Publications by authors named "YanXiang Wang"

Nitrogen-doped graphene quantum dots (N-GQDs) are widely used in biosensing, catalysis, and energy storage due to their excellent conductivity, high specific surface area, unique quantum size effects, and optical properties. In this paper, we successfully synthesized N-GQDs using a facile hydrothermal approach and investigated the effects of different hydrothermal temperatures and times on the morphology and structure of N-GQDs. The results indicated that the size of N-GQDs gradually increased and they eventually aggregated into graphene fragments with increasing temperature or reaction time.

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With the increasing demand for effective electromagnetic wave (EMW) absorbers due to the proliferation of electronic devices and 5G communication systems, traditional wave-absorbing materials can no longer meet the current requirements. Thus, this research introduces a three-dimensional (3D) composite material consisting of PMMA@Mxene@Co₃O₄ microspheres, prepared through in situ self-assembly and hydrothermal growth. The strong electrical conductivity of Mxene, combined with the magnetic loss of Co₃O₄, ensures enhanced dielectric-magnetic synergy, leading to excellent EMW absorption.

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Objective: To investigate the predictive value of intraoperative bulbocavernosus reflex (BCR) monitoring for voiding dysfunction post-operatively in patients with distal intraspinal tumors and to determine an appropriate timing for postoperative follow-up assessment.

Methods: Patients with distal intraspinal tumors who underwent surgery with BCR monitoring were collected. Patients were classified into BCR absent and present groups according to the monitoring responses at the end of surgery.

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  • 11β-hydroxylase deficiency (11β-OHD) is a genetic disorder that results from mutations in the CYP11B1 gene and is a common cause of congenital adrenal hyperplasia, affecting the hormonal balance in affected individuals.
  • The study investigated two siblings from a Chinese family with 11β-OHD, using various advanced genetic testing methods to identify the specific mutations affecting them.
  • The researchers discovered two pathogenic variants in the CYP11B1 gene, highlighting the effectiveness of using long-range PCR-based next-generation sequencing and target long-read sequencing for accurate genetic diagnosis.
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  • The study investigates the immune and metabolic profiles of Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) using single-cell RNA sequencing of blood cells from patients and healthy controls, revealing significant cellular composition changes.
  • It shows an increase in T cells but a notable decrease in other immune cells like NKs and monocytes, suggesting complex alterations in immune function among ME/CFS patients.
  • The research identifies potential biomarkers and pathways, such as ESRRA-APP-CD74, linking immune dysfunction to neurological symptoms, hinting at the disease's autoimmune and immunodeficiency aspects.
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  • This study evaluated high variability phonetic training (HVPT) for children with cochlear implants (CIs), specifically focusing on improving their ability to produce lexical tones.
  • Sixteen children underwent a five-session HVPT, while another sixteen received no training; their tone production was assessed before, immediately after, and ten weeks post-training.
  • Results showed significant improvements in Mandarin tone production among the trained group, including lasting changes in tone characteristics, highlighting the potential of HVPT in clinical practices for pediatric CI users.
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  • Pathogenic microorganisms are increasingly resistant to traditional drugs, prompting the search for alternative treatments like nano-based antibacterial agents.
  • This study synthesized biogenetic tellurium nanoparticles (Bio-TeNPs) from a widely recognized edible plant, which exhibited diameters of 20-50 nm and significant antibacterial properties against various pathogens.
  • Bio-TeNPs demonstrated effective biofilm inhibition rates and a remarkable 100% clearance rate against specific bacteria on glass surfaces, highlighting their potential as a new strategy in fighting bacterial infections.
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  • Reduced graphene oxide (RGO) is a promising electrode material for electrochemical energy storage, but issues like aggregation and limited active sites hinder its performance.
  • A new solvothermal method enhances RGO by adding functional groups, reducing aggregation, and incorporating nitrogen, resulting in a high-performing electrode (RGO-N(DMF)) with improved conductivity and activity.
  • The RGO-N(DMF) electrode exhibits excellent specific capacity and rate performance, and maintains flexibility and performance after extensive bending, making it a strong candidate for practical applications in flexible energy storage devices like zinc-ion hybrid supercapacitors.
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Morphological engineering is crucial for conceiving high-efficiency electromagnetic wave (EMW) absorption materials. However, for carbon fiber-based composites, the management of micromorphology is significantly astricted by complex fabrication. It remains highly challenging to clarify the micromorphological influences on the EMW loss mechanism of carbon fiber-based absorption materials.

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The present study provides a facile one-pot pyrolysis strategy to prepare serial nitrogen-doped (N-doped) metal/carbon composites derived from six types of metal ethylenediaminetetraacetic acid (EDTA-M, M = Co, Cu, Mn, Fe, Mg, and Ca). N-doped Co/C composite integrated carbonaceous with magnetic components to attain dielectric-magnetic double loss mechanisms. The minimum reflection loss and effective absorption bandwidth reached -57.

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  • Helicobacter pylori is a major carcinogenic pathogen linked to stomach cancer, known for its high prevalence and resistance, making treatment challenging.
  • Researchers used a graph neural network model to identify a promising new compound, a berberine derivative named 8, which effectively inhibits both drug-susceptible and resistant H. pylori strains.
  • The compound 8 shows strong gastric retention and performs comparably to standard triple therapies without affecting intestinal bacteria, positioning it as a potential novel treatment for resistant H. pylori infections.
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A photorechargeable supercapacitor was constructed using vanadium pentoxide (VO), reduced graphene oxide hydrogel (rGH), and zinc trifluoromethanesulfonate (Zn(CFSO)) as the photoanode, cathode, and electrolyte, respectively. The phase composition, microstructure, chemical structure, light absorption, and specific surface area of the synthesized products and the electrochemical performance of the rGH/VO supercapacitor were investigated using X-ray diffraction (XRD), scanning electron microscopy (SEM), Fourier-transform infrared spectroscopy (FT-IR), Raman spectroscopy, UV-Vis spectroscopy, the Brunauer-Emmett-Teller (BET) method, and an electrochemical workstation, respectively. The results show that the device has a specific capacity of 164 F g at 0.

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Bombyx mori L. (Lepidoptera: Bombycidae) nucleopolyhedrovirus (BmNPV) is a serious pathogen causing huge economic losses to sericulture. There is growing evidence that the gut microbiota of silkworms plays a critical role in shaping host responses and interactions with viral infection.

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Based on MnO/carbon cloth (CC) composite materials, an Ag-doped MnO nanowire, self-assembled, urchin-like structure was synthesized in situ on the surface of CC using a simple method, and a novel and efficient flexible electrode material for supercapacitors was developed. The morphology, structure, elemental distribution, and pore distribution of the material were analyzed using SEM, TEM, XRD, XPS, and BET. The electrochemical performance was tested using cyclic voltammetry (CV) and galvanostatic charge/discharge (GCD).

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Background: The emergence and spread of vancomycin-resistant enterococci (VRE) have posed a significant challenge to clinical treatment, underscoring the need to develop novel strategies. As therapeutic options for VRE are limited, discovering vancomycin enhancer is a feasible way of combating VRE. Gambogic acid (GA) is a natural product derived from the resin of Garcinia hanburyi Hook.

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Supercapacitors (SCs) are a novel type of energy storage device that exhibit features such as a short charging time, a long service life, excellent temperature characteristics, energy saving, and environmental protection. The capacitance of SCs depends on the electrode materials. Currently, carbon-based materials, transition metal oxides/hydroxides, and conductive polymers are widely used as electrode materials.

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Nanofiltration (NF) will play a crucial role in salt fractionation and recovery, but the complicated and severe mixed scaling is not yet fully understood. In this work, the mixed scaling patterns and mechanisms of high-pressure NF in zero-liquid discharge (ZLD) scenarios were investigated by disclosing the role of key foulants. The bulk crystallization of CaSO and Mg-Si complexes and the resultant pore blocking and cake formation under high pressure were the main scaling mechanisms in hypersaline desalination.

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The COVID-19 pandemic highlights the urgent need to develop effective small-molecule antivirals. Thirty-three novel biaryl amide derivatives were synthesized and evaluated for anti-coronaviral activity. Some significant SARs were uncovered and the intensive structure modifications led to the most active compounds 8b and 8h.

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Silk nanofibers (SNF) have great applications in high-performance functional nanocomposites due to their excellent mechanical properties, biocompatibility, and degradability. However, the preparation of SNF by traditional methods often requires the use of some environmentally harmful or toxic reagents, limiting its application in green chemistry. In this paper, we successfully prepared SNF using natural silk as raw material and solvent stripping technology by adjusting the solvent concentration and solution ratio (the diameter of about 120 nm).

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  • Hand, foot, and mouth disease (HFMD) caused by enterovirus A71 (EV-A71) currently has no specific treatments, but Pien Tze Huang (PZH) shows promise in inhibiting the virus's replication.
  • Research indicates that PZH significantly reduces viral protein expression and viral loads in cells and protects mice from EV-A71 infection, outpacing the effects of the common antiviral drug Ribavirin.
  • A study of the underlying mechanisms suggests PZH may work by suppressing certain cellular pathways (PI3K/AKT/mTOR and NF-κB), indicating its potential as a therapeutic option for managing EV-A71 infections.
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Apple stem pitting virus is a species in the genus Foveavirus in the family Betaflexiviridae. Apple stem pitting virus (ASPV) commonly infects apple and pear plants grown worldwide. In this study, by integrating bimolecular fluorescence complementation, split-ubiquitin-based membrane yeast two-hybrid, and Agrobacterium-mediated expression assays, the interaction relationships and the subcellular locations of ASPV proteins TGBp1-3 and CP in Nicotiana benthamiana leaf cells were determined.

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Perovskite solar cells (PSCs) were first proposed in 2009. They have the advantages of low cost, a simple manufacturing process and excellent photoelectric performance. PSC electrodes are mainly made from precious metals such as gold and silver.

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Pseudomonas aeruginosa is one of the multipledrug-resistant (MDR) Gram-negative pathogens with few drugs available for treatment. Antibiotic adjuvant approach provides an alternative and complementary strategy. In this study, the stereo-structure-activity relationship of monobactams against MDR Gram-negative organisms was extended.

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Despite observed ethnic differences in eating patterns and obesity, evidence in China is limited. This study examined ethnic differences in eating patterns and their associations with weight outcomes among multi-ethnic adults in West China. A cross-sectional survey collected self-reported data on demographics, eating behaviours, weight and height in 2021.

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