Anti-inflammatory effects of Tao Hong Si Wu Tang in mice with lung cancer and chronic obstructive pulmonary disease.

Background: Lung cancer (LC) combined with chronic obstructive pulmonary disease (COPD) is a common combination of comorbidities. Anti-inflammation and modulation of oxidative/antioxidative imbalance may prevent COPD-induced LC, and are also crucial to the treatment of LC combined with COPD. Modern studies have shown that Tao Hong Si Wu Tang (THSW) has vasodilatory, anti-inflammatory, anti-fatigue, anti-shock, immunoregulatory, lipid-reducing, micronutrient-supplementing, and anti-allergy effects.

Case-controlled study of tuberculosis in in-vitro fertilisation-embryo transfer and natural pregnancy.

Objective: To improve the understanding of the clinical features and imaging characteristics of pregnant women with and without in-vitro fertilisation-embryo transfer combined with pulmonary tuberculosis (TB).

Methods: A retrospective analysis was conducted involving 50 patients with pregnancy who had pulmonary TB and were admitted to the Third People's Hospital of Kunming (China) between 1 January 2017 and 31 December 2021. These patients were divided into an in-vitro fertilisation and embryo transfer (IVF-ET) conception group and a natural conception group according to the conception method.

Characterization of the Complete Chloroplast Genome of D.Don 1825 (Ericaceae).

D.Don 1825 (Ericaceae) is a traditional Chinese medicinal plant used to treat rheumatoid arthritis. The complete chloroplast genome of .

[PM Source Apportionment Based on a Variety of New Receptor Models].

In order to understand the applicability of various new receptor models, four receptor models, including the positive matrix factorization/multilinear engine 2-species ratio (PMF/ME2-SR), partial target transformation-positive matrix factorization (PTT-PMF), positive matrix factorization (PMF), and chemical mass balance (CMB), were used to analyze and verify the atmospheric fine particulate matter (PM) data of a typical city in northern China. It was found that coal combustion (25%-26%), dust (19%-21%), secondary nitrate (17%-19%), secondary sulfate (16%), vehicle emissions (13%-15%), biomass burning (4%-7%), and steel (1%-2%) had a contribution to PM. By comparing the source profiles and source contributions obtained by different models and calculating the coefficient of differences (CD) and average absolute error (AAE) of each source, we found that although the source apportionment results of the four models were in good agreement (the average CD value was between 0.

Characterization of the complete plastid genome of (Ericaceae).

is an evergreen shrub in the family Ericaceae. It is used as a source of the Chinese traditional medicine, Tougucao, with distribution of the junction of eastern Himalaya and Hengduan Mountain. The chloroplast genome of is 175,649 bp in length with 135 genes, including eight rRNA genes, 39 tRNA genes, and 85 protein-coding genes.

The complete chloroplast genome of Wall. (Ericaceae) from Yunnan, China, an aromatic medicinal plant in the wintergreens.

Gaultheria fragrantissima (Ericaceae) is an aromatic medicinal plant with high concentrations of the secondarymetabolite methyl salicylate (oil of wintergreen). In this study, the complete chloroplast genomeof G. fragrantissima was sequenced.

[Modeling Studies of Source Contributions to PM in Chengdu, China].

This study establishes eight emission scenarios in the air pollutant emissions inventory of Chengdu City, China. We use the Weather Research and Forecasting and Community Multiscale Air Quality (WRF-CMAQ) models and a "zero-out" approach to investigate contributions of air pollution transport and sources to aerosol fine particulate matter (PM) pollution in Chengdu City during January, April, July, and October 2015. The results showed that PM pollution in Chengdu City was serious during these months and reached >130 μg·m in January.

[Treatment of Mild-to-moderate Bronchial Asthma (Heat Wheezing Syndrome) Patients at Acute Onset with Western Medicine Combined Danlong Oral Liquid: a Multi-center, Randomized Double- blinded, Positive-controlled Clinical Trial].

Objective: To observe the efficacy and safety of Danlong Oral Liquid (DOL) combined Western medicine (WM) in treating mild-to-moderate bronchial asthma patients (heat wheezing syndrome) at acute onset.

Methods: Totally 480 mild-to-moderate bronchial asthma patients (heat wheezing syndrome) at acute onset were randomly assigned to two groups in the ratio 3:1, the treatment group (360 cases) and the control group (120 cases). All patients received basic WM treatment.

[The combined effects of beta-sheet breaker and hUCMSC on APP transgenic mice].

Objective: To study the effect of combining the injection of beta-sheet breaker H102 with human umbilical cord mesenchymal stem cell (hUCMSC) on APP transgenic mice behavior, P-tau, apoptosis and the expression of relevant enzymes in the brain.

Methods: APP transgenic mice were randomly divided into model group, hUCMSC group, H102 group, H102 with hUCMSC group and a group of C57BL/6J mice with the same age and background was set as normal. After two weeks and four weeks, the ability of spatial reference memory was tested by Morris Water Maze.

Histological and mechanical properties of autologous living tissue biotubes.

The aim of this study was to explore and evaluate biotubes consisting of autologous tissues. The biotubes were prepared by intra-abdominally embedding silicon rods as moulds. The specimens were analyzed by mechanical tests, histological observation and superficial study.

Treatment of common cold patients with the shi-cha capsule: a multicenter, double-blind, randomized, placebo-controlled, dose-escalation trial.

This study was designed to determine the therapeutic efficacy and safety of the Shi-cha capsule, a Chinese herbal formula, in the treatment of patients with wind-cold type common cold. In our multi-center, prospective, double-blind, randomized, placebo-controlled, dose-escalation trial, patients with wind-cold type common cold received 0.6 g of Shi-cha capsule plus 0.

[Detection of isocitrate dehydrogenase 1 gene mutation in 205 AML patients and its clinical significance].

This study was purposed to detect the mutation of isocitrate dehydrogenase 1 (IDH-1) gene in patients with acute myeloid leukemia (AML) and to explore its clinical significance. The genomic DNA was extracted from mononuclear cells (MNC) of bone marrow or peripheral blood in 205 adult AML patients, the exon 4 of IDH1 gene was amplified by PCR, then the sequencing and comparison were performed. The results showed that IDH1 mutation was detected in 9 (4.

Anatomical characterization of the neuropeptide S system in the mouse brain by in situ hybridization and immunohistochemistry.

Neuropeptide S (NPS) is the endogenous ligand for GPR154, now referred to as neuropeptide S receptor (NPSR). Physiologically, NPS has been characterized as a modulator of arousal and has been shown to produce anxiolytic-like effects in rodents. Neuroanatomical analysis in the rat revealed that the NPS precursor mRNA is strongly expressed in the brainstem in only three distinct regions: the locus coeruleus area, the principal sensory trigeminal nucleus, and the lateral parabrachial nucleus.

[Influence of H102 on the expression of amyloid protein and amyloid precursor protein in the hippocampus of APP695 transgenic mice].

Objective: To observe the influence of H102 on the expression of amyloid protein and amyloid precursor protein in the hippocampus of APP695 transgenic mice.

Methods: The 9-month-old APP695 transgenic mice were randomly divided into the model group and the H102 group; C57BL/6J mice were adopted as normal control group. The H102 group were injected with H102 in a dose of 3 microl/per mouse in lateral ventricle, once a day, for ten days; while the model group and the control group were injected with saline.

Chinese herbs in treatment of influenza: a randomized, double-blind, placebo-controlled trial.

Objective: To investigate the efficacy and safety of Antiwei, a traditional Chinese prescription, in the treatment of influenza.

Methods: In a multi-center, randomized, double-blind, placebo-controlled trial, we recruited 480 adults aged 18 to 65 years within 36 h of onset of influenza-like symptoms. There were 225 patients with confirmed influenza.

[Different types of feeder cells for maintenance of human embryonic stem cells].

Objective: To compare the effects of different types of feeder cells on supporting undifferentiation and high proliferation of human embryonic stem cells (hESC).

Methods: hESC were seeded on mouse embryonic fibroblasts (MEF), human marrow stromal cells (hMSC), and human foreskin fibroblasts (hFF), respectively. Colony number, cell quantity after digestion, and survival rate were observed by alkaline phosphatase (AP) staining and Trypan blue, and the biological properties of hESC after 5 passages were observed by immunofluorescence staining.

Neuropeptide S-mediated control of fear expression and extinction: role of intercalated GABAergic neurons in the amygdala.

A deficient extinction of memory is particularly important in the regime of fear, where it limits the beneficial outcomes of treatments of anxiety disorders. Fear extinction is thought to involve inhibitory influences of the prefrontal cortex on the amygdala, although the detailed synaptic mechanisms remain unknown. Here, we report that neuropeptide S (NPS), a recently discovered transmitter of ascending brainstem neurons, evokes anxiolytic effects and facilitates extinction of conditioned fear responses when administered into the amygdala in mice.

[Expression profile of clock genes during the process of embryonic stem cells differentiation].

Objective: To analysis the expression profile of7 clock genes during mouse embryonic stem cell (mES) differentiation.

Methods: Mouse ES cells of the line 129 were cultured and induced to differentiate into neurons by 5 stages method. The expression of 7 clock genes: BMAL1, CLOCK, CRY1, CRY2, PER1, PER2, and PER3 in the five stages were determined by RT-PCR.

[Cephalometric analysis of implant anchorage-assisted retraction of anterior teeth].

Purpose: The purpose of this study is to compare the different effects of alveolar bone remolding due to retraction of anterior teeth by two types of anchorage mini-screw implant or regular maximum anchorage.

Methods: The sample comprised 26 orthodontic patients with upper dental alveolar bone protrusion and mild crowding. The treatment plan was to remove the four first bicuspids.

Distribution of neuropeptide S receptor mRNA and neurochemical characteristics of neuropeptide S-expressing neurons in the rat brain.

Neuropeptide S (NPS) and its receptor (NPSR) constitute a novel neuropeptide system that is involved in regulating arousal and anxiety. The NPS precursor mRNA is highly expressed in a previously undescribed group of neurons located between the locus coeruleus (LC) and Barrington's nucleus. We report here that the majority of NPS-expressing neurons in the LC area and the principal sensory trigeminal nucleus are glutamatergic neurons, whereas many NPS-positive neurons in the lateral parabrachial nucleus coexpress corticotropin-releasing factor (CRF).

[Continuously modeling research on the transfer and transform processes of phosphorus in Heihe River watershed].

Taking supply water source of Xi'an city as an example, by the help of Matlab software, using fill and yield model, the Inverse-Gauss flow concentration model, runoff-sediment relation model and Viney model, the transfer and transform processes of phosphorus from 1981 to 1990 were modeled continuously. Phosphorus pollution loads of Heihe River were also estimated. The result shows that the continuous modeling result accorded with the generic law of phosphorus loss.

Neuropeptide S and its receptor: a newly deorphanized G protein-coupled receptor system.

Neuropeptide S (NPS) is a recently discovered bioactive peptide that has shed new light on the neurobiology of sleep/wakefulness regulation and anxiety-like behavior. NPS can potently promote arousal and suppress all stages of sleep. This effect might be modulated by NPS receptors expressed in thalamic centers that are relays for transmitting arousing stimuli originating from the brainstem to the cortex.