Investigating the types of eating behavior among shift workers in the machine-building industry.

Shift work has become the norm and an absolute necessity in various sectors of public life. Different production processes, technologies, and the nature of certain jobs lead to various health risks. Unhealthy eating behaviors remain common among shift workers across all economic sectors.

(3D) Bioprinting-Next Dimension of the Pharmaceutical Sector.

To create a review of the published scientific literature on the benefits and potential perspectives of the use of 3D bio-nitrification in the field of pharmaceutics. This work was performed in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines for reporting meta-analyses and systematic reviews. The scientific databases PubMed, Scopus, Google Scholar, and ScienceDirect were used to search and extract data using the following keywords: 3D bioprinting, drug research and development, personalized medicine, pharmaceutical companies, clinical trials, drug testing.

Unlocking the Future: Bioprinting Salivary Glands-From Possibility to Reality.

Salivary gland biofabrication represents a promising avenue in regenerative medicine, aiming to address the challenges of salivary gland dysfunction caused by various factors such as autoimmune diseases and radiotherapy. This review examines the current state of bioprinting technology, biomaterials, and tissue engineering strategies in the context of creating functional, implantable salivary gland constructs. Key considerations include achieving vascularization for proper nutrient supply, maintaining cell viability and functionality during printing, and promoting tissue maturation and integration with surrounding tissues.

The role of postoperative trimetazidine therapy in on-pump coronary artery bypass surgery.

Coronary artery bypass surgery remains the gold standard in the treatment of patients with ischemic heart disease. However, the increased oxidative stress caused by the release of free radicals during the ischemia-reperfusion time is a well-known pathophysiological process during and after coronary revascularization procedures. It may lead to reversible and irreversible myocardial injury.

Advancing Dentistry through Bioprinting: Personalization of Oral Tissues.

Despite significant advancements in dental tissue restoration and the use of prostheses for addressing tooth loss, the prevailing clinical approaches remain somewhat inadequate for replicating native dental tissue characteristics. The emergence of three-dimensional (3D) bioprinting offers a promising innovation within the fields of regenerative medicine and tissue engineering. This technology offers notable precision and efficiency, thereby introducing a fresh avenue for tissue regeneration.

The Progress in Bioprinting and Its Potential Impact on Health-Related Quality of Life.

The intensive development of technologies related to human health in recent years has caused a real revolution. The transition from conventional medicine to personalized medicine, largely driven by bioprinting, is expected to have a significant positive impact on a patient's quality of life. This article aims to conduct a systematic review of bioprinting's potential impact on health-related quality of life.

Cytokine profile in patients with acute bacterial meningitis.

Background: Bacterial meningitis is a life-threatening disease with high mortality and common long-term sequelae. The inflammatory response in the subarachnoid space, modulated by different cytokines, plays a major role in the pathogenesis of acute central nervous system infections. We aimed to examine correlations of interleukin (IL)-6, IL-8, IL-10, IL-12(p40), and tumor necrosis factor (TNF)-α levels with disease severity, complications, and outcome in patients with acute bacterial meningitis.

(Bio)printing in Personalized Medicine-Opportunities and Potential Benefits.

The global development of technologies now enters areas related to human health, with a transition from conventional to personalized medicine that is based to a significant extent on (bio)printing. The goal of this article is to review some of the published scientific literature and to highlight the importance and potential benefits of using 3D (bio)printing techniques in contemporary personalized medicine and also to offer future perspectives in this research field. The article is prepared according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.

Influence of rehabilitation on mental state in patients with lumbar intervertebral disc damage.

The present study aims to investigate the mental state changes in patients with lumbar intervertebral disc damage after rehabilitation program using a self-administered questionnaire IRES-3. The study was conducted in the Specialized Hospitals for Rehabilitation - National Complex EAD, branches Hissar and Banite, Bulgaria. It included 124 patients - 34 men and 90 women, aged from 35 to 85 years.

The architecture of the hybrid lab: Spacing graphene research.

Building on and renewing a long line of STS research of lab materialities, this article sheds light on a type of architecture organized around the 'heroic agency' of a new nanomaterial, graphene. It examines how design responds to the dynamic and multi-applicational ambitions of contemporary science. An ethnographic study of the National Graphene Institute in Manchester allows us to see how the building's design has epistemic and social effects, how different spatial arrangements facilitate the shaping of research habits and mediate various rhythms of lab work.

Initial Adaptation of the General Cognitive Assessment Battery by Cognifit™ for Bulgarian Older Adults.

Background: Online neuropsychological assessment batteries may facilitate the screening of cognitive functions in older adults and could be useful for early diagnosis and detection of cognitive impairments.

Objective: The primary aim of this study was to assess the psychometric qualities of an online multi-domain cognitive assessment battery (General Cognitive Assessment Battery (GCAB) by Cognifit™) applied for the first time in Bulgaria.

Methods: A total of 20 healthy older adults (6 male and 14 female, aged 60-82) completed the GCAB as well as the Mini-Mental State Examination (MMSE) and the Consortium to Establish a Registry for Alzheimer's Disease (CERAD) neuropsychological battery.

Strategic investment in tuberculosis control in the Republic of Bulgaria.

As Bulgaria transitions away from Global Fund grant, robust estimates of the comparative impact of the various response strategies under consideration are needed to ensure sustained effectiveness of the tuberculosis (TB) programme. We tailored an established mathematical model for TB control to the epidemic in Bulgaria to project the likely outcomes of seven intervention scenarios. Under existing programmatic conditions projected forward, the country's targets for achieving TB elimination in the coming decades will not be achieved.

Staging scientific controversies: a gallery test on science museums' interactivity.

The "transfer" model in science communication has been addressed critically from different perspectives, while the advantages of the interactive model have been continuously praised. Yet, little is done to account for the specific role of the interactive model in communicating "unfinished science." The traditional interactive methods in museums are not sufficient to keep pace with rapid scientific developments.

Assessment of the working-environment harmful factors and health risk of workers in a nitrogen fertilizer plant.

The authors examined the influence of harmful factors of the working environment such as: microclimate, dust, noise, vibrations, and chemical noxes such as: ammonia, nitric oxides, hydrogen fluoride and gaseous fluorides, on the health status of workers involved in the production of fertilizers and ammonia in a nitrogen fertilizer plant. Various biochemical examinations of 158 workers were carried out. The morbidity rate for 1993-1995 was also studied.