Front Endocrinol (Lausanne)
January 2025
Sertoli cells (SCs), as the somatic cells in the testis of male mammals, play a crucial role in the close association with germ cells. The blood-testicular barrier (BTB), established by their tight junctions, provides immune protection to germ cells, leading to their characterization as "sentinel" cells. Moreover, the physiological process of testicular development and spermatogenesis in male animals is intricately tied to the secretory activities of SCs.
View Article and Find Full Text PDFCancer continues to be a leading cause of death worldwide, highlighting the urgent need for the development of new therapeutic strategies. Chrysophanol, a naturally occurring anthraquinone compound, has demonstrated significant potential in cancer treatment due to its diverse biological activities. This review delves into the mechanisms through which chrysophanol exerts its anti-cancer effects, including the induction of cell cycle arrest, promotion of apoptosis, regulation of autophagy, and initiation of necrosis across various cancer cell lines.
View Article and Find Full Text PDFBackground: Pneumococcus is a common cause of pneumonia, meningitis, and other serious infections in children. The previous study has proved that the 13-valent pneumococcal conjugate vaccine (PCV13) has sufficient immunogenicity in children. The data on long-term persistence of immunity will help the follow-up development work of pneumococcal vaccines.
View Article and Find Full Text PDFFixed Drug Eruptions (FDE) represent a distinctive type of adverse drug reaction, typically characterized by recurring, sharply demarcated skin lesions occurring at identical sites with each administration of the causative drug. A less frequent, albeit significant manifestation of FDE, is balanoposthitis, an inflammatory condition affecting the glans penis and prepuce. This rare case report explores the clinical presentation, diagnosis, and therapeutic management of FDE-induced balanoposthitis in a 34-year-old male patient who developed this condition following azithromycin administration to treat a pulmonary infection.
View Article and Find Full Text PDFAccurate, fast, and reliable modeling and optimization methods play a crucial role in designing light field display (LFD) system. Here, an automatic co-design method of LFD system based on simulated annealing and visual simulation is proposed. The process of LFD content acquisition and optical reconstruction are modeled and simulated, the objective function for evaluating the display effect of the LFD system is established according to the simulation results.
View Article and Find Full Text PDFThree-dimensional (3D) light field displays require samples of image data captured from a large number of regularly spaced camera images to produce a 3D image. Generally, it is inefficient to generate these images sequentially because a large number of rendering operations are repeated in different viewpoints. The current 3D image generation algorithm with traditional single viewpoint computer graphics techniques is not sufficiently well suited to the task of generating images for the light field displays.
View Article and Find Full Text PDFThe exiting simulation method is not capable of achieving three-dimensional (3D) display result of the light field display (LFD) directly, which is important for design and optimization. Here, a high-speed visual simulation method to calculate the 3D image light field distribution is presented. Based on the backward ray tracing technique (BRT), the geometric and optical models of the LFD are constructed.
View Article and Find Full Text PDFA general integral imaging generation method based on the path-traced Monte Carlo (MC) method and recurrent convolutional neural networks denoising is presented. According to the optical layer structure of the three-dimensional (3D) light field display, screen pixels are encoded to specific viewpoints, then the directional rays are cast from viewpoints to screen pixels to preform the path integral. In the process of the integral, advanced illumination is used for high-quality elemental image array (EIA) generation.
View Article and Find Full Text PDFA high-efficient computer-generated integral imaging (CGII) method is presented based on the backward ray-tracing technique. In traditional CGII methods, the total rendering time is long, because a large number of cameras are established in the virtual world. The ray origin and the ray direction for every pixel in elemental image array are calculated with the backward ray-tracing technique, and the total rendering time can be noticeably reduced.
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