Publications by authors named "Yanagida N"
After the Fukushima Daiichi Nuclear Power Station accident, various information about radiation circulated throughout Japan, leading to diverse perceptions regarding the situation in Fukushima. These perceptions contributed to the social challenges faced by the residents of Fukushima at the time, including prejudice and discrimination. This heightened concern about radiation exposure, particularly among younger generations who were considering marriage or starting families.
View Article and Find Full Text PDFBackground: Low-dose (LD) oral food challenge (OFC) with heated cow's milk (CM; 3 mL) effectively prevents CM elimination in children with CM allergy (CMA). We investigated the long-term prognoses after an LD-OFC for CMA.
Methods: Children with immediate CMA symptoms after consuming <25 mL of CM within 2 years of a baseline LD-OFC were retrospectively analyzed.
Article Synopsis
- The study assessed the implementation of medical practices for adult patients with food allergies (FA) in Japan, focusing on a survey conducted at allergy specialist training facilities.
- About 33% of surveyed facilities treated patients with FA, with a notable focus on pediatric departments, where most adult cases derived from childhood-onset allergies.
- The study concluded that the current medical support for adult patients is lacking, emphasizing the need for better transitional care and more oral food challenges (OFC) to improve outcomes.
Background: The clinical importance of sensitization to 6 (Ara h 6) in Japanese children remains unelucidated. We aimed to quantitatively evaluate the clinical importance of sensitization to Ara h 6 in managing peanut allergy in Japanese children.
Methods: We retrospectively analyzed the data of children with or without symptoms induced by an oral food challenge or home dosing of up to 3 g of peanuts.
AAAAI-EAACI PRACTALL: Standardizing oral food challenges-2024 Update.
Pediatr Allergy Immunol
November 2024
This common statement of the American Academy of Allergy, Asthma and Immunology (AAAAI) and The European Academy of Allergy and Clinical Immunology (EAACI) provides an update of the 2012 published guidelines on food challenges. The guidelines equally address food challenges in the research and the clinical settings. They first address the diagnostic tests which can guide the decision to conduct a challenge.
View Article and Find Full Text PDFArticle Synopsis
- Infants under 1 year with food allergies typically need to avoid certain foods, but low-dose oral food challenges (LD-OFCs) may help safely introduce small amounts.
- A study analyzed LD-OFCs for infants allergic to hen's egg, cow's milk, or wheat, noting mostly mild skin reactions and no severe incidents like anaphylaxis.
- The findings suggest that infants can safely consume small doses of allergenic foods, indicating that complete elimination isn't always necessary when reintroducing these foods.
Article Synopsis
- The study investigates the effectiveness of recombinant Gad c 1 (rGad c 1) in diagnosing allergies to cod and horse mackerel, considering its potential as a major allergen marker for fish allergy in children.
- In this retrospective study involving 45 children with possible cod allergies and 38 with horse mackerel allergies, researchers analyzed both cod-specific and rGad c 1-specific immunoglobulin levels through oral food challenges (OFCs).
- Findings reveal that while rGad c 1 is a more reliable marker for diagnosing cod allergy compared to regular cod-specific antibodies, it is less effective for diagnosing horse mackerel allergy, indicating that further research is needed to fully understand rGad c
The global increase in dementia cases highlights the urgent need for effective treatment and care strategies. The aim of this study was to evaluate the effects of group reminiscence therapy on cognitive function, subjective well-being, and behavioral and psychological symptoms of dementia (BPSD) in older adults with moderate to severe dementia. A pre-post comparative design was used, with 49 participants receiving eight group reminiscence therapy sessions over 4 weeks.
View Article and Find Full Text PDFArticle Synopsis
- Food allergies are a growing global issue affecting quality of life and requiring strict avoidance and emergency medications for management.
- Recent clinical trials on food allergen immunotherapy have shown promise in desensitizing patients and increasing their reaction thresholds, leading to the FDA's approval of peanut oral immunotherapy.
- Japan is leading in OIT research with over 100 facilities, offering a different approach to dietary guidance compared to Europe and the US, highlighting the need for safer and more effective treatment options.
Article Synopsis
- A study was conducted to evaluate the effectiveness and safety of house dust mite sublingual immunotherapy (SLIT) in preschoolers aged 1-4 years with perennial allergic rhinitis (AR).
- After 12 months of SLIT treatment, there was a significant reduction in AR symptoms in the SLIT group compared to the control group, with mild adverse reactions reported.
- The SLIT group also showed improved immunological responses, with levels of specific antibodies increasing compared to the control group, indicating potential long-term benefits.
Article Synopsis
- Meropenem is crucial for treating severe infections and drug-resistant bacteria, but its shortage raises concerns about reliance on less effective alternatives.
- During the shortage, a study assessed the impact of post-prescription monitoring and feedback on antibiotic use and patient mortality at a hospital in Japan.
- Despite an increase in the use of alternative antibiotics, overall mortality rates remained stable, indicating that appropriate antimicrobial stewardship can mitigate negative outcomes during drug shortages.
Fenugreek allergy caused by cross-reactivity with peanut: An analysis.
J Allergy Clin Immunol Glob
August 2024
Fenugreek is often hidden in processed foods, where it is included in the generic term on food labels. Cross-reactivity of peanut and fenugreek should be considered in the management of peanut allergy.
View Article and Find Full Text PDFObjective: No questionnaire aimed at evaluating the quality of life (QOL) of children with food allergies has been developed in Japan. Therefore, this study was aimed at developing a Japanese version of a QOL questionnaire for children with food allergies to be responded to by their parents.
Methods: A 59-question primary questionnaire was developed for parents of children aged 0 to 15 years who had food allergies.
Background: Few studies have assessed the nature of accidental allergic reactions (AAR). We assessed the prevalence and risk factors for AAR in Japanese children.
Methods: This study included children with immediate-type hen's egg (HE), cow's milk (CM), wheat, or peanut allergy who developed allergic reactions within at least 2 years and were followed up regularly at a single national allergy center in Japan.
This study examines the impact of reminiscence therapy on cognitive and emotional well-being in institutionalized older patients with dementia. Conducted at the Long-Term Care Health Facility for the Elderly, the research involved 34 participants who underwent therapy sessions that included personalized discussions of past experiences. Using physiological markers such as electroencephalography alpha and beta waves, along with psychological measures such as the Hasegawa Dementia Scale-Revised, the study aimed to quantify the effects of the therapy.
View Article and Find Full Text PDFGastrointestinal stromal tumors surrounding the esophagogastric junction are often challenging to resect, with no consensus regarding the optimal surgical technique. Here in, we present a case of concurrent gastric cancer in the antrum and gastrointestinal stromal tumors adjacent to the esophagogastric junction. The patient underwent simultaneous distal gastrectomy and local resection assisted by a surgical robot, avoiding the need for total gastrectomy.
View Article and Find Full Text PDFPurpose Of Review: Food allergy is a growing health problem that affects both patients and society in multiple ways. Despite the emergence of novel diagnostic tools, such as component-resolved diagnostics (CRD) and basophil activation tests (BAT), oral food challenge (OFC) still plays an indispensable role in the management of food allergies. This review aimed to highlight the indications and safety concerns of conducting an OFC and to provide insights into post-OFC management based on recent findings.
View Article and Find Full Text PDFObjective: Quality of life (QOL) questionnaires for parents of children with food allergies have been developed in the United States and Europe. However, no original Japanese QOL questionnaire has been developed till date. We aimed to develop an original questionnaire to evaluate the QOL in parents of children with food allergies in Japan.
View Article and Find Full Text PDFBackground: Allergic reactions to milk appear sooner than those to hen's eggs, irrespective of the total dose of the oral food challenges (OFCs) and type of matrices. The reported median times for the first symptom occurrence are 20-30 min with milk and 50-60 min with eggs. However, allergic reactions due to wheat have not yet been fully investigated.
View Article and Find Full Text PDFBackground: Various bacterial species form a microbiome in the skin. In the past, dead Staphylococcus aureus derived from atopic dermatitis (AD) are taken up by keratinocytes; however, whether live S. aureus can be taken up by keratinocytes is unknown.
View Article and Find Full Text PDFBackground: Low-dose oral food challenge (LD-OFC) is an approach to avoid complete elimination in high-risk patients with wheat allergy (WA). We examined the 3-year prognosis after LD-OFC among patients who passed and failed LD-OFC.
Methods: Children with immediate-type WA aged ≤6 years with a history of reaction to ≤390 mg of wheat protein underwent their first LD-OFC with 52 mg (baseline LD-OFC).