Publications by authors named "Yanfang Yao"

The epigenetic reader SntB was identified as an important transcriptional regulator of growth, development, and secondary metabolite synthesis in . However, the underlying molecular mechanism is still unclear. In this study, by gene deletion and complementation, we found SntB is essential for mycelia growth, conidial production, sclerotia formation, aflatoxin synthesis, and host colonization.

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is one of the common pests of fruit trees, but the research on the pathogenic microorganisms it may carry is very limited. Therefore, it is essential to reveal the pathogenic microbes it carries and their potential hazards. This study found a new virus from the transcriptome of , which was first reported in and named PyCaV ( associated virus).

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The main impediment to the development of zinc-air batteries is the sluggish kinetics of the oxygen reduction reaction (ORR) and the oxygen evolution reaction (OER). Transition metal N-doped carbon catalysts offer a promising alternative to noble metal catalysts, with metal-organic framework (MOF)-derived carbon material catalysts being particularly noteworthy. Here, we synthesized MP-Z-C carbon catalysts by combining two-dimensional (2D) metal porphyrin-based MOFs (MPMFs, x = Fe, Co, Ni, Mn) and three-dimensional zeolitic imidazole framework-8 (ZIF-8) through electrostatic interaction, followed by carbonization.

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RNA modifications play key roles in eukaryotes, but the functions in are still unknown. Temperature has been reported previously to be a critical environmental factor that regulates the aflatoxin production of , but much remains to be learned about the molecular networks. Here, we demonstrated that 12 kinds of RNA modifications in were significantly changed under 29 °C compared to 37 °C incubation; among them, m6A was further verified by a colorimetric method.

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As a filamentous pathogenic fungus with high-yield of aflatoxin B, is commonly found in various agricultural products. It is crucial to develop effective strategies aimed at the prevention of the contamination of and aflatoxin. Hexokinase AfHxk1 is a critical enzyme in fungal glucose metabolism.

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Article Synopsis
  • Aspergillus flavus is a type of fungus that can make people sick because it produces a harmful chemical called aflatoxin B1 (AFB).
  • Scientists are studying a protein called Set9, which helps control how this fungus grows and produces toxins.
  • By understanding how Set9 works, researchers hope to find new ways to prevent contamination from this dangerous fungus and keep food safe.
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As the main producer of aflatoxins, Aspergillus flavus is also one of the most important causes of invasive and non-invasive aspergillosis. Therefore, it is crucial to unravel the regulatory mechanisms of growth, metabolism, and pathogenicity of A. flavus.

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A mild copper-catalyzed four-component selenosulfonylation of alkynes, cycloketone oxime esters, DABCO (SO) and diselenides has been developed. This method enables the rapid assembly of β-cyanoalkylsulfonylated vinyl selenides in moderate to good yields. Advantages of this protocol include a broad substrate scope, good functional group tolerance and the late-stage functionalization of complex molecules.

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A photoinduced three-component reaction of N-benzyl-N-(2-ethynylaryl)amides, sulfur dioxide and aryldiazonium tetrafluoroborates is developed, providing an efficient and straightforward approach for the synthesis of diverse vinylsulfonylated dibenzazepine derivatives in moderate to good yields under mild conditions. This transformation proceeds smoothly at room temperature in the presence of visible light, which shows a wide range of substrate scope with good functional group compatibility. The synthetic utility of this methodology is further demonstrated through Suzuki coupling.

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A photoredox-catalyzed three-component reaction of aryldiazonium tetrafluoroborates with sodium metabisulfite and 2,2-difluoro enol silyl ethers is described. By using sodium metabisulfite as the source of sulfur dioxide, this method provides an elegant access to α,α-difluoro-β-ketosulfones in moderate to good yields under mild conditions, and features a broad substrate scope and wide functional group tolerance. Both of the difluoromethyl group and sulfone moiety can be introduced in a single step.

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