Publications by authors named "Yanan Zhou"

Accurate and effective monitoring of potentially toxic elements (PTEs) in soil across vast regions is crucial for environmental modeling and public health. While remote sensing (RS) technology provides a promising approach by detecting soil spectrum, dense and persistent vegetation cover in subtropical agricultural areas hinders acquisition of bare soil signals, limiting soil PTEs monitoring. To address this challenge, the present study proposed an innovative method for monitoring soil arsenic (As) content by using vegetation characteristics retrieved from RS data as proxy variables, given soil-vegetation interactions.

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To evaluate the impact of different roughages on the intestinal microbiota of yak calves, we fed them oat hay in substitution of alfalfa hay, in addition to milk replacer and starter powder. Twenty-one 45-day-old male yak calves were selected and randomly assigned to three groups: the milk replacer + starter + alfalfa hay group (AH), the milk replacer + starter + oat hay group (OH), and the milk replacer + starter + mixed hay group (AO), in which the alfalfa hay and oat hay were administered in a 1:1 ratio. All calves in the three groups were fed the same milk replacer and an equivalent amount of dry matter.

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Enhancing the selectivity of photocatalytic CO reduction to valuable multicarbon (C) products remains a significant challenge in green synthetic chemistry. Here, we present a dual-center strategy for metal oxides that boosts the photochemical conversion of CO to ethanol by regulating the coordination number of metal and oxygen sites. Notably, CuO catalysts rich in low-coordinated Cu-O domains have achieved nearly perfect ethanol selectivity (96.

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Multiple intersecting situational tasks in the field of aviation often cause air traffic controllers to face issues pertaining to interruption and task switching. To investigate the impact of task interruption on the situation awareness of air traffic controllers, two experiments were conducted. Experiment 1, which focused on 44 new graduates preparing to work in the field of air traffic control, revealed that task interruption reduced the participants' levels of situation awareness.

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Single-atom catalysts (SACs) are widely employed in Fenton-like catalysis, yet guidelines for their high-performance design remain elusive. The Sabatier principle provides guidance for the ideal catalyst with the highest activity. Herein, the study meticulously engineered a series of SACs featuring a broad distribution of d-band center through single-atom coordination engineering, facilitating a comprehensive exploration of the Sabatier relationship in Fenton-like catalysis.

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Article Synopsis
  • The study developed an intranasal COVID-19 vaccine called RBD-HR, which consists of a receptor binding domain-derived protein and a special oil-in-water adjuvant for enhanced immune response.
  • Testing in mice and rats showed that the vaccine generated strong and long-lasting immune responses, producing high levels of neutralizing antibodies against specific SARS-CoV-2 variants for at least six months.
  • Additionally, the intranasal administration of the vaccine resulted in effective mucosal and systemic immunity, and when used as a booster after mRNA vaccines, it provided better immune responses and protection against live virus challenges.
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Background: Blood coagulation dysfunction is a risk factor for adverse outcomes in patients with coronavirus disease 2019 (COVID-19), especially in severe cases. The evidence for the effects of anticoagulation therapy on prognosis of COVID-19 patients and its risk of causing bleeding events is accumulating. Here we conducted a meta-analysis to assess the efficacy and safety of anticoagulants in COVID-19 patients of different severity.

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The design and development of highly active non-noble metal electrocatalysts for the oxygen evolution reaction (OER) and oxygen reduction reaction (ORR) are crucial for metal-air batteries. In this work, the electrocatalytic performance of different -block metal (PM = Sn, Sb, Pb and Bi) atoms embedded in the g-CN monolayer (PM@g-CN, = 1-3) for the OER and ORR was systematically investigated by density functional theory (DFT). The strong interaction between PM atoms and g-CN substrates indicates the good stability of PM@g-CN catalysts.

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Variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continue to emerge and evade immunity, resulting in breakthrough infections in vaccinated populations. There is an urgent need for the development of vaccines with broad protective effects. In this study, we selected hotspot mutations in the receptor-binding domain (RBD) that contribute to immune escape properties and integrated them into the original RBD protein to obtain a complex RBD protein (cRBD), and we found cRBDs have broad protective effects against SARS-CoV-2 variants.

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  • Gastric cancer (GC) is a common and serious health issue linked to various genetic changes, particularly alterations in DNA methylation patterns.
  • This study analyzes DNA methylation in GC tissues using techniques like the Illumina 935 K BeadChip and bisulfite-pyrosequencing to identify potential diagnostic biomarkers.
  • The findings show significant hypermethylation of the PRKCB gene in GC compared to non-cancerous tissues, indicating a strong connection between DNA methylation changes and GC risk, which could inform future diagnostics and treatments.
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Background: Given the growing acknowledgment of the detrimental effects of excessive myocardial fibrosis on pathological remodeling after myocardial ischemia-reperfusion injury (I/R), targeting the modulation of myocardial fibrosis may offer protective and therapeutic advantages. However, effective clinical interventions and therapies that target myocardial fibrosis remain limited. As a promising chimeric antigen receptor (CAR) cell therapy, whether CAR macrophages (CAR-Ms) can be used to treat I/R remains unclear.

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  • Helicobacter pylori (H. pylori) infection significantly increases the risk of gastric cancer (GC), but the complexities of how this occurs at the cellular level remain unclear.
  • Researchers created a single-cell atlas of gastric tumorigenesis by examining various samples with conditions like gastritis and GC, both with and without H. pylori infection, using advanced single-cell RNA sequencing techniques.
  • The study revealed diverse cellular changes in the progression of gastric cancer, highlighting unique profiles for different cell types and indicating that H. pylori infection enhances cell communication through specific signaling networks, providing new insights into the mechanisms behind H. pylori-induced gastric cancer.
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The study of the cooling efficiency of vegetation in urban residential areas at a micro-scale is important for improving the thermal environment of those areas. The quantitative analysis of the effect of the layout of different building patterns on the cooling efficiency of green space is particularly crucial. This study takes a typical residential area with a row-column arrangement in Jiangning District, Nanjing City, Jiangsu Province, China, as the research object.

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The introduction of competition has the potential to enhance the efficacy of students' learning performance. Nevertheless, there have been contradictory findings about the impact of intergroup competition on students' learning performance and engagement. Therefore, further comprehensive investigations for this problem are necessary.

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Article Synopsis
  • Soluble factors in the upper respiratory tract, specifically a protease called HAT, can help defend against SARS-CoV-2 by reducing its infectivity through cleavage of the virus's spike protein.
  • In studies, infected mice showed increased levels of HAT, which effectively blocked the virus's ability to attach to and fuse with host cells.
  • However, HAT was found to be less effective against the Delta and certain Omicron variants due to mutations near the cleavage site that rendered it resistant.
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  • This study focuses on how different compositions of Pt-Ni alloys can enhance the performance of catalysts for the oxygen reduction reaction (ORR) in proton exchange membrane fuel cells.
  • Using advanced density functional theory calculations, researchers evaluated the ORR activity across various Pt-Ni compositions, finding that the solid solution PtNi(111) is both effective and more affordable compared to pure Pt(111).
  • The standout performer, however, is the Ni/Pt(111) system featuring a single Ni atom, which shows exceptional catalytic activity with a reduced overpotential and stability against segregation, enhancing its effectiveness during the ORR process.
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Background: Wheat (Triticum aestivum L.) is an important grain crops in the world, and its growth and development in different stages is seriously affected by saline-alkali stress, especially in seedling stage. Therefore, nondestructive detection of wheat seedlings under saline-alkali stress can provide more comprehensive technical support for wheat breeding, cultivation and management.

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Foodborne hazardous factors pose a significant risk to public health, emphasizing the need for the development of sensitive and user-friendly detection strategies to effectively manage and control these risks in the food supply chain. Pyrococcus furiosus argonaute (PfAgo)-based biosensing approaches have been extensively explored due to its built-in signal amplification. However, the property that PfAgo is a DNA-guided DNA endonuclease has enabled almost all the existing PfAgo-based reports to be used for the detection of nucleic acids.

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Liver fibrosis is a chronic pathological process in which the abnormal proliferation of connective tissue is induced by various pathogenic factors. During the process of fibrosis, excessive angiogenesis is observed. Physiological angiogenesis has the potential to impede the progression of liver fibrosis through augmenting matrix metalloenzyme activity; however, pathological angiogenesis can exacerbate liver fibrosis by promoting collagen accumulation.

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  • - This study investigates the impact of mixed exposures to polycyclic aromatic hydrocarbons (PAHs) on cognitive functions in older adults, addressing gaps in existing research regarding their potential effects on learning and memory.
  • - Researchers analyzed data from the NHANES database, employing three statistical models to examine the relationship between urinary PAH metabolites and cognitive test scores in individuals aged 60 and older.
  • - Findings revealed that certain PAH metabolites, particularly 2-hydroxynaphthalene (2-OHNa), were negatively associated with performance on cognitive tests, indicating that higher levels of PAHs may lead to poorer cognitive functioning in this age group.
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