Publications by authors named "Yanen Leng"

Article Synopsis
  • Neurological disorders are becoming a significant global health issue, especially due to an aging population and are linked to factors like inflammation and oxidative stress.
  • Curcumin, a natural compound from turmeric, shows promise as a potent antioxidant that can help counteract oxidative stress and its damaging effects on neuronal cells.
  • The review highlights the potential of curcumin in treating various neurological conditions, such as depression and Alzheimer's, suggesting it may offer new therapeutic options for managing these disorders.
View Article and Find Full Text PDF

Background: Elagolix, an approved non-peptide GnRH antagonist, shows promise in relieving endometriosis-related pain, but its short- and mid-term efficacy and potential side effects are still under investigation.

Objective: The aim is to provide data for therapeutic applications by methodically evaluating elagolix's safety and effectiveness in treating endometriosis-related pain.

Methods: Databases such as PubMed, Embase, Cochrane Library, Web of Science, ClinicalTrials.

View Article and Find Full Text PDF

Background: Given the ongoing COVID-19 pandemic, it is crucial to prioritize the management of underlying diseases in infected patients, with hypertension being one of the most common conditions. However, there lies a complicated correlation between antihypertensive agents and COVID-19 infection.

Objectives: This study is to systematically evaluate the impact of continuing or discontinuing antihypertensive agents on mortality and infection severity in hospitalized patients with both hypertension and COVID-19.

View Article and Find Full Text PDF

Methylphenidate, atomoxetine, and Amphetamine are the three most commonly used medications approved by the United States Food and Drug Administration (FDA) for the treatment of attention deficit/hyperactivity disorder (ADHD). However, a comprehensive analysis of their safety profiles across various age groups and genders in real-world contexts has yet to be conducted. In this study, a pharmacovigilance analysis was performed using the FDA Adverse Event Reporting System (FAERS) database to examine differences in adverse events between methylphenidate, atomoxetine, and Amphetamine.

View Article and Find Full Text PDF