Manipulation of Glutamatergic Neuronal Activity in the Primary Motor Cortex Regulates Cardiac Function in Normal and Myocardial Infarction Mice.

Cardiac function is under neural regulation; however, brain regions in the cerebral cortex responsible for regulating cardiac function remain elusive. In this study, retrograde trans-synaptic viral tracing is used from the heart to identify a specific population of the excitatory neurons in the primary motor cortex (M1) that influences cardiac function in mice. Optogenetic activation of M1 glutamatergic neurons increases heart rate, ejection fraction, and blood pressure.

A content-aware corpus-based model for analysis of marine accidents.

In the past decades, marine accidents brought the serious loss of life and property and environmental contamination. With the accumulation of marine accident data, especially accident investigation reports, compared with subjective reasoning based on expert experience, data-driven methods for analysis and accident prevention are more comprehensive and objective. This paper aims to develop a content-aware corpus-based model for the analysis of marine accidents to mine the accident semantic features.