[Serum levels of macrophage colony stimulating factor in the patients with Alzheimer's disease].

Objective: To investigate the availability of serum level of macrophage clony stimulating factor (M-CSF) as a marker for early diagnosis of Alzheimer's disease (AD).

Methods: The serum levels of M-CSF in 70 patients with AD, 52 healthy controls, 22 patients with VAD (vascular dementia) were measured and the serum levels of IL-1 beta, IL-6, TNF-alpha in 32 patients with AD and 20 controls were measured as well.

Results: Serum levels of M-CSF were significantly elevated in patients with AD when compared with healthy controls (P < 0.