Pathological changes of renal biopsy in Sjögren Syndrome.

We are presenting the case of a 53-year-old woman with a history of Sjögren syndrome and a secondary antiphospholipid syndrome admitted at the Nephrology department for the evaluation of renal failure. The patient was initially diagnosed with tubulointerstitial nephritis and subsequently a membranoproliferative type I glomerulonephritis, secondary to cryoglobulins during the course of the disease. Repeated renal biopsies were required to confirm the diagnosis.

Antinociceptive Activity of Methanol Extract of Tabebuia hypoleuca (C. Wright ex Sauvalle) Urb. Stems.

Objective: The aim of this study was to evaluate the antinociceptive activity of the methanol extract of Tabebuia hypoleuca stems (THME).

Materials And Methods: The animals were divided into 5 groups of 8 mice for each test (negative controls, positive controls, and 3 groups treated with THME at doses of 150, 300, and 500 mg/kg, p.o.

Prasugrel and Acquired Thrombotic Thrombocytopenic Purpura Associated with ADAMTS13 Activity Deficiency.

Unlabelled: We report a case of a 64-year-old man who, 44 days after starting treatment with prasugrel, presented with severe thrombocytopenia, anaemia, renal failure, and severe ADAMTS13 activity deficiency, along with a high titer of autoantibodies to this protease.

Learning Points: Drug-induced TTP is a rare condition and difficult to diagnose.Decreased activity of ADAMTS13, unusual in drug-induced TTP, was present in this case.

Polychlorinated biphenyls (PCBs) residues in milk from an agroindustrial zone of Tuxpan, Veracruz, Mexico.

The coasts of the Gulf of Mexico are zones exposed to the exploration and exploitation of petroleum sources, and the products generated in agricultural zones may become contaminated by persistent organic pollutants (POPs). The objective of the present study was to evaluate the presence of polychlorinated biphenyl compounds (PCBs) in milk from dairy production units near sources of environmental pollutants. It was confirmed that the seven congeners of nondioxin-like PCBs (NDL-PCBs) are present in milk where compounds PCB101, PCB118, PCB153 and PCB180 appear in 100% of the samples analyzed, the rank of concentration for the sum of the seven congeners fluctuating between 2.