Publications by authors named "Yane Lu"
Article Synopsis
- Mitochondria play a crucial role in energy production and regulating processes like oxidative stress and cell death; mtDNA is vital for their function, leading to interest in its link to mental disorders.
- This study used genetic data from large biobanks to analyze whether changes in mtDNA copy number (mtDNA-CN) are causally related to mental disorders, including ASD, schizophrenia, and bipolar disorder, using advanced statistical methods.
- The findings showed a significant decrease in autism risk linked to higher mtDNA-CN levels, with no causal connections found for other mental disorders, suggesting mtDNA-CN could be a useful early screening marker for autism spectrum disorder.
Article Synopsis
- This study explores the impact of virtual reality-based cognitive-behavioral therapy (VR-CBT) on anxiety symptoms in patients who experienced acute myocardial infarction (AMI) while in the ICU.
- A randomized clinical trial with 148 participants showed that those receiving VR-CBT alongside standard support reported significantly reduced anxiety symptoms compared to those who only received standard support, as measured by the Hamilton Anxiety Rating Scale.
- The intervention was well-completed by 88.6% of the participants in the VR-CBT group, indicating a promising approach to improving mental health in acute cardiac care settings.
Purpose: To make early detection of individuals with autism spectrum disorder (ASD), caregiver-report instruments remain an efficient and adaptable option for the preliminary assessment. This study aimed to compare the psychometric properties of the Clancy Autism Behavior Scale (CABS) and Autism Behavior Checklist (ABC) as screening tools for ASD by caregivers.
Methods: The data were collected from 154 pairs of children and their parents, who sought medical attention for suspected autism at Peking University Sixth Hospital.
Background: Acceptance and commitment therapy (ACT) is a promising intervention for improving mental health. However, there is limited evidence on its effectiveness for nurses, particularly in web- and mobile-based intervention forms, in mitigating anxiety and depression symptoms.
Objective: In this study, we aimed to examine the effect and underlying psychological mechanisms of a web- and mobile-based ACT intervention on nurses' anxiety and depression symptoms.
Intimate partner violence (IPV) against women presents a major public health challenge, especially in low-income and middle-income countries (LMICs), and its relationship with poor offspring growth is emerging but remains understudied. This study aimed to explore the impact of maternal exposure to IPV on offspring growth based on different approaches in LMICs. We conducted a population-based cross-sectional study using the most recent Demographic and Health Surveys from 32 LMICs; 81,652 mother-child dyads comprising women aged from 15 to 49 years with children aged 0 to 59 months were included.
View Article and Find Full Text PDFExposure to a poor intrauterine environment, such as maternal prenatal stress, has been linked to gut microbiota health in infants. Understanding the link between maternal prenatal bonding, early gut microbiota, and neuropsychological development may promote healthy development in early life. This study included 306 mother-child pairs.
View Article and Find Full Text PDFInfant neglect is a common type of child maltreatment. According to the Social Information Processing theory, maternal executive function (EF) and reflective function (RF) are assumed to be important contributing factors to infant neglect. However, empirical evidence about this assumption is sparse.
View Article and Find Full Text PDFBackground: Women undergoing fertilization-embryo transfer (IVF-ET) treatment were generally found to experience varying degrees of psychological distress across the treatment. Existing studies focused on total scores and diagnostic thresholds to characterize the symptoms' severity, which might hinder scientific progress in understanding and treating psychological distress.
Aims: We aimed to investigate (a) how depression and anxiety symptoms are interconnected within a network, and (b) the changes of the network (symptom connections and network centralities) over time, in women undergoing fertilization-embryo transfer.
Objective: Edinburgh Postnatal Depression Scale (EPDS) was widely used in measuring depression symptoms among pregnant women. However, it is still unclear about the sensitivity to change and minimal clinically important difference (MCID) for EPDS.
Methods: Based on data from an eight-week smartphone-based mindfulness intervention, scores of EPDS, 9-item Patient Health Questionnaire (PHQ-9), and 7-item Generalized Anxiety Disorder (GAD-7) before and after the intervention were collected.