Two-dimensional inverse double sandwich CoB: strain-induced non-magnetic to ferromagnetic transition.

A full-scale structural search was performed using density functional theory calculations and a universal structural prediction evolutionary algorithm. This produced a lowest energy two-dimensional (2D) CoB structure. The CoB-1 global minimum structure has unusual inverse double sandwich features.

Recent Advances in Radical Coupling Reactions Directly Involving Bicyclo[1.1.1]pentane (BCP).

BCP (bicyclo[1.1.1]pentane) is an ideal saturated carbon bioisostere, instead of the traditional benzene group, which has been extensively developed.

Ultrahigh Selectivity HS Gas Sensor Based CsPbBr Perovskites via Pb-S Bonding Interaction.

High selectivity and sensitivity sensing of HS gas play a decisive role in the early detection of sulfide solid-state battery failure. Herein, we construct the CsPbBr perovskite-based sensor that exhibits outstanding gas-sensing performance to HS at room temperature, including high selectivity, fast response/recovery speed (73.5/275.

High-Performance Dual-Mode UV Photodetection from a Single Maneuverable X-Shaped CsCuI Microcrystal.

Ultraviolet photodetectors (UV PDs) based on microcrystals (MCs) have attracted extensive attention due to their outstanding detection performance. Nevertheless, precise manipulation of the MCs still remains challenging, which may hinder the mass processing and performance improvement of the UV PDs. In this work, a single high-quality CsCuI MC that had a special X-shaped morphology was demonstrated to be successfully manipulated to prepare high-performance UV PDs by virtue of optical focusing, probe micromanipulation, and direct-write photolithography techniques.

Embryoid body-based differentiation of human-induced pluripotent stem cells into cells with a corneal stromal keratocyte phenotype.

Objective: The transparency of the cornea is determined by the extracellular matrix, which is secreted by corneal stromal keratocytes (CSKs). Human-induced pluripotent stem cell (hiPSC)-derived keratocytes (hiPSC-CSKs) can be used in cell-based therapy for treating corneal blindness. Our goal was to develop an effective small molecule-based technique for differentiating hiPSCs into keratocytes.

Colorectal cancer screening using a multi-locus blood-based assay targeting circulating tumor DNA methylation: a cross-sectional study in an average-risk population.

Background: Effective screening for colorectal cancer (CRC) enables earlier diagnosis and intervention to improve patient survival.

Methods: In this study, we prospectively conducted a blood-based CRC screening program for community residents in Hanjiang District, Yangzhou City, and evaluated the screening efficacy of a blood-based multi-locus DNA methylation assay (ColonAiQ). The ColonAiQ-positive rate and colonoscopy participation rate of the population, detection rate of intestinal lesions, and positive predictive value (PPV) of CRC and advanced adenoma (AA) were calculated, and the associated factors were explored.

A pan-cancer analysis of the oncogenic function of HMGB1 in human tumors.

Background: Although high mobility group box protein 1 () has been researched in relation to cancer in many investigations, a thorough investigation of its role in pan-cancer has yet to be conducted. With the objective of bridging this gap, we delved into the functions of in various tumors.

Methods: This investigation employed The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases to examine gene expression differences and correlation with survival across various human tumors.

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Nano-titanium dioxide (Nano-TiO) is extensively utilized across various industries and has the capacity to penetrate human tissues through multiple biological barriers. The HaCaT cell line, as one of human immortalized keratinocytes, is usually used as a model for studying skin drug toxicology. The objective was to assess the toxic effects of nano-TiO on HaCaT cells and to trigger pyroptosis.

Nickel-Catalyzed Cross-Electrophile Vinylation of α-Chloro Phosphonates.

Herein, we report a general and efficient Ni-catalyzed reductive cross-coupling reaction of substituted vinyl bromides and α-chloro phosphonates to access a set of α-vinyl phosphonates using zinc as the terminal reductant. This reaction exhibits broad substrate adaptability and good functional group tolerance, which allows to afford diverse compounds including structurally complex motifs from natural products and drugs. Furthermore, the practicality was certificated through the gram-scale and transformation experiments.

Pore-edge high active sites of 2D WO nanosheets enhancing acetone sensing performance.

The precise and timely detection of acetone is crucial for ensuring industrial production safety and for clinical diagnosis of diabetes. Therefore, developing acetone sensors with high performance is increasingly important. This work successfully introduced nano-scale holes into two-dimensional (2D) WO nanosheets by topological transformation and in-situ oxidation.

Exploring the spatiotemporal patterns of county-scale PM2.5 drivers in Shandong Province from 2000 to 2020.

In the rapid development of air pollution over the past two decades in Shandong Province, it has played a detrimental role, causing severe damage to regional ecological security and public health. There has been little research at the county scale to explore the spatiotemporal causes and heterogeneity of PM2.5 pollution.

Photoelectrocatalytic CO Reduction to Formate Using a BiVO/ZIF-8 Heterojunction.

Converting CO into high-value chemical fuels through green photoelectrocatalytic reaction path is considered as a potential strategy to solve energy and environmental problems. In this work, BiVO/ZIF-8 heterojunctions are prepared by in-situ synthesis of ZIF-8 nanocrystals with unique pore structure on the surface of BiVO. The experimental results show that the silkworm pupa-like BiVO is successfully combined with porous ZIF-8, and the introduction of ZIF-8 can provide more sites for CO capture.

Association between breastfeeding duration and neurodevelopment in Chinese children aged 2 to 3 years.

Objective: The aim of this study was to explore the relationship between breastfeeding duration and neurodevelopment in children aged 2 to 3 years in a Chinese population.

Methods: This study was based on a cross-sectional survey. The data were from the National Nutrition and Health Systematic Survey for children in China which was conducted from 2019 to 2020.

Redox Activity of Co Species in the Active Sites of CoN/CoO Facilitates Oxygen Electrocatalysis for Zn-Air Batteries.

Developing efficient bifunctional oxygen electrocatalysts is crucial for enhancing the performance of rechargeable Zn-air batteries (ZABs). In this study, cobalt/cobalt oxides embedded in N-doped carbon nanofibers (Co/CoO/NCNFs) were synthesized through a combination of electrospinning and annealing processes. The resulting Co/CoO/NCNFs catalysts feature abundant CoN and CoO active species, leveraging the large specific surface area of nanofibers to facilitate oxygen reduction reaction (ORR) and oxygen evolution reaction (OER).

Aldehyde dehydrogenase 2 preserves kidney function by countering acrolein-induced metabolic and mitochondrial dysfunction.

The prevalence of chronic kidney disease (CKD) varies by race because of genetic and environmental factors. The Glu504Lys polymorphism in aldehyde dehydrogenase 2 (ALDH2), commonly observed among East Asian people, alters the enzyme's function in detoxifying alcohol-derived aldehydes, affecting kidney function. This study investigated the association between variations in ALDH2 levels within the kidney and the progression of kidney fibrosis.

Puzzle Hi-C: An accurate scaffolding software.

High-quality, chromosome-scale genomes are essential for genomic analyses. Analyses, including 3D genomics, epigenetics, and comparative genomics rely on a high-quality genome assembly, which is often accomplished with the assistance of Hi-C data. Curation of genomes reveal that current Hi-C-assisted scaffolding algorithms either generate ordering and orientation errors or fail to assemble high-quality chromosome-level scaffolds.

Research Progress on Mechanical Strength of Rice Stalks.

As one of the most important food crops in the world, rice yield is directly related to national food security. Lodging is one of the most important factors restricting rice production, and the cultivation of rice varieties with lodging resistance is of great significance in rice breeding. The lodging resistance of rice is directly related to the mechanical strength of the stalks.

Construction of a novel nomogram for predicting overall survival in patients with Siewert type II AEG based on LODDS: a study based on the seer database and external validation.

Background: In recent years, the incidence of adenocarcinoma of the esophagogastric junction (AEG) has been rapidly increasing globally. Despite advances in the diagnosis and treatment of AEG, the overall prognosis for AEG patients remains concerning. Therefore, analyzing prognostic factors for AEG patients of Siewert type II and constructing a prognostic model for AEG patients is important.

Strength Enhancement of Polyurethane Film by Solution Annealing.

Recently, polyurethane elastomer (TPU) has attracted more and more attention depending on its excellent optical, mechanical, and retreatment properties. The high strength of polyurethane has always been pursued, which can enable its application in more fields. In this work, an aliphatic polyurethane elastomer membrane (HRPU6) was successfully synthesized, and its strength was obviously improved by solvent annealing technology.

Constructing Built-in-Electric Field for Boosting Electrocatalytic Water Splitting.

Electrocatalytic water splitting shows great potential for producing clean and green hydrogen, but it is hindered by slow reaction kinetics. Advanced electrocatalysts are needed to lower the energy barriers. The establishment of built-in electric fields (BIEF) in heterointerfaces has been found to be beneficial for speeding up electron transfer, increasing electrical conductivity, adjusting the local reaction environment, and optimizing the chemisorption energy with intermediates.