Publications by authors named "Yang Henghui"
Intraperitoneal dissemination is the main method of epithelial ovarian cancer (EOC) metastasis, which is related to poor prognosis and a high recurrence rate. Circular RNAs (circRNAs) are a novel class of endogenous RNAs with covalently closed loop structures that are implicated in the regulation of tumor development. In this study, hsa_circ_0001546 is downregulated in EOC primary and metastatic tissues vs.
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- Ovarian cancer (OC) is a prevalent malignant tumor in females, with a focus on glutamine metabolism-related genes (GMRGs) that influence its progression.
- The research utilized multiple databases (TCGA, GTEx, and GEO) to analyze OC samples, identifying differentially expressed genes (DEGs) and constructing a risk model based on GMRGs that are linked to survival.
- Key findings include the identification of 9 GMRGs-related DEGs, potential biomarkers like NKD2 and C2orf88 for prognosis, and notable differences in immune cell types across varying risk groups, suggesting diverse tumor microenvironments based on metabolic subtypes.