Prevention of deep vein thrombosis in patients with aneurysmal subarachnoid hemorrhage: a best practice implementation project.

Introduction: Deep vein thrombosis (DVT) is a common complication observed in aneurysmal subarachnoid hemorrhage (aSAH) patients, which significantly increases the survival risks and reduces the patient's quality of life. However, preventive clinical measures for DVT have not been standardized; therefore, the scientific basis and effectiveness of these measures require further validation.

Objective: This study aims to employ evidence-based practices to effectively prevent the occurrence of DVT in aSAH patients.

Professional Commitment of 8-Year Medical Doctoral Degree Program Students in China: The Mediating Role of Self-Efficacy, Learning Engagement, and Academic Performance.

Background: Studying the professional commitment of a student in an 8-year medical training program of China, especially its association with academic performance, can enhance the understanding of professional loyalty in future doctors. This study aimed to investigate the self-efficacy, academic performance, professional commitment, and learning engagement of 8-year program medical students, and explore the mediating roles of professional commitment and learning engagement on the associations between self-efficacy and academic performance.

Methods: We conducted a cross-sectional study in a Chinese medical university and collected the General Self-Efficacy Scale, Professional Commitment of Undergraduates Scales, and the Utrecht Work Engagement Scale-Student from self-reported students.

Helicobacter pylori induce circ_0046854 to regulate microRNA-511-3p/CSF1 axis and enhance the resistance of gastric cancer to cisplatin.

Helicobacter pylori (HP) is considered a major risk factor for gastric cancer (GC) and during this process, cytotoxin‑associated gene A (CagA) plays in essence. The study mainly focused on the molecular mechanism of circular RNA 0046854 (circ_0046854) in HP-induced GC. Clinically, 56 cases of GC and normal tissues were collected, and the GC tissues were divided into HP-negative GC tissues (HP) and 33 HP-positive GC tissues (HP).

In situ remediation of mercury-contaminated groundwater through an in situ created reactive zone enabled by carboxymethyl cellulose stabilized FeS nanoparticles.

Faced with worldwide mercury (Hg) contamination in groundwater, efficient in situ remediation technologies are urgently needed. Carboxymethyl cellulose (CMC) stabilized iron sulfide (CMC-FeS) nanoparticles have been found effective for immobilizing mercury in water and soil. Yet, the potential use of the nanoparticles for creating an in situ reactive zone (ISRZ) in porous geo-media has not been explored.

Fast and efficient remediation of antimony-contaminated surface water and field soil using alumina supported Fe-Mn binary oxide.

Antimony (Sb) pollution in surface water and soil has earned extensive attention. Our previous study synthesized a new class of alumina supported Fe-Mn binary oxide (Fe-Mn@AlO) and found that MnO in the composite oxidized Sb(III) to Sb(V) and FeOOH and AlO played an indispensable role in adsorption of Sb(III) and Sb(V). This study further explored the removal of Sb in surface water and in situ sequestration of Sb in Sb-contaminated field soil via Fe-Mn@AlO.

Construction of a coagulation prediction model of the extracorporeal circulation circuit during hemodialysis with regional citrate anticoagulant (RCA).

Objective: To construct a prediction model of coagulation in the extracorporeal circulation circuit during hemodialysis with regional citrate anticoagulant(RCA) conditions.

Methods: This was a single-center, retrospective study. The clinical data of patients who received hemodialysis with RCA from February 2021 to March 2022 were collected.

Green remediation of mercury-contaminated soil using iron sulfide nanoparticles: Immobilization performance and mechanisms, effects on soil properties, and life cycle assessment.

Mercury (Hg) pollution in soil has grown into a severe environmental issue. Effective in situ immobilization techniques are crucially demanded. In this study, we explored the application of carboxymethyl cellulose stabilized iron sulfide nanoparticles (CMC-FeS) for in situ immobilization of Hg in soil.

Nanoporous Carbon Materials Derived from Zanthoxylum Bungeanum Peel and Seed for Electrochemical Supercapacitors.

In order to prepare biomass-derived carbon materials with high specific capacitance at a low activation temperature (≤700 °C), nanoporous carbon materials were prepared from zanthoxylum bungeanum peels and seeds via the pyrolysis and KOH-activation processes. The results show that the optimal activation temperatures are 700 °C and 600 °C for peels and seeds. Benefiting from the hierarchical pore structure (micropores, mesopores, and macropores), the abundant heteroatoms (N, S, and O) containing functional groups, and plentiful electrochemical active sites, the PAC-700 and SAC-600 derive the large capacities of ~211.

Deep learning-assisted detection and segmentation of intracranial hemorrhage in noncontrast computed tomography scans of acute stroke patients: a systematic review and meta-analysis.

Background: Deep learning (DL)-assisted detection and segmentation of intracranial hemorrhage stroke in noncontrast computed tomography (NCCT) scans are well-established, but evidence on this topic is lacking.

Materials And Methods: PubMed and Embase databases were searched from their inception to November 2023 to identify related studies. The primary outcomes included sensitivity, specificity, and the Dice Similarity Coefficient (DSC); while the secondary outcomes were positive predictive value (PPV), negative predictive value (NPV), precision, area under the receiver operating characteristic curve (AUROC), processing time, and volume of bleeding.

Exploring clinical evaluation indicators for predicting coagulation in the extracorporeal circulation circuit in hemodialysis patients receiving individualized regional citrate anticoagulation-A single-center, retrospective clinical study.

Background: Citrate anticoagulation is an important anticoagulation method in hemodialysis (HD) but cannot completely prevent the occurrence of coagulation in the extracorporeal circulation (ECC) circuit, and the clinical coagulation status can significantly affect the effect of citrate anticoagulation. In this study, the relationships between clinical coagulation status indicators and coagulation in the ECC circuit in HD patients receiving individualized citrate anticoagulant were studied to explore indicators that may predict coagulation in the ECC circuit.

Methods: This study was a single-center, retrospective clinical study, and clinical data and laboratory tests related to the coagulation status of HD patients receiving individualized regional citrate anticoagulation (RCA) were collected.

Treatment of atrazine-containing wastewater by algae-bacteria consortia: Signal transmission and metabolic mechanism.

Atrazine is a toxic endocrine disruptor. Biological treatment methods are considered to be effective. In the present study, a modified version of the algae-bacteria consortia (ABC) was established and a control was simultaneously set up to investigate the synergistic relationship between bacteria and algae and the mechanism by which atrazine is metabolized by those microorganisms.

An individualized regional citrate anticoagulation protocol for hemodialysis: a real-world retrospective study.

Objective: To evaluate the safety and effectiveness of an individualized regional citrate anticoagulation (RCA) protocol for hemodialysis.

Methods: In this single-center, retrospective study, blood coagulation in the extracorporeal circulation, adverse reactions, in vivo ionized calcium (iCa) concentrations, and the infusion dose of citrate during RCA in hemodialysis were observed in 98 patients from February 2021 to March 2022.

Results: A total of 98 patients underwent RCA during hemodialysis 362 times, and blood coagulation occurred in the extracorporeal circulation 29 times.

Non-anticoagulant factors affecting coagulation in the extracorporeal circulation circuit and the development of an individualized regional citrate anticoagulation protocol for hemodialysis: A real-world retrospective study.

Objective: To investigate non-anticoagulant factors that affect blood coagulation in the extracorporeal circulation (ECC) circuit of regional citrate anticoagulation (RCA) protocol for hemodialysis (HD).

Method: The clinical characteristics of patients undergoing an individualized RCA protocol for HD between February 2021 and March 2022 were collected; Coagulation scores, pressures in various parts of the ECC circuit, the incidence of coagulation, and citrate concentrations in the ECC circuit during treatment were determined, and non-anticoagulant factors affecting coagulation in the ECC circuit were analyzed.

Result: The lowest clotting rate was 2.

Flow Cytometry with Anti-Diffraction Light Sheet (ADLS) by Spatial Light Modulation.

Flow cytometry is a widespread and powerful technique whose resolution is determined by its capacity to accurately distinguish fluorescently positive populations from negative ones. However, most informative results are discarded while performing the measurements of conventional flow cytometry, e.g.

High-Durability Photothermal Slippery Surfaces for Droplet Manipulation Based on Ultraviolet Lithography.

Photothermal slippery surface has broad applications in many research fields for noncontacting, loss-free, and flexible droplet manipulation capability. In this work, with specific morphologic parameters and modified base materials doped by FeO, a high-durability photothermal slippery surface (HD-PTSS) was proposed and implemented based on ultraviolet (UV) lithography to achieve repeatability of more than 600 cycles. The instantaneous response time and transport speed of HD-PTSS were related to near-infrared ray (NIR) powers and droplet volume.

SlRBP1 promotes translational efficiency via SleIF4A2 to maintain chloroplast function in tomato.

Many glycine-rich RNA-binding proteins (GR-RBPs) have critical functions in RNA processing and metabolism. Here, we describe a role for the tomato (Solanum lycopersicum) GR-RBP SlRBP1 in regulating mRNA translation. We found that SlRBP1 knockdown mutants (slrbp1) displayed reduced accumulation of total chlorophyll and impaired chloroplast ultrastructure.

Aggregation of carboxyl-modified polystyrene nanoplastics in water with aluminum chloride: Structural characterization and theoretical calculation.

Nanoplastics (NPs) pollution of aquatic systems is becoming an emerging environmental issue due to their stable structure, high mobility, and easy interactions with ambient contaminants. Effective removal technologies are urgently needed to mitigate their toxic effects. In this study, we systematically investigated the removal effectiveness and mechanisms of a commonly detected nanoplastics, carboxyl-modified polystyrene (PS-COOH) via coagulation and sedimentation processes using aluminum chloride (AlCl) as a coagulant.

Field demonstration of on-site immobilization of arsenic and lead in soil using a ternary amending agent.

Soil contamination by heavy metals and metalloids has been a major environmental challenge. While various remediation technologies have been reported, field data on the remediation effectiveness have been limited. We tested a new remediation technology for on-site immobilization of As(III) and Pb(II) in a contaminated soil at an abandoned chemical plant site.

Development of Acute Myocardial Infarction Mortality and Readmission Models for Public Reporting on Hospital Performance in Canada.

Background: Given changes in the care and outcomes of acute myocardial infarction (AMI) patients over the past several decades, we sought to develop prediction models that could be used to generate accurate risk-adjusted mortality and readmission outcomes for hospitals in current practice across Canada.

Methods: A Canadian national expert panel was convened to define appropriate AMI patients for reporting and develop prediction models. Preliminary candidate variable evaluation was conducted using Ontario patients hospitalized with a most responsible diagnosis of AMI from April 1, 2015 to March 31, 2018.

Microplastics deteriorate the removal efficiency of antibiotic resistance genes during aerobic sludge digestion.

Sludge from wastewater treatment plants (WWTPs) is considered to be reservoirs of antibiotic resistance genes (ARGs), which can be efficiently removed by sludge treatment processes, e.g., aerobic sludge digestion.

Evaluation of three common alkaline agents for immobilization of multi-metals in a field-contaminated acidic soil.

We investigated three common alkaline agents (NaOH, CaO, and Mg(OH)) for immobilization of four heavy metals (Pb, Zn, Cu, and Cd) in a field-contaminated soil and elucidated the underpinning principles. NaOH caused the highest pH spike in the soil, while CaO and Mg(OH) served as a longer-lasting source of OH. Amending the soil with CaO or Mg(OH) at ≥0.

The influence of cooperative action intention on object affordance: evidence from the perspective-taking ability of individuals.

In complex interactive scenarios, action understanding lies at the heart of social interactions. Nevertheless, the ability to understand action intention may differ among people. The current study distinguished two groups of participants with different social intention-understanding abilities (high and low) based on a perspective-taking task to investigate the influence of social intention on object affordance under conditions of individual and cooperative action intention.

Realization of flexible and parallel laser direct writing by multifocal spot modulation.

In this investigation, we propose a strip segmentation phase (SSP) method for a spatial light modulator (SLM) to generate independent multifocal spots when the beam passes through a high numerical aperture (NA) lens. With the SSP method, multifocal spots can be generated with each spot independently, flexibly and uniformly distributed. The performance of the SSP method is first validated with numerical simulation.

Occurrence and fate of linear alkylbenzenes and their potential as environmental molecular markers in highly urbanized river systems.

Rapid industrialization, urbanization, and population growth have led to the common occurrence of black-stinking urban rivers. Assessing regional anthropogenic influences is beneficial to develop effective remediation strategies. This study comprehensively investigated the occurrence and fate of linear alkylbenzenes (LABs) as molecular markers of anthropogenic influences in three media (filtered water, suspended particulate matter (SPM), and sediment) in a highly urbanized river (Baihaimian River) in Guangzhou, South China.