 citations.

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Purpose: The purpose of this study was to establish and validate machine learning-based models for predicting the risk of venous thromboembolism (VTE) in intensive care unit (ICU) patients.

Patients And Methods: The clinical data of 1494 ICU patients who underwent Doppler ultrasonography or venography between December 2020 and March 2023 were extracted from three tertiary hospitals. The Boruta algorithm was used to screen the essential variables associated with VTE.

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Article Synopsis
  • China is facing a healthcare challenge due to its aging population, prompting the need for an integrated old-age healthcare system that considers the interests of various stakeholders.
  • The study aims to resolve conflicts among stakeholders by using conflict resolution strategies, including stakeholder analysis and decision-making techniques like the Analytic Hierarchy Process (AHP).
  • Recommendations emphasize the distribution of authority, simplifying procedures, improving the insurance system, expanding services, and ensuring elderly individuals actively participate in their healthcare decisions to enhance care delivery.
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  • Global warming has led to an increase in atmospheric moisture, particularly in the Arctic, but the specifics of polar precipitation events are still not well understood due to a lack of data.
  • This study uses GPM satellite data and ERA5 reanalysis data to analyze summer precipitation at the northern margin of the Eurasian region and the role of cyclone activity in influencing this precipitation.
  • Findings indicate that the northern margin experiences high precipitation, mainly from cyclonic activity, with significant differences in contributions between GPM and ERA5 data, revealing that stronger summer cyclones lead to more intense precipitation events.
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  • Some lactic acid bacteria (LAB) have health benefits essential for the conservation of endangered animals, specifically giant pandas, but their diversity in pandas' gut microbiota is largely unexplored.
  • The researchers created a culture pipeline to isolate and study LAB strains from giant pandas using various growth conditions, resulting in a significant collection of bacterial strains.
  • The study revealed that the cultured bacteria were more diverse than those found in culture-independent methods, laying groundwork for future research on LAB's potential health benefits and probiotic applications in conservation efforts.
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Introduction: The burden of colorectal cancer (CRC) plays a pivotal role in the global cancer epidemic. Our study reported the incidence trends in CRC and the associated effects of age, period, and birth cohort in 204 countries and territories over the past 30 years.

Methods: The incidence data of CRC were extracted from the Global Burden of Disease Study (GBD) 2019.

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Background: Keloids are excessive formations of scar tissue that develop at the site of a skin injury. Due to their invasive nature, they have a negative impact on the skin's appearance and are prone to recurrence, making them a challenging condition to treat with regard to skin aesthetics.

Objectives: The objective of this article was to compare the long-term effects of dermatologic trephination with nonsurgical treatments for scars and evaluate the clinical value of the treatments.

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The purpose of this study was to investigate the antibacterial activity and mechanism of action of osthole against . The antibacterial activity of osthole was evaluated by determining the minimum inhibitory concentration (MIC) and growth curve. Cell morphology, membrane permeability, membrane integrity, bacterial physiology, and metabolism were explored using different methods to elucidate the mechanism of action of osthole.

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Background: Fibronectin type III domain containing 3B (FNDC3B), a member of the fibronectin type III domain-containing protein family, has been indicated in various malignancies. However, the precise role of FNDC3B in the progression of pancreatic cancer (PC) still remains to be elucidated.

Methods: In this study, we integrated data from the National Center for Biotechnology Information, the Cancer Genome Atlas, Genotype-Tissue Expression database, and Gene Expression Omnibus datasets to analyze FNDC3B expression and its association with various clinicopathological parameters.

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CoS has been extensively studied as a promising catalyst for water electrolysis. Doping CoS with Fe improves its oxygen evolution reaction (OER) performance by regulating the catalyst self-reconfigurability and enhancing the absorption capacity of OER intermediates. However, the poor alkaline hydrogen evolution reaction (HER) properties of CoS limit its application in bifunctional water splitting.

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Background: The rarity yet high malignancy of gallbladder adenocarcinoma (GBA) endows it with a distinctive nature. Radical resection remains the foremost therapeutic approach for GBA, while the impact of early recurrence and metastasis on patient prognosis necessitates the utilization of adjuvant chemotherapy (AC). Despite numerous previous studies on this topic, a consensus regarding the authentic efficacy of AC has yet to be reached.

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  • The study aimed to explore whether adiponectin levels are causally linked to trigeminal neuralgia (TN) using a two-sample Mendelian Randomization approach.
  • Data was gathered from the UK Biobank and FinnGen, analyzing genetic variations to assess the relationship between adiponectin and TN.
  • Results indicated a potential causal association between lower adiponectin levels and increased TN risk, though some analysis methods showed conflicting results, highlighting the complexity of the relationship.
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Reducing doctor-patient conflict is an important part of coordinating doctor-patient disputes and easing doctor-patient relationship, which is conducive to building a harmonious medical environment and promoting the healthy development of medical undertakings. This paper constructs a multi-decision-maker mixed conflict model based on rough set theory, puts forward the matrix operation expression of the conflict degree theory in the Pawlak model, and gives a more objective and scientific evaluation function. Combined with hot issues of doctor-patient conflict, the proposed multi-decision-maker mixed conflict model is applied to doctor-patient conflict, examines the doctor-patient relationship in the medical institution system from multiple internal perspectives, and calculates feasible solutions in the conflict system.

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The aim of this study was to examine the expression changes of HS, IGF-1, and GH in traumatic brain injury (TBI) patients and to detect their neuroprotective functions after TBI. In this study, we first collected cerebrospinal fluid (CSF) and plasma from TBI patients at different times after injury and evaluated the concentrations of HS, IGF-1, and GH. In vitro studies were using the scratch-induced injury model and cell-cell interaction model (HT22 hippocampal neurons co-cultured with LPS-induced BV2 microglia cells).

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Osteosarcoma (OS) is a highly aggressive form of bone cancer that predominantly affects adolescents and young adults. In this study, we have undertaken an investigation into the potential anti-OS cell activity of IMT1 (inhibitor of mitochondrial transcription 1), a first-in-class inhibitor of RNA polymerase mitochondrial (POLRMT). IMT1 exhibited a profound inhibitory effect on cell survival, proliferation, cell cycle progression, and migration in primary and immortalized OS cells.

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Natural Resource Protection (NRP) has been on the agenda of the Sustainable Development Goals (SDGs) and is considered a pathway to sustainable development. The analysis of the determinants of NRP has received the attention of policymakers in framing evidence-based policies and strategies. Renewable energy (RE) is a major contributor to natural resource protection.

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