Investigation Of Chromium-Cobalt Coated Scaffolds On Cell Cultures In Vitro.

Introduction: The use of diverse materials for medical purposes is continuously expanding. The modification of materials which are routinely applied in medical practice as well as the development and introduction of new materials require studies on their biological activity. The first steps in this process are the preliminary short-term screening tests for cytotoxicity and biocompatibility performed on cell cultures.

Glioblastoma multiforme classified as mesenchymal subtype.

Introduction: Recently, researchers have been considering as adverse prognostic factors in primary glioblastomas not only clinical indicators but also various cellular, genetic and immunological markers. The aim of the present article was to report a case of primary glioblastoma multiforme with poor survival in a patient after surgical intervention, and to determine the unfavorable prognostic markers.

Case Report: We present a 71-year-old man with histologically verified glioblastoma multiforme and a postoperative survival of 48 days.

Psychological stress--cellular and molecular mechanisms.

Pathophysiological regulation of the stress response involves a number of complex interactions at the organismal, cellular and molecular levels. A salient feature of the stress response is the activation of the hypothalamic-pituitary-adrenal axis. Molecular studies of this phenomenon have found a number of genes which are differentially expressed in stressed individuals and control subjects.