Constraint on boric acid resistance and tolerance evolvability in .

Boric acid is a broad-spectrum antimicrobial used to treat vulvovaginal candidiasis when patients relapse on the primary azole drug fluconazole. is the most common cause of vulvovaginal candidiasis, colloquially referred to as a "vaginal yeast infection". Little is known about the propensity of to develop BA resistance or tolerance (the ability of a subpopulation to grow slowly in high levels of drug).