Publications by authors named "YanRong Yin"
Article Synopsis
- This study examined the link between PM 2.5 air pollution and blood pressure (BP) among 36,792 adults in southeast China, focusing on specific chemical components of PM 2.5.
- Quantile regression models showed that as levels of PM 2.5 and its chemicals (like ammonium and black carbon) increased, both systolic and diastolic blood pressure rose, especially in individuals with initially high BP.
- The findings indicate that long-term exposure to PM 2.5, particularly ammonium and black carbon, significantly raises BP risk, with stronger effects observed in high BP quantiles.
Introduction: Accurately filling out death certificates is essential for death surveillance. However, manually determining the underlying cause of death is often imprecise. In this study, we investigate the Wide and Deep framework as a method to improve the accuracy and reliability of inferring the underlying cause of death.
View Article and Find Full Text PDFBackground: Greenness exposure is beneficial to human health, but its potential mechanisms through which the risk for metabolic syndrome (MetS) could be reduced have been poorly studied. We aimed to estimate the greenness-MetS association in southeast China and investigate the independent and joint mediation effects of physical activity (PA), body mass index (BMI), and air pollutants on the association.
Methods: A cross-sectional study was conducted among the 38,288 adults based on the Fujian Behavior and Disease Surveillance (FBDS), established in 2018.
Aims: Greenness offers health benefits to prevent diabetes in urban areas. However, urban-rural disparities in this association have not been explored, with the underlying pathways understudied as well. We aimed to investigate and compare the associations and potential pathways between residential greenness and the risks for diabetes and prediabetes in urban and rural areas.
View Article and Find Full Text PDFBackground: Evidence on associations of residential greenness with dyslipidemia is limited, particularly regarding dose-response relations and mediation.
Objectives: To investigate associations between greenness and dyslipidemia, non-linear dose-response relationships and mediators.
Methods: This cross-sectional study draws on the 2018 Fujian Behavior and Disease Surveillance (FBDS) cohort that used multi-stage stratified random sampling from the general population of Fujian Province, China.
Article Synopsis
- COPD is a significant public health issue in southeast China, with a prevalence of 11.6% among adults aged 40 and older, determined through a study of 5,486 participants between 2019-2020.
- Key risk factors identified include being male, over 70 years of age, having a low BMI, parental history of respiratory diseases, and smoking (current or former).
- The study emphasizes the need for the Chinese government to take urgent action to mitigate these risk factors and improve disease control and prevention strategies.
Osteoporosis is a reduction in skeletal mass due to the decrease of osteogenic ability and the activation of the osteoclastic function. Inhibiting bone resorption and accelerating the new bone formation is a promising strategy to repair the bone defect of osteoporosis. In this study, we first systematically investigated the roles of Chinese medicine Asperosaponin VI (ASP VI) on osteogenic mineralization of BMSCs and osteoclastogenesis of BMMs, and then explored the synergistic effect of ASP VI and BS (BMP-2 immobilized in 2-N, 6-O-sulfated chitosan) on bone formation.
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- A novel biodegradable elastomeric poly(citric acid-1,8-octanediol-1,4-bis(2-hydroxyethyl)piperazine (BHEp)) was created to neutralize acidity in bone defects, aiding cell growth and bone repair.
- The incorporation of the alkaline fragment BHEp into 3D-printed POPC/β-TCP scaffolds improves biocompatibility, cell adhesion, and proliferation of mesenchymal stem cells while reducing inflammation.
- The study demonstrates that these scaffolds promote bone regeneration in a rat femoral defect model, presenting a potential strategy for developing biodegradable materials that mitigate acidic degradation.
Background There are limited data about cardiac resynchronization therapy (CRT) in adult congenital heart disease. We aimed to assess early and late outcomes of CRT among patients with adult congenital heart disease. Methods and Results We retrospectively studied 54 patients with adult congenital heart disease (median age, 46 years; range, 18-73 years; 74% men) who received CRT implantation (biventricular paced >90%) between 2004 and 2017.
View Article and Find Full Text PDFThe fibrotic response of vascular smooth muscle cells (VSMCs) takes responsibilities in atherosclerosis. Advanced glycation end products (AGEs) induce and promote the fibrotic responses of VSMCs. Matrine shows potent anti-fibrotic and cardio-protective effects.
View Article and Find Full Text PDFAims: QT interval prolongation is common in patients with stroke and increases the risk of malignant arrhythmia and sudden death. Our aim was to analyze differences in the QT interval and electrocardiogram abnormalities between acute ischemic stroke patients and controls.
Methods: We retrospectively collected data from 273 patients with acute ischemic stroke from the neurological intensive care unit and 495 controls from other departments.
Context: Allicin is a potential antiarrhythmic agent. The antiarrhythmic properties of allicin rely on its blockade of various cardiac ion channels. The l-type calcium (Cav1.
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- Metabolic syndrome (MetS) is linked to nephropathy, with adipocytokines from perirenal adipose tissue (PRAT) playing a role in its development.
- Research focused on how leptin from PRAT worsens nephropathy and whether the drug telmisartan can help protect kidney function by reducing leptin levels in a rat model of MetS.
- Long-term treatment with telmisartan improved metabolic health, renal function, and PRAT health, indicating its potential as a therapeutic option for MetS-related kidney issues.