Uniparental disomy (UPD) is when all or part of the homologous chromosomes are inherited from only one of the two parents. Currently, UPD has been reported to occur for almost all chromosomes. In this study, we report two cases of UPD for chromosome 2 (UPD2) encountered during prenatal diagnosis.
View Article and Find Full Text PDFSurface-enhanced Raman scattering (SERS) spectroscopy aims to augment the relatively weak molecular vibrations based on electromagnetic enhancement (EE) and chemical enhancement (CE) mechanisms, and offers a potential way for material identification, even up to the single-molecule level, under atmospheric conditions. We have subtly combined the advantages of EE and CE, and propose new MXene (Ti3C2TX) nano-sheet/Au nanostructure architectures to break through the limitations of the Raman detection with long-time stability. The MXene nanosheets with excellent biocompatibility can effectively prevent structural distortion from the interaction with the Au NSs, and can also guarantee a high enhancement effect owing to the spatially extended electromagnetic field distribution and electron injection into the molecules.
View Article and Find Full Text PDFThe structural, magnetic, electrical and dielectric properties of an Ir-based double perovskite compound, LaCoIrO, have been investigated. The sample undergoes a paramagnetic-ferromagnetic transition at T, followed by a reentrant spin-glass transition at lower temperatures. The reentrant spin glass state in LaCoIrO is associated with the competitions of the antiferromagnetic coupling between Ir and Co ions and the ferromagnetic clusters.
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