Aristololactams and aporphines from the stems of Fissistigma oldhamii (Annonaceae).

Two aristololactams, aristololactam GI (1) and aristololactam GII (2), and three aporphines, fissistigamide A (3), fissistigamide B (4) and fissistigmine (5), together with nineteen known alkaloids, one flavone and one anthraquinone were isolated from the ethanol extracts of the stems of Fissistigma oldhamii (Annonaceae). Their structures were elucidated primarily by analysis of NMR, IR, UV, MS and CD data. Alkaloid 1 is a chiral aristololactam formed from a phenylpropanoid derivative attached to a 3,4-dihydroxy aristololactam scaffold.

Hypnotic effect of jujubosides from Semen Ziziphi Spinosae.

Ethnopharmacological Significance: Semen Ziziphi Spinosae, the seed of Ziziphus jujuba Mill. var. spinosa (bunge) Hu ex H.

[Studies on chemical constituents from seed of Psoralea corylifolia].

Objective: To study the chemical constituents of Psoralea corylifolia.

Method: Chromatographic methods were used to separate compounds, and spectroscopic methods were used to determine the structures.

Result: Five compounds were isolated and identified as furano (2", 3", 7, 6)-4'-hydroxyflavanone (1), psoralidin (2), genistein (3), psoralen (4), isopsoralen (5).

Spinosin, a C-glycoside flavonoid from semen Zizhiphi Spinozae, potentiated pentobarbital-induced sleep via the serotonergic system.

Semen Zizhiphi Spinozae has been used extensively for the treatment of insomnia. This study investigated the effect and possible mechanism of action of spinosin (also known as 2''-beta-o-glucopyranosyl swertisin), a major constituent of semen Zizhiphi Spinozae, on sleep in mice. The present results showed that spinosin significantly and dose-dependently augmented pentobarbital (45 mg/kg, i.

[Structure identification of jujuboside E].

Aim: To study the chemical constituents of the seeds of Ziziphus jujuba Mill var. spinosa (Bunge) Hu ex. H.

[Studies on the phenylpropanoids from Eucommia ulmoides].

Objective: To study the chemical constituents from the leaves of Eucommia ulmoides.

Method: The constituents were isolated by chromatography method and the structures were identified on the basis of spectral analysis.

Result: Six compounds, ursolic acid(1), beta-sitosterol(2), p-coumaric(3), caffeic acid ethyl ester(4), chlorogenic acid(5) and syringin(6) were obtained.